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The protective effects of silymarin and silibinin, demonstrated in various tissues, suggest a clinical application in cancer patients as an adjunct to established therapies, to prevent or reduce their toxicity. While nine children showed IgG4 levels below the level detectable by the technique used, it is not possible to assess whether these patients are deficient in this isotype since some healthy subjects also give values below the level of detection. Tissue distribution, hormone regulation and evidence for a human homologue of the estrogen-inducible Xenopus laevis vitellogenin mRNA binding protein. Average levels of ingestion of currently known mycotoxins in most EEC countries are rather low. Amputation, an experimental study with special reference to vascularization

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only partial erection with ongoing cavernous electrical activity was found. Hip and non-vertebral fractures were noted from medical records, written reports or Xray studies. These compensation-based data indicate that there has been a global downward trend in the incidence of OA during the nineties, although the factors that determined this reduced incidence should be further investigated.

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Differential toxicity of protease inhibitors in cultures of cerebellar granule neurons. Serum retinyl esters are not associated with biochemical markers of liver dysfunction in adult participants in the third National Health and Nutrition Examination Survey (NHANES III), 1988--1994. The microbial community in decaying fallen logs varies with critical period in an alpine forest. Also, additives commonly used to ease stresses of encapsulating living cells, such as glycerol, have detrimental impacts on photosynthesis in cyanobacteria.

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Chemistry of 11-vertex rhodathiaboranes: reactions with monodentate phosphines. A comparison of parenteral tenoxicam and diclofenac in the treatment of acute soft tissue injury of the lower limb. Furthermore, febrile responses induced by IL-1 beta, an endogenous pyrogen, and LPS, an exogenous pyrogen, were specifically suppressed in mice lacking the EP3 receptor. Large stationary microstrip arrays for superficial microwave hyperthermia at 433 MHz: SAR analysis and clinical data.

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Strong synergism between GABA(A) and glycine receptors on isolated carp third-order neurons. Atropin produces weakening of the memory on the model of passive avoidance reaction in rats, the effect being more pronounced in evening hours. Psychiatric morbidity following the diagnosis and treatment of early breast cancer. Canine experiments were performed which demonstrated that intra-arterial tolazoline increased distal limb blood flow but did not moderate muscle surface hydrogen ion increase. A vaccination is possible, if the DNA encodes for viral or tumor antigens.

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Treatment must be directed at both the hemorrhage and the underlying tumor. Little is known, however, about the pathogenesis and virulence factors of S.

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Evolution of electronic energy levels in krypton clusters from the atom to the solid. We also give tools to assess embolic risk and to determine the anticoagulant choice for the different presentation forms of atrial fibrillation. In both structures, the conformation of the active site is remarkably similar to the one seen in apo-Sts-2(PGM) suggesting that the spatial arrangement of the catalytic residues does not change during the dephosphorylation reaction. Six months later, a follow-up I(131) whole body scan showed continued radioactive iodine uptake in the retrosternal area and the serum thyroglobulin level remained continuously elevated with levothyroxine suppression therapy (22.3 and 36.4 ng/ml, 6 and 10 months after total thyroidectomy, respectively).

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Action of Pb and alpha-mercapto-propionyl-glycine in vitro, in man We demonstrate the robustness of GSVA in a comparison with current state of the art sample-wise enrichment methods. Response to comment on isolation and identification of compounds from Penthorum chinense Pursh with antioxidant and antihepatocarcinoma properties: bioactivities of pinocembrine group and its derivatives are noteworthy.

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Competition with advanced glycation end product-modified serum albumin at the advanced glycation end product receptor. As predicted, areas with fewer deer had fewer ticks, and fenced exclosures had dramatically fewer ticks in both large-scale forest and small-scale moorland plots. As a mimic for the citrate-based apheresis procedure, our data may enforce the prophylactic application of calcium supplementation to attenuate the short-term elevation of bone resorption related to an acute citrate load.

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Up-regulation of oxytocin receptor messenger ribonucleic acid and protein by estradiol in the cervix of ovariectomized rat. This gene family codes for a group of proteins with in vitro cell adhesion properties and for a group of abundantly expressed pregnancy-specific glycoproteins (PSG) with unknown functions. The association between idiopathic clubfoot and increased internal hip rotation. Consideration on the physical and chemical properties of porcelain and their metallic understructure

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In order to determine the contribution made by damage to fibers en passage associated with electrolytic lesions, Experiment 2 assessed the effects of NMDA-induced lesions in the shell of the nucleus accumbens in the same task. Given the long time since its original description, controversy persists regarding pathogenesis and optimal surgical techniques.

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Volatilisation of ferrocene from ionic liquids: kinetics and mechanism. Spinal MR imaging showed a C2-D3 midline ventrally situated extramedullary tumor with severe spinal cord compression. Moreover, the impact of interaction with NF-25 fibroblasts on HSC-39 cells was investigated using western blot and reverse transcription-polymerase chain reaction.

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Apart from some additional useful effects such as providing multiuser access and reducing influence of narrow-band noise, the method provides significant processing improvement enabling clear separation of multipath arrivals by converting their time delays into their frequency reallocations--the steeper the sweeps, the better the multipath resolution that can be achieved. These results show that repeated audit and standardised follow up can improve the quality of documentation of diabetic follow up, but that this does not necessarily mean that a higher proportion of abnormal results will be detected and acted upon. These proposals accord with recent electrophysiological and functional imaging data, demonstrating posterior parietal involvement in the retention of target locations across saccades. Canadian charitable sector took place in the regulatory and case law areas both federally and provincially. Docetaxel appears to induce an initial enhancement of fluid filtration followed by a capillary protein leakage that leads to edema formation.

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GDPs who had undergone an educational programme in Ni-Ti rotary instrumentation reported they had successfully integrated the technique into daily clinical practice. The main features of direct-to-consumer (DTC) genetic testing suffers from the loss of personal contact between a client and a genetic consultant, who is apt to assess the usefulness of genetic testing and to interpret results of genetic tests and who is also sufficiently trained to provide professional way of consultation. Casuistic ruptures of the rectosigmoid with small intestine evisceration through the anus

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The potential for improvement of the current vaccine and for the development of similar vaccines against other haematophagous parasites is discussed. Results of surgical interventions for malignant tumors in the oro-maxillo-facial region (1947-1960) Electrophoretic and immunological analyses demonstrated that S7 was the only 30S-subunit protein covalently attached to the tRNA.

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Then their recovery status of consciousness and speech was observed. Elevated serum melatonin is associated with the nocturnal worsening of asthma. After a descriptive assessment indicated that coughing occurred while eating, a brief functional analysis suggested that social attention was the maintaining variable.

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Donor-acceptor tubular nanoaggregates of cyclic oligothiophenes. Increased signal intensity areas were present in the lateral corticospinal tract of the brain and cervical spinal cord on a T2-weighted image. These observations suggest that rhTSH more readily displaces endogenous TSH from the mouse than from the rat thyroid TSH receptor, because equal responses were observed when endogenous TSH was suppressed. Studies of midazolam should evaluate the contribution of 1-OHMDZ to the overall PD effect. Our investigation provides valuable insights on the role of social capital with respect to social strategies and community financing mechanisms for the acquisition of modern health care in Africa.

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Preoxygenation with tidal volume and deep breathing techniques: the impact of duration of breathing and fresh gas flow. The other nine patients are alive and well from two to six years after amputation. Formation of cyclic adducts in nucleic acids by the haloethylnitrosoureas. The resulting white bands are challenging for detection and documentation of low activities. S1P is a naturally occurring lipid metabolite, and usually is present at a concentration of a few 100 nanomolar in human sera.

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To describe the characteristics of hepatitis B (HBV) infection in HIV-infected patients and the impact of anti-HBV treatments. Transforming growth factor-beta 1 inhibits L-arginine-derived relaxing factor(s) from smooth muscle cells. Sickle cell disorder, beta-globin gene cluster haplotypes and alpha-thalassemia in neonates and adults from Guadeloupe. Thus, more refined psychometric techniques and multivariate methods of analysis should be utilized to elucidate the etiologic interface of insomnia and psychopathology. Enhanced hypertension prevalence in non-Han Chinese minorities from Xinjiang Province, China.

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Population dynamics of adult Culex mosquitoes (Diptera: Culicidae) along the Kern River, Kern County, California, in 1990. Inflammatory process plays an important role in the pathogenesis of acute coronary syndromes.

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For example, while normal breast has high lumenal expression of CEACAM1, the majority of breast cancers exhibit the early loss of this gene with the concurrent loss of their lumenal phenotype. In the present report we provide evidence that, in murine myoblasts, PGA1 is not able to induce hsp70 expression, whereas it increases the synthesis of the constitutive protein, hsc70, and dramatically induces the synthesis of a 32 kDa protein (p32). However, significant neuroprotection of retinal ganglion cells, the axons of which form the optic nerve, was observed in mice that overexpressed PrP(C). The cosmetic appearance of a removable partial denture is of great importance to both the patient and the dentist.

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Correlation of immunofluorescent and electron micrographs allowed high resolution imaging of microtubule-associated structures that are proposed to be reverse transcription complexes. We performed a retrospective study of 100 patients with FAGA and the same number of patients with MAGA based on the features registered in the personal history of individuals who attended our Trichology Unit (Hospital Universitario Virgen Macarena, Sevilla, Spain) from January 1993 to January 1995. New strategies with dopaminergic drugs: modified formulations of levodopa and novel agonists. Port-site metastasis of extrahepatic bile duct carcinoma after laparoscopic cholecystectomy without evidence of a primary tumour. Twenty-five OCD and 21 healthy participants were recruited via internet.

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In addition, we demonstrate that fluorescently labeled WGA and calcein are taken up by many of the same endocytic vesicles and are incorporated into growing spicules. The major aim of this study was to investigate whether the motivational salience of food cues (as reflected by their attention-grabbing properties) differs between obese and normal-weight subjects in a manner consistent with altered reward system function in obesity. Brassinolide is a plant sterol first isolated from pollen of rape (Brassica napus L.).

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The strong association of biliary dysplasia with cholangiocarcinoma in PSC suggests use of dysplasia as a marker for current or developing malignancy. Often this deformity is a result of trauma involving the bony and cartilaginous vaults, resulting in nasal bone fractures and avulsion of the lateral cartilages into the nasal airway. Cerebral hyperperfusion syndromes caused by a probable failure of vascular autoregulation are rare but potentially serious complications after endarterectomy.

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Uptake characteristics of Cyclosporine A (CsA), an immunosuppressive agent widely used in organ transplantation, have been evaluated in RAJI cells, a human Burkitt lymphoma cell line which (i) does not bear T-cell markers, (ii) is insensitive to CsA after a 1 hr exposure to concentrations up to 50 micrograms/ml, and (iii) does not metabolize CsA. However, the sensitivity, specificity and reliability of the use of the velocimeter in identifying abnormal vascular flow in the vertebral arteries, and therefore its clinical utility, has not yet been fully established. Remodelling of thymocyte nuclei in activated mouse oocytes: an ultrastructural study. Examination of the relationship between obesity and suicidal ideation.

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The release of immunoreactive alpha-melanotropin was not significant in melanoma cells expressing very low levels of melanotropin receptors (IGR3) or in non-melanoma cells (SCC1). The optimal approach to the tumor was determined depending on the findings of intraoperative echocardiography which well visualized the attachment of the tumor.

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This assay showed a very good agreement with INNO-LiPA and p16 findings. Transesophageal echocardiography has a low yield for left atrial spontaneous contrast, left atrial thrombus, or complex aortic atheroma in patients with normal transthoracic echocardiogram and sinus rhythm and in younger patients.

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Basic fibroblast growth factor (bFGF) is a polypeptide growth factor considered to have a role in chemotaxis and mitogenesis of periodontal ligament (PDL) cells. If validated in subsequent larger cohorts, this may be useful in trials of neuroprotective agents.

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A recombinant soluble fragment of the PODXL ectodomain modifies the signaling of the membrane bound PODXL. Endovascular balloon occlusion of the aorta and stent graft repair of the primary aortoduodenal fistula was performed. Voided volume, detrusor overactivity, area under the curve (per minute) and baseline detrusor pressure obtained at natural fill urodynamics were compared to cystometric capacity, detrusor overactivity, leak point pressures and bladder compliance obtained at cystometrogram. The use of new antiepileptic medications in pediatric patients with epilepsy. Pronase treatment enabled adjacent cells to approach each other within 15 nm during dielectrophoresis.

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Approximately 1 x 10(6) cells were separated and injected into the lymph node. Effect of some pharmacological agents on the efficiency of repeated physical performances

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As a result, the images we see accord with what the sources of the stimuli have typically turned out to be, rather than with the physical properties of the relevant objects. Neural stem cells (NSCs) are powerful research tools for the design and discovery of new approaches to neurodegenerative disease.

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Inhibition of NFAT3 activation by shNFAT3 (shNF3) significantly downregulated tumor necrosis factor (TNF)-alpha induction, its receptor TNFR1, caspase 10, caspase 3, and poly (ADP-ribose) polymerase, abrogating DOX-mediated apoptosis in glioma cells. Other often used free flaps include the parascapular and scapular flaps, rectus flap, and gracilis flap.

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Interactions between these two tissues were modeled using a coculture system composed of primary human adipocytes and human skeletal myotubes derived from lean or obese donors. Partially obstructed bladders were compared to bladders in the control and sham treated groups by weight, protein content, and expression of proliferating cellular nuclear antigen, cyclin D3, HsP 70, c-jun and phosphorylated c-jun. Mutants of the WR and Praha viruses with deleted B8R gene were constructed. KATNB1 protein is expressed in germ cells in humans and mouse, mitotic/meiotic spindles and cilia, although the full expression pattern of the Katnb1 gene has not been described.

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Brain injury in the premature infant: overview of clinical aspects, neuropathology, and pathogenesis. Chicken feathers as a natural source of sulphur to develop sustainable protein films with enhanced properties. Tool may help nursing homes avoid risky pneumonia hospitalizations. A novel two-step mechanism for removal of a mitochondrial signal sequence involves the mAAA complex and the putative rhomboid protease Pcp1. Spontaneous renal artery dissection (SRAD) is a rare disease with approximately 200 cases reported in the literature.

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In liver parenchymal cells, interferon gamma increased messenger RNA levels of the transmembrane CD95 isoform and sensitivity of these cells toward CD95-mediated apoptosis. Reliability of arthrometric measurement of shoulder lateral rotation movement in healthy subjects. Following training courses for traditional birth attendants among refugee Afghan women in Pakistan, a survey was conducted to test the knowledge and practices of the participants and of mothers whose babies had been delivered by them, using untrained birth attendants as the basis for comparison. This particular health programme cannot be recommended for implementation.

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To describe site-specific trends in cutaneous melanoma for England as a whole during the last three decades. Experiments with PKC isoform-specific inhibitors and dominant negative isoforms of PKC indicate that PKCdelta is one of key isoforms involved in the FGF2-stimulated Runx2 expression. Autonomic function in narcolepsy: power spectrum analysis of heart rate variability.

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In particular, when an MS imaging study revealed six or more interictal spikes that were densely clustered in a single anatomical location, the MS image was highly correlated with the zone of seizure origin identified by ECoG. Artificial water purification in the Sidi Mohammed Ben Abdellah reservoir dam in Morocco Oral anticoagulation alone is not recommended as a prophylactic treatment strategy.

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Validation of the Depression and Somatic Symptoms Scale by comparison with the Short Form 36 scale among psychiatric outpatients with major depressive disorder. The potential functions include binding of plasminogen, formation of fimbriae, adhesion to collagen, attachment to mucin and intestinal cells as well as induction of immunomodulative response. A c-wave-like cornea-positive potential in the isolated rabbit retina has been described. Knowledge of pharmacy students about doping, and the need for doping education: a questionnaire survey.

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A majority of progression studies are based on cross-sectional single point data or short-term clinical observations. False positive seroreactivity to Borrelia burgdorferi in systemic lupus erythematosus: the value of immunoblot analysis.