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In the joints of these mice, we found elevated levels of cells of the monocyte/macrophage and granulocyte lineages and of polymorphonuclear neutrophils (PMNs), most of which expressed Gr-1, indicating that they were mature, tissue-degrading PMNS: Cultured synoviocytes and PMNs from these animals overexpress GM-CSF, suggesting that the hematopoietic changes induced by IL-1 and the consequent PMN activation and joint destruction are mediated by this cytokine. Quantitative increases in surgical house officer clinical activity as the basis for increased work loads in a university hospital. Effect of iron as a new type of phosphate binder in hemodialysis patients.

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Female CD-1 mice were exposed to UVA (19 J/cm2) and total RNA was isolated from the skin. Vasculogenic female sexual dysfunction: the hemodynamic basis for vaginal engorgement insufficiency and clitoral erectile insufficiency. Continued propagation of these misconceptions in some cases may significantly impede the advancement of MSC-based therapies in clinical medicine.

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However, whole-body FDG hybrid PET is currently inadequate as a single modality for staging NHL and is complementary to CT. Percutaneous cooled-tip microwave ablation under ultrasound guidance for primary liver cancer: analysis of major complications in 693 patients

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Expression of heparin-binding epidermal growth factor-like growth factor in patients with gastric carcinoma The mean values of this bony process of the clavicle adjacent to the articular disc were 2.1, 4.7, and 6.0 mm, respectively, in the three types of articular disc. The platelet granule protein (TS) is extracellularly secreted upon platelet activation and then binds to the platelet surface where it can interact with various adhesive proteins.

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Modulation of delta 6 and delta 5 rat liver microsomal desaturase activities by dexamethasone-induced factor. The biological activity of selected compounds identified from this screen revealed low micromolar antiviral potency against dengue virus for two of the compounds.

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Alternative technique for endovascular treatment of an abdominal aortic aneurysm with a severely angulated neck. New antiinflammatory compounds that inhibit tumor necrosis factor production: probable interaction with protein kinase C activation.

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TERRA (TElomeric Repeat containing RNA) is a long non-coding transcript that stems from sub-telomeric regions and continues into the telomeric tract and is therefore a hybrid of both sub-telomeric and telomeric sequence. They also provide tremendous promise for regenerative medicine because of their capacity to proliferate and differentiate into a variety of mature cell types. We hypothesised that thorough testing of the relationships between IRF5 polymorphisms, expression data from multiple experiments and SLE-associated haplotypes might provide useful new information. These data indicated the possibility of penetration of titanium dioxide nanoparticles through the gastrointestinal barrier under near-physiological conditions.

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In another case, the band, after being cut, was locked in the gastric wall and required laparotomic removal. Surveillance data collected from East Baton Rouge Parish in 2002 were examined to establish baseline data on WNV activity, to support the current design of disease surveillance programs, and to target vector control efforts in the parish. These results provide evidence that in addition to their immunomodulatory effects, thalidomide, lenalidomide and pomalidomide can impair the metastatic capacity of tumours, and that this mechanism may involve alterations to cell signalling functionality. Anti-MET targeted therapy has come of age: the first durable complete response with MetMAb in metastatic gastric cancer. In the in vitro antibacterial activity test, CIP-microspheres showed lower antibacterial activity compared to free CIP because of their sustained-release properties, while empty microspheres did not affect the growth of microorganisms.

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Retinoid-related orphan receptors (RORs): roles in cell survival, differentiation and disease. In addition, these cells displayed a decreased sensitivity to cancer chemotherapeutic, bifunctional, DNA-damaging agents such as cisplatin, melphalan, and mechlorethamine, resulting in enhanced mutagenesis compared with control cells. Although he received various treatments, such as high-dose immunoglobulin therapy, prednisolone, and splenectomy, they were ineffective. Long-term preservation of rat skin tissue by epigallocatechin-3-o-gallate.

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This advantage enables precise distance and shape measurements of fast rotating surfaces. The core embryonic stem cell transcription factors Oct4, Sox2, and Nanog are expressed in germ cell tumors (GCTs) and have been proposed to play a regulatory role in tumorigenesis. On the other hand, SCID mouse cells (SC3VA2) exposed to wortmannin exhibited significant increases in radiosensitivity, possibly because of some residual function of DNA-PKcs.

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Evidence collection was performed based on 9 questions regarding the diagnosis of fibromyalgia, structured using the Patient, Intervention or Indicator, Comparison and Outcome (P.I.C.O.), with searches in the main, primary databases of scientific information. Significance of hyperintense vessels on FLAIR MRI in acute stroke. Epigenetics and early life origins of chronic noncommunicable diseases.

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Premature labour with renal infections: the action of coliform endotoxin on the pregnant rat uterus. This method has been applied to the total syntheses of two isoindolobenzazepine alkaloids, lennoxamine and chilenine. This study was done to develop an accessible multimedia program about breast self-examination on the Internet. Investigation of sphingosine kinase 1 in interferon responses during dengue virus infection. We compared 34 type 2 diabetic patients with non-diabetic subjects as regards serum total Mg.

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Activity of disulfiram (bis(diethylthiocarbamoyl)disulphide) and ditiocarb (diethyldithiocarbamate) against metronidazole-sensitive and -resistant Trichomonas vaginalis and Tritrichomonas foetus. New production methods for NCA Pt, Ir, Au, Cu and Ga radiotracers are presented, with some details on radiochemistry and quality controls. A retrospective time-series analysis of weather station observations and ICD-coded HRI ED visits to ten hospitals in south eastern Ontario, Canada, was performed from April 2003 to December 2008 using hospital data from the National Ambulatory Care Reporting System (NACRS) database, ED patient chief complaint data collected by a syndromic surveillance system, and weather data from Environment Canada.

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Efficient neoosteogenesis was observed in animals treated with LMP-3-expressing cells (group 1) as soon as 4 weeks after surgery. The authors offer a brief description of behavioral activation therapy and examine how to adapt this therapy for use in patients with medication-responsive chronic depression.

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This systematic review will identify the extent of the current research on smoking and alcohol cessation interventions in patients with head and neck cancer and oral epithelial dysplasia. Upon further development, the PASE initiates a process that resembles posterior primitive streak development in a SNAI1-dependent manner. Antibody-mediated rejection--an ounce of prevention is worth a pound of cure. While the effect of flow in the section-select direction is identical to that in a standard two-dimensional Fourier transform (2DFT) acquisition, flow in the phase- or frequency-encoding directions can have substantial effects on the image, different from that in 2DFT imaging. When the two interstitial Sc atoms get close to each other, the infrared response decreases and shifts to short wavelengths.

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These results confirm the complex role played by this peptide in the regulation of zona glomerulosa cell physiology. p53 and RB gene is emphasized as a key gene in induction of cell cycle progression and apoptosis. Melatonin protects against oxidative stress induced by the kidney carcinogen KBrO(3). Otitis media: focus on antimicrobial resistance and new treatment options.

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Prevalence and management of invalid GeneXpert enterovirus results obtained with cerebrospinal fluid samples: a 2-year study. In this article new pathophysiological theories of portal hypertension are reviewed. Protection against retrovirus pathogenesis by SR protein inhibitors. Ochratoxin A in wheat: certification of two reference materials. It is assumed that it was this quality in the therapeutic relationship that led to the formation and development of psychic structure.

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These projections of future financial costs may be used as a starting point for mobilizing global resources. The Meyer-Probst questionnaire on typical encephalopathic behavior in children with early brain damage was used with 32 children attending special schools, at intervals during the first four years of school. Higher levels of endogenous bioavailable testosterone contribute to atrial fibrillation development in men. Mycoplasma bovis was also demonstrated at sites of mild mononuclear cell infiltration in the livers and kidneys of 2 calves.

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The Ras/Raf-MAPK, G12/13-Rho-RhoA and PI3K-AKT/PKB signal pathways may be involved. Two-photon photoemission as a probe of electron interactions with atomically thin dielectric films on metal surfaces. The cardiovascular safety of cyclooxygenase-2 (COX-2) inhibitors The evidence concerning the determinants influencing self-efficacy and the self-efficacy interventions makes clear how nurses can develop and tailor self-efficacy interventions for the clinical practice of people with stroke. High density lipoprotein (HDL) allows the release of free cholesterol from the plasmatic membrane inducing the regression of atherosclerotic lesions.

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No sensitization was observed after repeated morphine treatment (3.0 mg/kg, s.c., every other day for 9 days) when morphine injections were preceded by 0.3, 1.0, or 3.0 mg/kg LY293558, whereas significant sensitization was observed when morphine injections were preceded by vehicle or 0.1 mg/kg of the antagonist. Chronic physical illness did not have an independent effect on the GHQ score. In this study we evaluated a novel approach to guide the bone marrow-driven articular cartilage repair response in skeletally aged rabbits. Two thirds of left hemiparetic and one third of right hemiparetic patients had deficits in limb position sense.

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Low serum dopamine-beta-hydroxylase activity in the dysequilibrium syndrome. This article is part of a Special Issue entitled Regulation of Cellular Processes by S-nitrosylation. New Bactrodesmiastrum and Bactrodesmium from decaying wood in Spain. Small bowel perforation in a hernia sac after TVT placement at the time of colpocleisis.

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The most severely affected of the four sisters was successfully treated with propranolol hydrochloride prophylaxis. At the same time the disturbance of the reflectory reaction of the brain vessels in the course of forming the vasomotor reflexes and the absence of significant changes in response to GABA were noticed.

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The two chymotryptic fragments are thought to contain respectively five and two transmembrane alpha-helices in native BR. The accuracy and sensitivity of the 99Tcm-phosphate bone scan and conventional skeletal radiology have been compared in 372 patients with documented malignant disease and 75 control subjects. Morphological changes in anaplastic gliomas treated with radiation and chemotherapy.

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Lack of physiological BP decrease during the night seems to be connected with higher BMI and triglycerides and with lower HDL cholesterol. A case report and review of the exaggerated lithotomy position, in particular, and other position-related rhabdomyolysis is presented. Plasma and erythrocyte magnesium concentration in the postoperative period.

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A targeting device that is not completely radiolucent can make precise positioning of these screws in the lateral plane difficult. In vitro functional studies of the mutant TSHRs were also performed. Using Lineweaver-Burk analysis of binding equilibrium data, the dissociation constant of CsA for this binding site was approximately 2.2 microM. A 30 cm elevation produced significant drug delivery boluses - up to seven times the programmed rate at 2mL/h.

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In general it is assumed that the change in the streaming potential is proportional to the degree of heterogeneity. It was concluded from this study that cell proliferation (as measured by the Ki-67 antigen) at the ITF had a strong positive relationship with histological grading in human oral SCC.

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Cationized ferritin (CF), pI approximately 8.4, which binds to cell surface acidic sites via an electrostatic noncovalent interaction, was rapidly internalized by the oxidized endothelium in coated structures and in vacuoles. The aim of this study was to determine by ciliary beat frequency (CBF) analysis whether monosaccharides or peptides mimicking glycostructures represent blockers of PA lectin binding to human airway cilia. Smoking did not seem to influence the relationship between asthma and body mass index.

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Express admit units (EAUs) have been proposed as a way to expedite patient flow through the Emergency Department (ED). This paper describes a conceptual framework for the development and evaluation of stress-prevention programs for military personnel. Targeting EGFR is an effective approach to treat EGFR-positive HNSCC. Iodoacetate-induced inhibition and enhancement of spontaneous leukemia in AKR mice.

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We previously identified a region of recurrent amplification on chromosome 22q11.21 in a subset of primary lung adenocarcinomas. The key to diagnosing and managing a ureteric injury is to have a low threshold for suspecting its presence. In this chapter, we discuss the recent advances made in our understanding of the shape of the eukaryotic transcriptome. Wound healing and complications of the liver after percutaneous transhepatic cholangiography. Spatiotemporal and kinematic effect of peroneal nerve stimulation versus an ankle-foot orthosis in patients with multiple sclerosis: a case series.

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This fact and several archeological findings provide evidence that the archetypal domestic chicken was of the light egg type. The opposite situation, retraction of the membranes is, however, only incidentally described and relatively little attention has been paid to its significance. Growth of the cranial bones in human fetuses (2nd and 3rd trimesters). Together these developments may lead to new therapeutic strategies.

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The geometrical details of the solvent structure in vitamin B12 coenzyme crystals with respect to hydrogen bonding and nonbonded contacts, are described. On the changes of the corneal epithelial cells after frozen storage