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Curative effects can be increased by combining the use of TCM with Western medicine. Basal as well as 2,3,7, 8-tetrachloro-p-dioxin-induced promoter activities are strongly impaired by H2O2 treatment or glutathione depletion with L-buthionine-(S,R)-sulfoximine. This patient population also had significantly increased plasma markers of lipid peroxidation compared with normal subjects. Passive signal processing of two signals in quadrature is used to obtain the vibration amplitude with a resolution of approximately 0.1 nm. Comparison of reverse transcription-quantitative polymerase chain reaction methods and platforms for single cell gene expression analysis.

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On the other hand, low-dose nC(60) (0.25 microg/ml) did not induce either necrotic or apoptotic cell death, but caused oxidative stress/ERK-independent cell cycle block in G(2)/M phase and subsequent inhibition of tumor cell proliferation. The haematological abnormalities of early CS are variable and non-specific, and can mimic several haematological diseases of infancy.

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Use of the eximeric laser for removal of atherosclerotic plaques We describe a new scoring method and show its sensitivity to treatment with clonazepam. In particular, there is an urgent need for high-quality descriptive research, including prospective cohort studies, as well as randomized controlled trials to define optimal management strategies. Effects of heat-exercise stress, NBC clothing, and pyridostigmine treatment on psychomotor and subjective measures of performance.

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We developed a clinical intervention, the Clinical Preceptorship Program (CPP), for MD/PhD students at Vanderbilt to ease the transition to the core clinical clerkship year (the 3rd medical year) following graduate training. Additionally a shell of scatterers at 0.37 nm (3.7 A) was observed in both states which could be fitted to models with calcium scatterers at this distance. In the model peptide Z-Pro-NHMe, the amide I and II bands in the 1500-1800 cm(-1) region appear to be a clear diagnostic for the secondary structure of the backbone, while the analysis of a series of coupled CH bending modes in the 1000-1500 cm(-1) region allows to distinguish between different possible orientations of the chromophore.

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For the same reason, they have been suggested for trapping and tweezing applications. Chemokines and adhesion molecules such as integrins play a major part in the trafficking, extravasation, and recruitment of leukocytes to inflammatory sites. Stress responsivity and socioeconomic status: a mechanism for increased cardiovascular disease risk?

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Safety, efficacy, and pharmacokinetics of balsalazide in pediatric patients with mild-to-moderate active ulcerative colitis: results of a randomized, double-blind study. This meta-analysis included 8234 patients with kidney disease from nine qualified randomized trials using folic acid therapy, and with CVD reported as one of the endpoints. A spontaneously ruptured gastric stromal tumor presenting as generalized peritonitis: report of a case. Sleep disturbances in young and middle-aged adults - Empirical patterns and related factors from an epidemiological survey.

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The task of assigning resonances in proton nuclear magnetic resonance spectra of paramagnetic heme proteins can be an arduous process, but with the development of multi-dimensional NMR methods the situation has improved. So, identification of tumor markers and a method for early diagnosis using such markers are urgently needed. Complement components C5b-6 and C7 assemble to form C5b-7, which then interacts with membranes and commits the membrane attack complex to a target site. MAK-4 and -5 supplemented diet inhibits liver carcinogenesis in mice. A marked thermal hyperalgesia was observed in response to heat stimulation applied to the operated side from 3 days through 2 weeks, followed by a gradual return to the control level 35 days after surgery.

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It also has the unique ability to convert sugars to electricity, oxidizing the sugars to carbon dioxide with quantitative electron transfer to graphite electrodes in microbial fuel cells. This study demonstrated that once a day administration of everolimus achieved excellent patient and graft survival and good renal function without an increased incidence of acute rejection episodes. Treatment of acute and transient psychotic disorders with low and high doses of oral haloperidol. In addition, we argued that a theory about the attribute may guide the researcher but that well-tested theories are often absent. Abnormal mobility shifts in single strand conformational polymorphism (SSCP)-analysis of exons 2 and 3 of the p53 gene in 2 out of 5 medullary thyroid cancers (MTC) prompted us to sequence the corresponding genomic region spanning codons 9-32.

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Investigation techniques for karst flow systems are based mainly on the study of different signals leaving the system caused by natural or induced external influences. Because of methodological limitations, results of behavioral interventions are inconclusive.

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The stem cell concept of tumour progression prompts immediate attention to a new paradigm in cancer research with a focus on this minority subset of cells, and the design of novel therapeutic strategies to target these cells that are insignificant within the population of tumour cells, but that are in fact the relevant cells to be destroyed. In our work an example of new-born female with this syndrome is reported, and a review of 136 cases from the literature is presented. It remains unclear whether normal cellular protein targets of chemotherapeutics will evolve drug resistance via mutation to a similar extent. Dehalogenation of dichloroethene in a contaminated soil: fatty acids and alcohols as electron donors and an apparent requirement for tetrachloroethene. Inhibition of 11 beta-HSD with glycyrrhetinic acid allowed cortisol to gain direct access to the fetal circulation.

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The aim of this review is to provide an update on the progress made in the development of the magnetic targeting technique addressing characteristics of the magnetic carriers and limitations of the current targeting magnet systems. To determine the effectiveness of three different local injection modalities in the treatment of lateral epicondilitis. Relatively little is known about selenium embryotoxicity in zebrafish.

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To establish a prescription opioid registry protocol in a large health system and to describe algorithms to characterize individuals using prescription opioids, opioid use episodes, and concurrent use of sedative/hypnotics. Rectus abdominis flap due to its pliability and long pedicle proved to be most suitable flap together with superficial temporal artery and vein as recipient vessels.

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Controversies including the use of dental implants in irradiated tissues, and hyperbaric oxygen treatment will also be discussed. Sixty-nine and 67 out of 147 throat washings taken from patients during the period from January to April 1994, were positive for influenza A virus in HeLa cells and MDCK cells respectively. The efficacy of antimicrobial titanium appears to be based on peroxidation, since peroxidation products were detected in parallel with the destruction of bacterial cell-surface structures.

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Effectiveness of silver diamine fluoride and sodium fluoride varnish in arresting dentin caries in Chinese pre-school children. Fourteen domestic pigs underwent cholecystostomy tube placement and cystic duct ligation. The chemotactic responses towards serum from the uremic patients were significantly decreased (p less than 0.01) prior to hemodialysis compared to control serum from a healthy individual. Treatment consisted of parenteral administration of fluids and antibiotics. Stability of ifosfamide in solutions for multiday infusion by external pump.

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Two population-based studies of neuromyelitis optica (NMO) in non-white populations provided prevalence rates of 0.32 and 3.1 per 100,000 population. Accumulating data implicate PTKs as essential intermediates in the transduction of extracellular signals to the interior of the cell. The potential benefits, risks, and clinical use of bedside monitors of aspiration are under increasing scrutiny.

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ERM proteins also play a role in the Rho and Rac signaling pathways: activated ERM proteins can dissociate Rho-GDI (GDP dissociation inhibitor) from Rho and thereby activate Rho-dependent pathways. An analysis of the oleosin secondary structures reveals an N-terminal amphipathic domain, a central hydrophobic anti-parallel beta-strand domain (not found in any other known protein), and a C-terminal amphipathic alpha-helical domain. We were able to localize the electrode array within the scala tympani within the basal turn in 10 implants.

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These results point out the possible role of the dentist in the early diagnosis of osteoporosis. In this magnetoencephalography (MEG) experiment, we tested whether N1m MEG responses, previously described to scale with sound intensity, are modulated by visual distance cues. Surveillance rates and clinical data were extracted from the patient electronic medical record. The diagnosis of SOM required the detection of effusion behind the tympanic membrane in association of air-bone gap of 10 dB or more in pure tone audiogram.

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Reversible stepwise mechanism involving a carbanion intermediate in the elimination of ammonia from L-histidine catalyzed by histidine ammonia-lyase. There has been one case in the literature of EM following Rhus contact dermatitis. The opinion poll of the parents who used child resistant package The availability and widespread use of TPN enables physicians to help patients in a way that had not been possible in the past.

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Tocilizumab inhibits structural joint damage and improves physical function in patients with rheumatoid arthritis and inadequate responses to methotrexate: LITHE study 2-year results. Such regions of the composition x - T phase diagrams provide the conditions for minimal anisotropy with respect to the direction of the polarization, so that the polarization can easily rotate maintaining a substantial magnitude, while the near verticality of the TMPB(x) boundary extends the temperature range of the resulting enhanced piezoelectricity. Expanded transposition flap technique for total and subtotal resurfacing of the face and neck. It is used to evaluate in vivo radiation over-exposure and to assess in vitro chromosomal radiosensitivity. Inter-individual difference determinant of prednisolone pharmacokinetics for Japanese renal transplant recipients in the maintenance stage.

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Compared with devices utilizing sheath flows, the focusing patterns generated in this report are unique without introducing additional flow control. Appendiceal diverticulitis is a distinct entity with several clinical and pathological differences from acute appendicitis. This study investigated the effects of long-term statin treatment before elective PCI on coronary plaque composition at the angiographically severe target stenotic lesions. ADMA might be a novel clinical and experimental biomarker related to gastric mucosa disorder. We conclude that musclin binds to NPR3 competitively with ANP and may affect ANP concentrations in a local or systemic manner.

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Human lung fibroblasts (fetal, adult and idiopathic adult pulmonary fibrosis) were treated with transforming growth factor (TGF)-beta 1 with or without SAHA. Stingray venom is unique in its enzymatic composition and results in distinct soft tissue injury patterns. We conclude that retinoic acid exerts its control over expression of the EGFR in H460a cells through a posttranscriptional mechanism.

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These mutant RNAs sequester the splicing regulator Muscleblind-like-1 (MBNL1), resulting in specific misregulation of the alternative splicing of other pre-mRNAs. This study finds that youth will accept computerised screening if the system is perceived to be useful and easy to use. Complete cocaine-choice dose-effect curves (0-1.0 mg/kg/infusion) were obtained for each condition under concurrent fixed ratio schedules of reinforcement. By using the method developed in our work, the location and identification of two different isoforms of the allergen Ara h 1, the allergen Ara h 2 and six isoforms of the allergen Ara h 3/4 in 2D peanut protein maps was established.

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Celiac disease is associated with an increased risk of autoimmune diseases (type 1 diabetes, thyroiditis), and cancer (upper digestive tract, hepatocellular carcinoma, lymphoma). The purpose of our study was to estimate the value of CT angiography in the detection of intracranial aneurysms.

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Clinical features of Japanese family with autosomal dominant retinitis pigmentosa caused by point mutation in codon 347 of rhodopsin gene. The aim of this study was to investigate the possible effects of YTX on the other contractile striated tissue, the skeletal muscle, in vitro and in vivo. Role of the follistatin gene in women with polycystic ovary syndrome. Our purpose here is not to advocate for a new density functional, but to explore a previously published idea. Drive level (D) and extinction in classical aversive conditioning.

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The MSLT and MWT should not be used for the assessment of workplace safety. These results lend support to the efficacy of bortezomib in the treatment of plasmacytoma. Effect of SR 33805 on arterial smooth muscle cell proliferation and neointima formation following vascular injury. Movement-related neuronal activity was identified by imposing passive ramp and hold stretches of the jaw at four different rates. Uncovering the strategies of green development in a Chinese province driven by reallocating the emission caps of multiple pollutants among industries.

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We show that the NARM-induced sampling matrix is less coherent with the representation dictionary, and consequently makes SRM more effective for image interpolation. From these results, we conclude that salinity can play a significant role in modulating the activities of enzymes acting on lipid metabolism during their natural circannual cycles.

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Forty-eight tinnitus patients were randomly assigned to one of three groups: counseling, counseling plus bilateral noise generators set to completely mask the tinnitus, or counseling plus bilateral noise generators with a focus on the mixing point (partial masking just below total masking). A key to success is the strategic selection of teeth for retention. The most discriminating peak of 15.9 kDa in plasma in a testing group of eight patients with delirium to eight patients without delirium was confirmed in an independent validation group. PL plus ISO lowered the LD50 of ISO and magnified the changes in heart rate, ECG and myocardial electrolytes seen with ISO alone. The results of this study suggest that the mid-metacarpal region of the SDFT, although smaller in CSA, is not significantly weaker than the proximal end and manica flexoria region of the tendon.

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Moreover, the impact of this infection on the outcome of the hematologic disease needs to be better defined. Tumours of the spine occasionally also present with an intra-thoracic extension.

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A pooled analysis of arc-based image-guided simultaneous integrated boost radiation therapy for oligometastatic brain metastases. The current combined active membership of the two societies was analyzed to determine the impact of age distribution on this model. Combination of irinotecan and etoposide for treatment of refractory or relapsed small-cell lung cancer.

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In this study, we report the radiosynthesis and in vitro and in vivo evaluation of 11C and 18F sulfonamide derivatives targeting carbonic anhydrase II (CA II), a metallo-enzyme expressed in RBCs, as potential blood pool tracers. Newer stent designs and anticoagulant regimens may alleviate some of the current concerns with regard to stenting at the time of acute myocardial infarction. mRNA levels of gamma- and beta-casein are similar in lactating mammary tissue. In the present study, we report that NIP2, previously identified as centrobin, is a novel substrate of Nek2. The ERECTA gene controls spatial and temporal patterns of epidermal cell number and size in successive developing leaves of Arabidopsis thaliana.

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We report a patient who underwent, over a mere 3-year period, three successive cycles of oscillation from hypo to hyper-thyroidism and back to hypothyroidism. This system provides a valuable tool for generation of iPS cells, and our data suggest that the balance of expression of transduced reprogramming TFs in each cell is essential for the reprogramming process. Furthermore, the development of cell culture systems that use primordial follicles as a source of oocytes for in vitro growth and maturation will enable us to maximize the potential of high genetic merit females and to shorten generation intervals.

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The authors describe an original technical modification of the extensor digitorum brevis muscle flap. To record somatosensory evoked potentials (SEPs) to median nerve stimulation by chronically implanted electrodes in the parieto-rolandic opercular area of 9 epileptic patients, in order to evaluate whether somatosensory evoked responses could be generated in the second somatosensory area (SII) earlier than 40 ms after stimulus.

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Ten patients were identified with FLD, seven females and three males, with mean age of 25.9 years at diagnosis (range, 10-59 y). Impact of different brain protection techniques upon postoperative temporary neurological dysfunction in aortic surgery with the aid of deep hypothermic circulatory arrest

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The inhibition was dose-dependent and was coupled to an inhibition of the cyclic GMP production activated by L-arginine. The literature supports the binaural benefit of bilateral cochlear implantation with demonstrated improved speech perception outcomes in quiet and in noise, sound localization data, and subjective benefits. The broad diversity of neutral and sialylated oligosaccharides derived from human salivary mucins.

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Intravascular perfluorochemical emulsions together with a high oxygen tension may increase the delivery of dissolved oxygen to useful levels. For this purpose, such data must be extracted and restructured appropriately. Hearing loss was examined in 46 individuals from 24 families who were either homozygous or compound heterozygous for Cx26 mutations. Meanwhile, clinicians can use the findings of this study to derive their own judgments. If fibrosis develops around a BAP device, then the permeability of substances transmitted through a semipermeable membrane will decrease, thereby reducing the reactivity with glucose, so it is necessary for the material of the device to have an excellent histocompatibility.