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The natural flavolignan deoxypodophyllotoxin (DPPT) inhibits tubulin polymerization and induces cell cycle arrest at G(2)/M, followed by apoptosis. Analyzing the neurogenic fate decisions mediated by D2/D3 signaling pathways may lead to new avenues to induce neural repair in the adult brain.

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The CSAR was evaluated by the RSNA response to epicardial application of capsaicin. Findings from this study provide insight into the usefulness of PSA velocity as a detection marker for aggressive prostate cancer. The relevant role of zinc in osteoporosis, its correlation with nutrient intake and the modifications of its urinary and serum levels, have been demonstrated.

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PTH concentration in the cytosolic fraction of the metastatic tumor was elevated compared to that from a control patient with no calcium metabolic disorders in vitro. Among the plants examined, Acer ginnala, Illicium religiosum and Cornus macrophylla exerted the most strong inhibitory activity on aldose reductase. Addition of EGF causes a loss of IRF3 transcriptional activity and activation of canonical signaling pathways such as ERK. We proposed a parameter estimation framework to address these issues that integrates temporal information with periodic information embedded in the measurements used to estimate these parameters.

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A linkage analysis of Co and 26 other loci indicates that Co is not closely linked to AcP1, ABO, AK1, Ch, Do, GLO, Gm, GPT, HLA, Hp, K, Lu, MN, PGM1 or Rh and does not lie between PGD and PGM1 on chromosome 1. Serial noninvasive targeted imaging of peripheral angiogenesis: validation and application of a semiautomated quantitative approach.

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The importance of travel as a risk factor for Chlamydia trachomatis infection was evaluated among a series of young people consecutively tested. Different expression patterns were observed for the two cDNAs, pSO5 being expressed earlier than pSOM in seed maturation and oil deposition.

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One monkey received identical implants of empty capsules and served as a control. Unusual posttraumatic change in the kidney under the clinical picture of a tumor Results of the survey showed that a majority of schools did not offer a course in chest physical therapy.

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Importantly, RNAi-mediated blunting of CycG2 attenuates doxorubicin-induced cell cycle checkpoint responses in multiple cell lines. Among them, 32 patients underwent synchronous hepatectomy with gastrectomy and the remaining 32 patients underwent metachronous hepatectomy.

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High risk human papillomaviruses (HPVs) known to be closely associated with cervical cancer, such as HPV16 and HPV18, have the potential to immortalize human epithelial cells in culture. Advances in electronic tracking devices and intrinsic biogeochemical markers have greatly improved our ability to track animal movements on ocean-wide scales. Chronic ethanol consumption: from neuroadaptation to neurodegeneration.

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Patient and staff perspectives on the use of a computer counseling tool for HIV and sexually transmitted infection risk reduction. The fluorescent free fatty acid indicator (ADIFAB) was used to measure the amount of FFA remaining in the aqueous phase. To clarify their disease association, polymerase chain reaction (PCR) systems for accurately detecting, differentiating, and quantitating all of the genotypes and/or genogroups of TTV, TTMDV, and TTMV should be established and standardized, as should methods to detect past infections and immunological responses to anellovirus infections.

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Insertion of PSA and MARCKS-ED peptide into lipid bilayers from opposite sides alters the electric properties of the bilayer confirming the notion that PSA and the effector domain of MARCKS interact at and/or within the plane of the membrane. The practical application is demonstrated by the analysis of two case-control studies. A second bone biopsy, taken 6 months later, showed recovery of normal bone mineralization but the persistence of hyperparathyroid bone lesions. HLA antigens and antibody responses to measles and rubella viruses in multiple sclerosis. The Massachusetts Medical Society and the organization of public-health services-retrospect and prospect.

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Metallobacteriochlorophylls as potential dual agents for photodynamic therapy and chemotherapy. Organizational and operational capabilities of specialist centres for children with psychomotor disability in Abidjan. Our results document a wide range of substitution rates across genes and bacterial taxa.

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Adaptation of the Beck Hopelessness Scale as a suicide risk screening tool among Nigerian patients with schizophrenia. longicornis, and only a moderate portion of this is accounted for by larval substrate differences. Our results confirm that MAb EM-6E11 is suitable for detection of live cells but not heat-killed cells of Listeria spp.

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Selective cannulation of the anterior interventricular vein and coronary sinus: potential applications. Further genetic analysis demonstrated a cell-autonomous role for dTDP-43 in dendrite formation.

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We summarize current knowledge of how such extraordinary protein diversity arose and is maintained in microbial populations and what role these toxins play in mediating microbial population-level and community-level dynamics. Ramsey interference fringes in radiatively assisted collisions of K Rydberg atoms. The identification of one protein peak was confirmed via Western blotting. After test spots with increasing fluences (40-90 J/cm(2)) to determine the individual safe fluence, the maximum fluence of 90 J/cm(2) could be used in all 20 subjects. Two freely available resources make infobutton implementation possible for virtually any EHR system.

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Co-transfer of human wild-type p53 and granulocyte-macrophage colony-stimulating factor genes via recombinant adenovirus induces apoptosis and enhances immunogenicity in laryngeal cancer cells. Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis. Hence, bipolar disorder seems related to a greater emphasis on reaching goals and also a problematic reactivity to reaching those highly desired goals. Prenatal GC receptor activity is also increased during prenatal treatment with dexamethasone (DEX), which is commonly prescribed as a prophylactic treatment of preterm delivery associated morbid symptoms. Effects of antidepressant treatment following myocardial infarction.

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Microorganisms capable of contaminant degradation can grow in the matrix pores if the pores and pore throats are sufficiently large. Reliability of CO2 measurements from the airway by a pharyngeal catheter in unintubated, spontaneously breathing subjects. Human papillomaviruses (HPV) infect mucosal and cutaneous epithelium resulting in several types of pathologies, most notably, cervical cancer. Gene regulation in the vascular endothelium: why epigenetics is important for the kidney. The main indications for splenectomy were progressive transfusion-dependent anemia, painful splenomegaly, and hypercatabolic symptoms associated with cytopenia.

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Training programs for pharmacists including the accuracy of sphygmomanometers and regular checks of sphygmomanometers for accuracy will be beneficial to the community and to the subjects requesting measurement of blood pressure at the pharmacies. Specific periodontopathic bacterial infection affects hypertension in male cardiovascular disease patients. The usefulness of phase-based AIFs in clinical dynamic contrast-enhanced MRI (DCE-MRI) was investigated, and relevant pitfalls and sources of uncertainty were identified.

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Comparison between 2 different techniques of laparoscopic approach. A retrospective analysis was conducted of all cases of EPH performed at the RHW between the years 1999-2008 inclusive. The combination of different analgesics must be prescribed systematically, if there is no contraindication. The results suggest that YIGSR and IKVAV peptides specifically disrupt cell/extracellular matrix interactions required for normal development of the archenteron and feeding arms.

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The expression of GnRH receptor was assessed by the 125I-GnRH binding assay. Most cases have been treated with variable success using oral zinc, amino acids, and interferon with or without ribavirin therapy. We show that CL-V5B hamster mutant cells, a derivative of V79B, are hypersensitive to cisplatin-induced apoptotic death. Current criteria to predict low-risk prostate cancer (PCa) are still subject to discussion as a substantial number of PCa patients who progress to a more aggressive disease seem to be missed, using these criteria.

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The surgical steps of this technique and the related intraoperative images are reported. Using the DOP-PCR products of 1, Y1, Y2 chromosomes of M.m vaginalis as template respectively and the primers designed within human SRY HMG box, the Sry gene of the male M.m vaginalis was amplified, and it was cloned and sequenced. Immunohistochemical detection of Tritrichomonas foetus in formalin-fixed, paraffin-embedded sections of bovine placenta and fetal lung.

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In one animal where experimental testing was carried out, there was (as expected) no recovery of fine independent finger movements. However, further investigations of fluctuations in serostatus and of antibody levels for a more precise understanding of the predictive value are warranted. In concentrations of 100 micrograms/ml in platelet rich plasma Troxerutin significantly inhibited platelet adhesion to the extracellular matrix and siliconised glass as well as platelet spreading. To test this hypothesis we calculated phase synchronization between attention-related EEG source activations occurring between predictive directional cues and expected visual targets. Previous literature on the relationship between obesity and allergic disease has been inconsistent.

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Common variants in the regulatory region of the insulin gene are associated with fasting plasma insulin levels in juvenile obesity. Percentile growth curves for height and relative weight were constructed by using interpolated values from individual curves. Older people were less able to identify facial expressions of anger and sadness, and showed poorer ability to identify theory of mind from pictures of eyes. XBP-1 is also implicated in cellular de-differentiation, oncovirus infection and the epithelial-to-mesenchymal transition. A related toxin, LTIIb, binds to intestinal cells but does not cause toxicity.

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Effect of oral alanine loads on the serum triglycerides of oral contraceptive users and normal subjects. The control mechanism is discussed by analyzing the time- and frequency-resolved spectrum of the electric fields of the laser pulses. The triangle tilt surgery has been developed and shown to effectively address these deformities. The behaviour of the isolated rabbit renal calix and pelvis compared with that of the ureter. In contrast to dominant perspectives, being autistic was not considered a hindrance to aging well.

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Intervention should be multidisciplinary and multifactorial, targeting modifiable risk factors, especially for high risk patients. The aim of the study was to compare symptom response between the two treatment arms. A novel treatment processes of struvite with pretreated magnesite as a source of low-cost magnesium. In general, those residues that fall into the latter group are found to be invariant in kappa-neurotoxins and not found in alpha-neurotoxins. Hybridization and introgression in New World red mangroves, Rhizophora (Rhizophoraceae).

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More substantial benefits may require longer term and more intensive interventions which aim for more substantive lifestyle changes. The objective of this study was to develop and preliminarily validate a brief, patient-derived, disease-specific tool, the pancreatic cancer disease impact (PACADI) score. This C-H abstraction coupling technology has been successfully applied to the expedient synthesis of the medicinal agent haloperidol. In this form, this helminthosis is often self-limiting, leaving residual specific antibodies. The use of these strains as starters in a winemaking process could differently modulate the wine sensory characteristics.

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Simple statements of risks and benefits may not reveal the complexity of human responses to research participation. It was found that monocular enucleation changed the distribution of the evoked activity characteristically. It gave average and median size values which were compatible with the manual method.

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Results indicated that the permeability coefficient increased with increasing hydrophilicity of the molecule. Modified constraint-induced movement therapy versus traditional rehabilitation in patients with upper-extremity dysfunction after stroke: a systematic review and meta-analysis. The conclusion is supported by control experiments performed on a variety of single and multilayered Au nanoparticle structures, where only the hybridized oligonucleotides in a two- or three-strand system could be detected.

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The surgical therapy of jaw deformities in cleft lip and cleft palate. Selective reconstruction resulted in return of ESP-dsc in seven other patients. The MYB96 transcription factor mediates abscisic acid signaling during drought stress response in Arabidopsis. High-end graphics workstations (GWS) have been used for surgical simulators utilizing Computer Graphics (CG) and Virtual Reality (VR) technologies.

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In this well defined evolutionary scenario, we found that among all the properties of the protein interaction networks, it is the organization of networks into modules that seems to be directly related to the evolutionary process of genome reduction. A mechanism of erythrocyte shape control has been previously hypothesized in which Band 3, the anion exchange protein, controls the shape.

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The clinical and radiographic features are similar to the more common fibroadenoma, but the pathologic findings are diagnostic. Economic evaluation of a prerelease substance abuse treatment program for repeat criminal offenders. Effects of raloxifene on bone mineral metabolism in postmenopausal Japanese women on hemodialysis.

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Patients were then divided into two groups--those who were improved and those who were not improved by surgery--and mean MMPI scale scores were obtained for each group. Antisense oligonucleotides as well as expression of the antisense RB construct suppressed differentiation responses to ATRA or Vit D3, as judged by the capability to reduce nitro blue tetrazolium, by the appearance of monocyte-related cell surface antigens and by morphologic criteria. Impingment is a chronic syndrome characterized by microtrauma, which causes progressive injury to the rotator cuff tendon. In vitro effects of the tyrosine kinase inhibitor, masitinib mesylate, on canine hemangiosarcoma cell lines.