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PIT1 abnormality is defined as a genetic abnormality in the PIT1 gene, which encodes a pituitary specific transcription factor Pit-1/GHF-1.PIT1 abnormality has been reported in several patients displaying either complete or incomplete deficiency of thyrotropin (TSH), growth hormone (GH), and prolactin (PRL) in either familial or sporadic cases. The important implication of these investigations is that patients with acute myocardial infarction who are treated with platelet anti-aggregatory agents prior to revascularization may already be in a postconditioned state. The weaker correlation between capillary perfusion and capillary compression in DWB-reperfused hearts suggests that factors other than compression contribute to no-reflow after hypothermic preservation. In addition gel retardation experiments indicated that RTG1 does not bind to the ORE.

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The existing incident management system questionnaire used for evaluating Command and Control during a disaster exercise would benefit from minor adaptations and validation that could not be anticipated in the exercise planning stage. In the present study, pork meat as the experimental subject was equally divided into three pieces. A smaller decrease was observed for folic acid at 1 year of storage, but the level remained constant thereafter. After the appearance of erythema, the skin and mucous membrane lesions progressed rapidly and spread over the entire body, even after the patient ended methazolamide treatment and started treatment with prednisolone.

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Populations in the study region are not endangered, and current population dynamics are stable. Ciliated sensory papillae are concentrated around the oral sucker.

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However, in addition to pharmacological therapy intensive pharmaceutical care is crucial for COPD patients. Incomplete circumferential osteotomies were then performed around each magnet on 13 of the rabbits. To determine if preoperative patient verbalization of the risks and benefits of anterior cruciate ligament (ACL) reconstruction enhances understanding of the risks and benefits of that procedure. Frequent emergence of N348I in HIV-1 subtype C reverse transcriptase with failure of initial therapy reduces susceptibility to reverse-transcriptase inhibitors. Our data suggest that nitroglycerin induces regional changes in CBF that are similar to changes reported in spontaneous migraine, but produces distinctly different effects on global CBF and velocity.

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The methacholine bronchoprovocation model is safe and useful in the study of albuterol MDI dose-response in asthmatic subjects. Myocardial work (heart rate x systolic blood pressure), myocardial lipid content, oxidative and antioxidant enzyme activities (citrate synthase (CS), catalase (CAT), glutathione peroxidase (GPX), superoxide dismutase (SOD)), the rate of papillary muscle superoxide radical production in vitro, thiol content, basal and post-oxidative challenge myocardial lipid peroxidation levels using thiobarbituric reactive acid substances (TBARS) and lipid hydroperoxides (PEROX) as indices of lipid peroxidation.

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Changes in the shape of the gait loop are primarily determined by changes in the coupling between the thigh and shank elevation angles. Excessive tissue repair can lead to problems such as scarring and organ fibrosis and adenosine, and its receptors play a role in pathologic fibrosis as well. Most patients also require simultaneous drug therapy, with the potential risk for drug-nutrient interactions which may become relevant in clinical practice. To investigate the expression of CXCL12, its receptor CXCR4 and its correlations with clinical pathology and lymphangiogenesis in pancreatic adenocarcinoma (PAC).

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Low-loss thin-film LiNbO(3) optical waveguide sputtered onto a SiO(2)/Si substrate. Our goal was to determine whether maternal asthma and maternal smoking during pregnancy are associated with the incidence and severity of clinically significant bronchiolitis in term, otherwise healthy infants without the confounding factors of small lung size or underlying cardiac or pulmonary disease. brucei gambiense transformed from either HSS or HSR bloodstream stages were found to be HSR. At dosage of 32 mg/wk, all birds became severely ill and either died or were euthanatized within 2 weeks.

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Three MDR-related molecules, taken as models for interaction with P-glycoprotein, appear thus to bind on at least two different separated specific sites. Mutation screening of the RYR1 gene and identification of two novel mutations in Italian malignant hyperthermia families. In order to achieve microscopic chemical imaging with enhanced quantification capabilities, the current study links the independent and complementary advantages of two micro-analytical techniques - Synchrotron Radiation-based micro X-ray Fluorescence (SR-microXRF) and Laser Ablation Inductively Coupled Plasma Mass Spectrometry (LA-ICPMS). Pharmacognostical studies on cortex Indigoferae Pseudotinctoriae As CF lung disease progresses, children and their caregivers are often simultaneously preparing for lung transplantation and end of life.

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This study was conducted on forty male patients aged 17-35 years, suffering from migraine. 35 ALTE infants were studied with nighttime polysomnography at 2-3, 5-6, and 8-9 months of age. Water permeability and its activation energy for individual hamster pancreatic islet cells. Subacromial space width decreased with shoulder elevation, ranging from 2.3 to 7.4 mm in the repaired shoulder and 1.2-7.1 mm in the contralateral shoulder. The effect of recent advances in critical care and the emphasis on early fracture fixation in patients with fat embolism syndrome (FES) are unknown.

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There is extensive variation in gene expression among individuals within and between populations. In the second group, it is the slowest relaxation mode which is implicated in the oscillations so these can be very lightly damped. There were seven uncleaved glycoproteins with a pH optimum of 5.2, relatively low specific activity (278 U/mg) and differentially sialylated. These results suggest that SRBFS promoted osteoblastic differentiation of BMSCs in vitro and in vivo, and demonstrate feasibility as a bone engineering scaffold.

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Our major outcome measures were the number of oocytes obtained and ongoing pregnancy. This corrosion is concerning, because a large amount of metal ions and debris are generated in this process, the accumulation of which may lead to adverse tissue reactions in vivo. Recent findings have suggested that the Simon effect can be strongly modulated by prior practice with a spatially incompatible mapping and by correspondence sequence. Furthermore, there was a tendency towards higher surprise ratings when the unexpected event deviated from a strong connection, indicating that the discrepancy is more severe. This program of research integrates clinical research (in the areas of acute respiratory illness and injury) and knowledge translation (KT).

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These findings suggest a potential role for CPFA in the treatment of MODS. The authors therefore have established an animal model with single versus multiple exposures of anesthetic(s) in young versus adult mice, aiming to distinguish the role of different types of anesthesia in cognitive impairment.

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This study of Cidaris blakei, a deep-sea cidaroid urchin with planktotrophic larvae, provides a description of development from fertilization through early juvenile stages and is the first report of a deep-sea urchin reared through metamorphosis. On the effect of cooling on the function of respiration in cold-blooded vertebrates Compressive strength, rotational movement, resistance to cyclic loading and torsional strength were evaluated.

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Cadmium, a toxic heavy metal, expresses its toxicity by affecting several cellular functions, such as enzyme activities, DNA repair systems, redox state of the cell and signal transduction. Adeno-associated virus (AAV) vectors have significant potential as gene delivery vectors for cancer gene therapy.

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High sensitivity of positrons to oxygen vacancies and to copper-oxygen chain disorder in YBa2Cu In intertemporal decision making, individuals prefer smaller rewards delivered sooner over larger rewards delivered later, often to an extent that seems irrational from an economical perspective. Patients were then transferred to the magnetic resonance OR to check the completeness of the resection. This study is undertaken in order to find out (a) whether increasing the dose of nebulized furosemide from 1 to 2 mg/kg of body weight will further improve the pulmonary mechanics in premature infants with evolving chronic lung disease and (b) whether the effects of a single dose of nebulized furosemide last beyond 2 hours.

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Invasive non-typhoidal salmonella disease: an emerging and neglected tropical disease in Africa. A massive accumulation of C-shaped parasites in various visceral organs was found post-mortem.

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Correlations among somatic cell scores of milk within and across lactations and linear type traits of Jerseys. However, in kidneys collected at E20.5 after in vivo exposure for 2 days, GDNF expression was increased and BMP-4 and TGF-beta1 expression decreased suggesting a biphasic response in gene expression to DEX exposure. Targeting the Notch pathway: twists and turns on the road to rational therapeutics. Intracranial arterial wall imaging using high-resolution 3-tesla contrast-enhanced MRI.

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Detection of QTL in multiple segregating families possesses many advantages over the classical QTL mapping in biparental populations. This article presents a case of pure posterior subtalar dislocation in an 80-year-old man who presented with pain and deformity in his left ankle following a motorcycle accident. A few isolates were also obtained from blood, cerebrospinal fluid, and miscellaneous tissues.

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The oyster MXR system is thus becoming active in adult oyster and could be of importance in environmentally contaminated areas. Clearances across standard and HCO filters using continuous or intermittent RRT are reviewed in a case series of 11 patients with severe rhabdomyolysis and dialysis-dependent AKI.

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To investigate the mast cell stabilization and antihistaminic activities of the rhizomes of Curculigo orchioides (COR). Results showed that both participants significantly increased their time duration of maintaining upright head position (TDMUHP) to obtain the desired environmental stimulation during the intervention phases. No distinct immunoreactivity was found in the retinal pigment epithelium. Normalized IBDV antibody concentrations were used in neutralization assays against homologous and heterologous IBDVs in 10-day-old specific pathogen free embryos. In 28 patients with SAR and 50 healthy study patients, the leukotrienes were measured in EBC during and after the pollen season by gas chromatography/mass spectrometry.

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Observed dose-response curves were compared to those predicted from concentration-addition and independent-action models. Intellectual development of at-risk children--results of the Rostock longitudinal study after 10 years Given the common morphological features seen in human PNH and MAM-induced brain heterotopia, the anatomical and developmental analysis of MAM-treated rats may shed light on the mechanisms by which human brain dysgeneses develop in human patients. pylori-infected and -uninfected gastric mucosa and to elucidate the implication in the pathogenesis of HAG in humans.

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Do anesthetics act by competitive binding to specific receptors? The results were compared with control hamsters (F1B) of the same age. Increase of ventricular output inducing ventricular afterpotential sensing and ventricular safety pacing in a biventricular implanted cardioverter defibrillator.

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The active OPN-501 generated a stoichiometric amount of prednisolone following azoreductase activation, whereas its analogue did not. The growth of UECs in cell-scaffolds was assessed by scanning electron microscopy, immunohistochemical and fluorescence staining. Drug eluting antimicrobials have an inhibitory effect on bacterial adherence and the Polaris stent showed the least bacterial adherence of the nondrug eluting ureteral stents tested. New type of periodic long-range restructuring of ordered metal surfaces induced by lateral adsorbate interactions: Iodide on Au(110) electrodes. Neoplastic cell lines exhibit RNA synthesis and process patterns which are related to phenotypic attributes more complex than merely the rate of proliferation.

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Autonomic arousals in sleep related breathing disorders: a link between daytime somnolence and hypertension? Our FFQ yielded substantially high reproducibility and it may be applicable for assessing consumption of foods/food groups and energy and selected nutrients for the middle-aged and elderly population in Japan. To compare dietary intakes of Maori, Pacific Islands and European men and women in New Zealand.

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Because attractiveness is supposed to consist of medical demand and the amenities of urban life, the two parameters may represent the amount of medical demand and/or the extent of urban amenities of the community more precisely than population does. The applications of a pulse oximeter were studied in dental day case surgery using nasal mask anaesthesia.

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The aim of this study was to assess risk factors for SSI in laparoscopic sigmoid resection for benign disease. Is the use of donor sperm associated with a higher incidence of preeclampsia in women who achieve pregnancy after intrauterine insemination? A total of 245 new pressure ulcers occurred between admission and patient observation. Influence of stent height upon stresses on the cusps of closed bioprosthetic valves.

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Here we present 10 newly developed microsatellite loci for this tsetse species. From the nutritional standpoint, the right combination of plant proteins can supply sufficient amounts of essential amino acids for human requirements. On the Michael type addition of cyclic hydrazides to activated vinyl groups Aim of this study was to measure plasma levels of nine molecules involved in these vascular processes in a group of SSc patients, respect to healthy controls (NC).

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Maternal NVP resistance at 6-8 weeks did not predict late transmission. This method may facilitate positioning of the beam isocenter and provide reliable conformal radiotherapy. Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) is a member of the tumor necrosis factor superfamily of cytokines. It is pointed out that the conclusion often drawn on the basis of such research, that there is little or no relationship between eyewitness confidence and accuracy, is an unwarranted generalisation based on the use of experimental paradigms that are limited in terms of their generalisability to courtroom situations.

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Macrophages from galectin-9-treated mice produced less TNFalpha and IL-1 beta but more IL-10 than PBS-treated mice. When titanium is anodized by discharge in NaCl solution, both antimicrobial activity and osteoconductivity are conferred.

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Adjusted for age, and race/ethnicity, young adult obesity status explained a small, but statistically significant amount of height growth among both females and males within each of the three intervals. These offsets are in accordance with the experimentally observed theta wave traveling from the dorsal to the ventral pole of the hippocampus.

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