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Piramax (Topiramate)
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Topiramate

Piramax is a medication that works in the brain and is sometimes used in patients with bipolar disorder (also known as manic depression). It is approved for the treatment of seizures (epilepsy) in adults and children in combination with other anticonvulsants and for preventing migraine headaches in adults. Bipolar disorder involves episodes of depression and/or mania.

Other names for this medication:
Topiramate, Topamax, Epitomax, Letop, Neutop, Piramax, Talopam, Topamac, Topictal, Topigen, Topilex, Topimax, Topina, Topiramato, Topirol, Toplep,

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In patients with PP and suspected coronary artery disease, myocardial perfusion scintigraphy with Tc-Tf and stimulus with dipyridamole is of great value in the diagnosis of coronary artery disease and in the assessment of its extension. The thermodynamic parameters, obtained from the temperature dependence of the equilibrium binding constants, exhibit an enthalpy-entropy compensation with a favorable enthalpy at physiological temperatures. After 1 week these same individuals received a survey investigating these same issues as well as demographics and physical activity participation. We examined nationwide trends in TB and AIDS occurring in the same individual.

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A cysteinyl residue of peroxiredoxins reacts with the peroxides as primary catalytic center and oxidizes to sulfenic acid. Cloning of genes required for hypersensitivity and pathogenicity in Pseudomonas syringae pv. When patients underwent GKS as the primary treatment, it is known that dissecting tumor from adjacent nerves during salvage surgery is more difficult. The program builds on the concept of crime prevention through social development, and includes structured groups for the identified boy, parents, and siblings.

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The influence on the progression of atherosclerosis of an intervention on cardiovascular risk factors in HIV-infected patients remains unknown. Three years of strategy smooth occupancy of new hospital building. Data on mental health among injecting drug users in South Asia is scarce yet poor mental health among users has significant implications for the success of HIV prevention and treatment programmes. It has been established that anesthetic protection with alpha-1-adrenoblockers and alpha-2-adrenoantagonists of clofelin allows minimization of the postaggressive catabolic reactions of the organism, preventing severe impairment of homeostasis, reducing considerably the rate of intra- and postoperative complications and thus ensuring the favorable outcome of the operation.

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The 235-kDa antigenic rhoptry protein Py235 of Plasmodium yoelii is encoded by a large, highly polymorphic gene family. Effect of low-frequency electromagnetic pulses on the activity of natural killer cells of monocytes from human peripheral blood.

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The action of triethyl tin, triethyl lead, ethyl mercury and other inhibitors on the metabolism of brain and kidney slices in vitro using substrates labelled with 14C. There are no data on intrafamilial spread of HCV from India, where the family set-up differs from that in developed countries. Here we report the backbone and side chain (1)H, (13)C and (15)N resonance assignments for the cytoplasmic domain of human neuroligin 3. A dental health education campaign in a senior secondary school. The diesel fuel contained visible amounts of water, which caused vehicles that had been filled up with it to become defective.

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Coniopexic power of the reticuloendothelial system in aminonucleoside-induced experimental nephrosis. Screen time and physical activity during adolescence: longitudinal effects on obesity in young adulthood.

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This study demonstrates the natural healing ability of bone without any adjuvant filling. Regulation of drug metabolism in man by environmental chemicals and diet. Our results showed a statistically significant decrease in the total GST activity both in the small and large intestines of the mice infected with the nematode Trichinella spiralis (Owen, 1835) and treated with albendazole, compared with the control mice that were infected but untreated with the drug. Thromboxane analyses in patients with chronic inflammatory bowel diseases

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The proposed CS-HILIC-MS method enabled the simultaneous determination of reduced and oxidized thiols in mouse serum samples. This was finally reflected in reduced rates of newly synthesized triacylglycerols from de novo-derived fatty acids and decreased intracellular and secreted triacylglycerol concentrations in Fao cells treated with WY 14,643 and troglitazone, respectively.

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We examined the prevalence of residential development that occurs with consideration of the natural features of the site, known as conservation design, within county-level planning jurisdictions across Northern Indiana. Subjective assessment of peripheral perfusion with physical examination following initial hemodynamic resuscitation in the first 24 hours of admission could identify hemodynamically stable patients with a more severe organ dysfunction and higher lactate levels. It is shown that the technique is relatively robust to the choice of frequency and to the presence of noise. Additionally, perfusion scintigraphy yielded excellent localizing information and was reliable even in the presence of drug effect, conduction abnormalities and nonspecific electrocardiographic abnormalities. However PrP(Sc) was not amplified from the faeces of 25 sheep not exposed to scrapie.

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The triplet-triplet absorption and EPR spectra for the lowest excited triplet state of DHHB were observed in ethanol, while they were not observed in 3-methylpentane. Compared with the HBE cell line, expressions of SPRY4-IT1 in each human LA cell line had decreased, with the lowest observed reduction in the A549 cell line, while EZH2 mRNA and protein expression increased in each human LA cell lines. Deciphering the function of nucleic acid sensing TLRs one regulatory step at a time. Factors in all three solutions bore a strong resemblance to stress dimensions reported for the general population using other stress measures. These methods might be broadly applicable to the clonal analysis of tumor phenotypes in various organs in Drosophila.

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Theory of compositional and magnetic correlations in alloys: Interpretation of a diffuse neutron-scattering experiment on an iron-vanadium single crystal. Possibility of using modern factor analysis in social hygiene research Human perceptual learning in discrimination of the oblique orientation was studied using psychophysical methods. Sensitivity of cavity ionization chamber for fast neutrons and gamma-rays

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The infusion of citrate without calcium supplementation resulted in an increase in the bone formation marker OC and the bone resorption marker CTX, in addition to the changes in iPTH and iCa. The excluded mucin fraction was characterized by a high neutral hexose to protein ratio and contained all of the elasticity of thiocyanate-treated whole mucus. They also reported high compliance with recommended infection control procedures. A computer-controlled variable light attenuator for protection and autoranging of a laser-induced fluorescence detector for capillary zone electrophoresis. Patterns of gene expression in atrophying skeletal muscles: response to food deprivation.

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Therefore, our data suggest that LMP1 blocks p53-triggered apoptosis but not G1 arrest by upregulating bcl-2 expression. Following a standard development process, we could yield a design that meets clinical needs. Use of laser capture microdissection to selectively obtain distinct populations of cells for proteomic analysis. The hydroxylation of omeprazole correlates with S-mephenytoin metabolism: a population study.

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Central venous cannulation: A radiological determination of catheter positions and immediate intrathoracic complications. However, in most cases, it is a primary (idiopathic) disorder that reveals an abnormal handling of calcium by intestinal and renal tubular epithelia. Explicit conditions to improve the beam quality are provided, and the corresponding optimized beam-quality value that can be attained for a given field has been determined.

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High-resolution CT correlated well with pathology of the lung due to radiation injury as verified by precise radiologic-pathologic correlation. Corilagin was isolated from Phyllanthus niruri (Euphorbiaceae) by extraction and chromatographic procedures and the anti-hyperalgesic activity was evaluated by using writhing, formalin, capsaicin, glutamate and hot plate tests in mice. Compared to NC, svMCI patients showed cortical thinning in inferior frontal and orbitofrontal gyri, anterior cingulate, insula, superior temporal gyrus, and lingual gyrus, while cortical thinning in SVaD patients involved all these areas plus dorsolateral prefrontal and temporal cortices.

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We found that consuming 85.0-158 g/day of kimchi was significantly associated with a lower presence of AD. Its effects on long-term potentiation (LTP) in the Schaffer collateral/CA1 pathway were investigated using standard, extracellular recording techniques in rat hippocampal slice preparation. This suggests an increased frequency of IBF formation in cases with external fistulous tract closure. In biological systems, the predominant form of iron is the trivalent Fe(III) form, which is potentially not readily bioavailable because of its hydrolysis and polymerization to insoluble forms. The tightly controlled paracrine pathway that regulates oligodendrocyte precursor proliferation in the developing rodent CNS was constitutively active in most oligodendrogliomas in the present study.

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A 15 1/2-year-old girl with disseminated lupus erythematosus presented with acute flank pain and hematuria during oral anticoagulant therapy for thrombophlebitis of the lower extremities. Moreover, this technique can also be utilized for targeted delivery of drugs.

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Gene expression in Echis carinatus (carpet viper) venom glands following milking. Obstructive sleep apnea (OSA) is a medical condition with adverse consequences. Results indicated that salophen was both a colorimetric and fluorescent selective chemosensor for fluoride ion, which operated by the anion-induced conformational changes and subsequently excited-state intramolecular proton transfer (ESPT) process. Comparison of nanotube-protein corona composition in cell culture media. Their promoting activity is analyzed in term of synthesis of new cytochrome P-450 isoforms.

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The predicted secondary structure characteristics of the different domains of filensin suggests different functions for the two fragment sets to give filensin a dual role in the lens. Thrombosis is reduced by inhibition of COX-1, but unaffected by inhibition of COX-2, in an acute model of platelet activation in the mouse. Membrane lipid composition of cells in the nervous system is unique and displays remarkable diversity. Coronary angiography revealed an aneurysm 1.2 cm in diameter at the origin of the left anterior descending branch and confirmed the initial diagnosis.

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The gene cluster is organized into two oppositely orientated operons, lasAMNTUVPJW (lasA-W) and lasXY, the former of which contains the biosynthetic, immunity and transport genes. It seems reasonable to consider the combination of both as dangerous when we take into account that the majority of patients cited as having amiodarone-induced torsade de pointes had also potassium depletion. Multivariate dependencies between difficult childhood, temperament and antisocial personality disorder in a population of French male prisoners. administration of KM-110 suppressed tumour growth and inhibited the number of blood vessels oriented towards the tumour mass. Transient transfection assays showed that AREB6 repressed the human 70-kDa heat-shock gene promoter harboring the CACCTGT sequence together with the additional consensus, and that AREB6 activated the promoter harboring the CACCTGT sequence without the additional consensus.

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The effect of the pseudophakos in producing photochemical lesions is discussed. Immunohistochemically, tumor cells were positive for the follicular dendritic cell markers CD21, CD35, and CD23 and for S-100 protein, CD68, and muscle-specific actin. In a review of the relevant literature it is shown that happiness is statistically abnormal, consists of a discrete cluster of symptoms, is associated with a range of cognitive abnormalities, and probably reflects the abnormal functioning of the central nervous system.

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Follow-up of plasma endothelin and serum interleukin 2 receptor level after liver transplantation Other, less frequent patterns, which are nearly always focal, can also be found and hamper diagnosis: angiomatoid, fusocellular and clear cell. Results are compared with those obtained previously from a Bragg grating written into standard photosensitive fiber spliced to doped fiber. Analysis of variance and linear regression assessed for relationships between academic scores, chief resident selection, and gender to proficiency in ultrasound. Also, enhanced permeability effect of estradiol by using nanoparticle system and iontophoresis were observed in vivo.

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Current screening questionnaires do not accurately identify patients at high risk for OSA or rule out the presence of OSA in patients with CKD and ESRD. In this study, we want to determine the dipole estimation errors due to not taking into account the anisotropic conductivities of the skull and/or brain tissues. Individual case safety reports (ICSRs) are collected from broad patient populations and allow for the identification of groups of similar reports.

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The cystic fibrosis transmembrane conductance regulator (CFTR) Cl(-) channel is blocked by a broad range of organic anionic compounds. Both groups of patients were randomised in a treatment group (bezafibrate 400 mg daily) and in a control group. Molecular phylogeny and systematics of native North American lumbricid earthworms (Clitellata: Megadrili). Tissue-engineered small intestine (TESI) represents a potential cure for short bowel syndrome (SBS). Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI MSI) is a rapidly growing method in biomedical research allowing molecular mapping of proteins on histological sections.

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Myeloprotection conferred by GM-CSF may enable higher doses of chemotherapy to be given with only short intervals between cycles. Many studies confirm that psychological factors and burnout in physicians are interconnected. The lower apparent viscosities for highly concentrated protein suspensions relative to protein solutions, coupled with these favorable characteristics upon resuspension, may offer novel opportunities for subcutaneous injection of therapeutic proteins.

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We dissected the root cone into eight variables and used principal component analysis to summarize their correlation structure. How disoriented chiral condensates form: Quenching versus annealing. Particle interactions involved in aerosol dispersion of ternary interactive mixtures. EGCG is a potent inhibitor of cell proliferation, independent of EGFR inhibition, in several NSCLC cell lines, including those resistant to both EGFR kinase inhibitors and those overexpressing c-Met.

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Approximately one-third of the alleles causing genetic diseases carry premature termination codons (PTCs). Electron microscopy of mouse fibroblasts and immunofluorescence of KIF2beta-transiently-transfected fibroblasts show KIF2 and KIF2beta primarily associated with lysosomes, and this association can be disrupted by detergent treatment.

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These data suggest that arriving hydrophobic pheromone molecules are first bound by the reduced PBP and transported through the aqueous sensillum lymph towards the receptor molecules of the dendritic membrane. The nonhistone protein isolated from the porcine kidney functioned as a suicide substrate inhibitor for the furin-like enzyme. However, group exposure only potentiated MDMA-induced hyperlocomotion. There was a significant decrease in the cellularity of KO thymi, largely due to a loss of pre-selected DP cells, a decrease in DP cells undergoing positive selection, and a defect in SP maturation. Pressure-induced continuous phase transition of charge-density-wave state in a linear-chain complex.

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48 service users were recruited from secondary mental health services and their views on their personal goals and the meaning of recovery were explored in in-depth semi-structured interviews. After 4 weeks the pigs were killed, the heart was removed and subepicardial third-order branches of the left anterior descending artery were dissected and mounted in a myograph for morphological and functional assessment. Vasopeptidase inhibitors simultaneously inhibiting both NEP and ACE have shown to be more effective than currently available ACE inhibitors. NF-kappaB regulates androgen receptor expression and prostate cancer growth.

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A 32-year-old man with blurred vision in the left eye showed serpiginous choroiditis-like appearance. At least six topologically separated neurotoxin receptor sites have been identified on sodium channels that reveal strong allosteric interactions among them.

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Reproducibility and reference values of inclinometric balance and isometric trunk muscle strength measurements in Finnish young adults. A quarter century of the Minnesota Obstetrical and Gynecological Society. Change of cross-linked telopeptide of type I collagen (ICTP) and other bone resorption markers in patients with bone fragility fractures. MGMT methylation in diffuse large B-cell lymphoma: validation of quantitative methylation-specific PCR and comparison with MGMT protein expression. The relative dearth of research attention on school drop-out prior to first treatment contact in young adults with psychotic disorders indicates a need for investigation of the associations between school drop-out and illness-related variables so that interventions may be tailored appropriately to this unique population.

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This systematic review aimed to evaluate the efficacy, morbidity and mortality of laparoscopic peritoneal lavage for patients with perforated diverticulitis. All patients were followed up from 4 to 7 years with an average duration of 75.3 months. ICE chemotherapy was tolerable and active against medulloblastomas.

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F VII levels increase in patients with previous coronary events, but it is not an independent risk factor for the progression or for the severity of CAD. Estrogen influences auditory brainstem responses during the normal menstrual cycle.

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Optimising azathioprine treatment: determination of thiopurine methyltransferase activity and thiopurine metabolites Is the peptic-tryptic decomposition of gliadin of antigen character? This report shows that norclozapine but not clozapine-N-oxide has the same D2 receptor affinity as clozapine. At the moment, phosphodiesterase type 5 inhibitors are claiming their position in the armamentarium of BPH treatment.

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Changes in the functional state of the brain in children following a course of transcutaneous electric stimulation of the visual analyzer That is, SpCD errors from the MPD not only showed significantly higher negative rs with the criteria (reading vocabulary, reading comprehension, and mathematics computation) than Koppitz errors from the Bender, but also accounted for a much higher proportion of the variance in these criteria. Special attention is given to papers on foot deformities at initial stages of the disease. TKA components that reduce patellar loads and preserve physiological patellar kinematics should reduce these problems.

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Viral hepatitis C in patients with terminal chronic renal insufficiency. This was followed by a saphenous vein graft between the left subclavian and the internal carotid artery. Fifty-six women with GSI were evaluated in a urodynamics laboratory.

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Temperature dependence of the Hall angle in single-crystal YBa2(Cu1-xCox)3O7- delta. A simple breeding protocol for the procurement of accurately staged rat donor embryos for neural transplantation. Means of manufacturing platinum microcathodes with a mirrored operating surface Circulating immune complexes in the blood serum and cerebrospinal fluid of meningitis and meningoencephalitis patients

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We used brain blood oxygen level dependent fMRI to study the neural responses to tasks targeting ToM and Emp. Transcript levels of 11 genes, determined by quantitative RT-PCR, were highly correlated with the microarray data.

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Design of injectable organic-inorganic hybrid for bone tissue repair. Understanding and preventing relapse to drug use is one of the most difficult challenges faced by clinicians and practitioners in the struggle to help people remain abstinent.

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Black oxytetracycline sale p kulit 88 patients were older, with more relapses and motor impairment. Pitfalls in using agarose gel electrophoresis as the sole method for the identification of apoptotic cells are discussed. Incubation of human keratinocytes with 50 microM of acrolein induced atypical apoptosis with morphologic apoptotic features with low-grade oligonucleoside-sized DNA fragmentation.

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In the 20 fetuses with ectopic beats, arrhythmia was observed postnatally in 10, but all of these were resolved within 3 months after birth. Functional characterization of mutants of the diatom Phaeodactylum tricornutum, in which the aureochrome genes have been silenced or deleted, indicate that different aureochromes may have different functions, being involved in central processes like light acclimation and regulation of the cell cycle. The assumption cravit ophthalmic solution 5ml to teaspoon that mammalian submaxillary kallikreins are identical proteins is questioned.

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A dose-response study of nitric oxide synthase inhibition in different vascular beds in man. Myocardial ischemia caused by coronary arterial compression by an aneurysm of the sinus of Valsalva is a particularly unusual complication. Unexpectedly, the proportion of cortex and medulla in the NZB mice was normal from 36 wk, despite worsening architectural abnormalities. To determine trifamox ibl suspension 30 ml syringe the effect of treatment with recombinant human granulocyte colony-stimulating factor (rhG-CSF) for puppies with neutropenia secondary to canine parvovirus infection.

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When the exponent of the in-degree distribution is larger than 3, we obtain results equivalent valacyclovir dosage oral herpes to those obtained for networks with fixed in-degree, e.g., the number of the nonfrozen nodes scales as N(2/3) with the system size N. These results indicate that the rat lymphocyte/Hprt assay is useful for detecting chronic low level exposures. Accordingly, a cytochrome P450 monooxygenase in the 2C family was cloned from an equine liver, sequenced and expressed in a baculovirus expression system. There were few differences between smokers and never smokers for total energy intake, energy from total and animal protein, monounsaturated fats, PFA, omega 3 and omega 6 PFA, dietary cholesterol, total vitamin A, retinol, vitamin D, vitamin B12, and urinary and dietary Na. Strategies for overcoming these effects are described with particular reference to their application in embryonic stem cells.

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Drug benefits have responded to the rise in drug costs by increasing patient cost sharing. Because HSF1 is also the target flucon spray factor for metabolic and environmental stress, these data reveal an intersection of pathways leading to HSF1 activation. In cases of exposure to unknown substances, analyzing environmental or biological samples for elevated levels of toxicants can be extremely complex. Morphological evidence for a possible functional role of supra-ependymal nerves on ependyma. Ninety patients undergoing cardiac surgery with cardiopulmonary bypass were randomized to receive either morphine (40 mg) or fentanyl (600 mug) as part of a standardized opioid-isoflurane anesthetic.

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The structure and function of bisphosphonates, and their role in the development of BRONJ will be discussed, as will the possible mechanisms through which this pathology develops. One limitation was that no reference standard existed for some components, limiting some aspects of validity assessment. To define the allopurinol side effects headaches pharmacokinetics of continuous infusion pralidoxime in organophosphate-poisoned children. These agents have shown diverse propagation pathways based on their own molecular pathogenesis, physiology, taxonomy, and etiology.

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