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The transcripts of witchcraft trials held before the Inquisition reveal the complexities of early modern conceptions of natural and supernatural. Phospholipase A(2) (PLA(2)) is important hydrolytic enzyme involved in the regulation of specific types of messengers, with significant roles in the innate immune response. The exposure of MCF-7 cells to conventional form of doxorubicin resulted in the decrease of p53 expression and the increase of Bcl-2 expression. Concentrations of ampicillin and the methoxymethyl ester of hetacillin were measured in plasma, prostatic fluid, and spinal fluid of dogs receiving ampicillin or the hetacillin ester by continuous intravenous infusion. After the initial demonstration that a reduced VWF survival is present in patients with R1205H mutation (VWD Vicenza), several other mutations, mostly occurring in the VWF D3 domain, have been shown to be associated with accelerated removal of released VWF.

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These results indicate that exogenous sulphatide is targeted to the Golgi apparatus prior to its lysosomal degradation. Dietary habits were evaluated through a semi-quantitative Food Frequency Questionnaire (FFQ), whereas adherence to the Mediterranean diet was assessed by a diet score. Immunological and model peptide studies on the processing of immature astacin, a zinc-endopeptidase from the crayfish Astacus astacus.

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No adverse effects like allergic reactions, tachyarrhythmia or thrombembolic events occurred in any of the patients. Here, we investigated the role of DARPP-32 in promoting resistance to treatment with TRAIL. Modulation of the activity of central serotoninergic neurons by novel serotonin1A receptor agonists and antagonists: a comparison to adrenergic and dopaminergic neurons in rats. Requirement of CPR has a detrimental effect on RAAA-patient outcome. Both the patients had certain biochemical and hepatic histologic features in common.

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Each HSC aliquot with or without MSCs was autologously injected into the bone marrow (BM) cavity of right or left side, enabling the comparison of in vivo fates of the two HSC grafts in the same body. The vaccine had consisted of liposomes that contained both the recombinant protein antigen and also contained monophosphoryl lipid A (MPLA) as an adjuvant. RAD51-independent break-induced replication to repair a broken chromosome depends on a distant enhancer site. Some children with idiopathic short stature may have partial insensitivity to GH due to mutations in the GH-receptor gene. Arrhythmic sudden cardiac death in a 3-year-old child with intimal fibroplasia of coronary arteries, aorta, and its branches.

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Among constituents of the sphingolipid fraction, PHS and DHS show striking inhibition in a non-competitive manner. Samples of collagen were cross-linked by two different methods: (a) glutaraldehyde and (b) a combination of dehydrothermal treatment and cyanamide. Phase II trial of carboplatin and paclitaxel in non-small cell lung cancer patients previously treated with chemotherapy. Two patients with a small lacune and a hemorrhage in the pontine tegmentum showed a selective sensory deficit of the medial lemniscal type.

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The nature of Ru-NO bonds in ruthenium tetraazamacrocycle nitrosyl complexes--a computational study. Cerebral hemiatrophy: classification on the basis of MR imaging findings of mesial temporal sclerosis and childhood febrile seizures. The biosynthesis of benzoic acid glucosinolate esters in Arabidopsis thaliana. Biomechanical assessment and 3D finite element analysis of the treatment of tibial fractures using minimally invasive percutaneous plates.

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Filter paper blood lead test was carried out monthly using the filter paper blood lead proficiency testing program of Centers for Disease Control in the United States. The main objective is to offer a low cost virtual reality system to boost current adopted training methodologies for bone marrow harvesting. During the first 6 months after bariatric surgery, sE-selectin levels decreased. Synthesis and biological activity of novel mycophenolic acid conjugates containing nitro-acridine/acridone derivatives.

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This article outlines how the tobacco industry has undermined tobacco control efforts in Lebanon since the early 1970s. Binding of the EcoRII methyltransferase to 5-fluorocytosine-containing DNA. It is an active material obtained by connecting heme with a different-length peptide section after physical and chemical processing. Intrathecal fentanyl added to hyperbaric ropivacaine for cesarean delivery.

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A total of 91 breast abnormalities, 70 benign and 21 malignant, were evaluated. Integrative studies have stressed the role of aquaporins in maintaining the whole plant water and nutrient status. Restrictive provisions in these laws should be reformed, and their protective norms effectively implemented including by translating them into national policies and ensuring sensitization and training of healthcare workers and communities. In particular, antibodies to different cytokeratins and to transthyretin revealed considerable and constant differences of immunoreactivity.

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To gain insight into FAEA hydrolysis activity, we solved its crystal structure. Computed tomography and cystoscopy showed a mass in the distal region of the right ureteral stump. When tested drug-free, yohimbine-treated rats showed equivalent levels of freezing and suppression to controls.

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This doubles the number of restriction endonuclease structures now known from two to four, and enables a comparative analysis of their structures and modes of DNA recognition. Furthermore, antitumor efficacy may no longer correlate with normal hematological or nonhematological toxicity, and it may be more appropriate in phase I trials to identify the maximum target inhibition dose rather than the maximum tolerated dose. Decreased pH increases extracellular adenosine in CNS regions as diverse as hippocampus and ventral medulla. For single-component metal solutions, the metal removal capacities of the beads for Pb, Cd, Ni and Zn were 4.06, 3.76, 0.36 and 1.36 mg/g, respectively.

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The consequences of this increased stress on the immune system are unclear. Determination of ethyl biscoumacetate and its metabolite 7-hydroxyethyl biscoumacetate in human serum by high-performance liquid chromatography and mass spectrometry. Previously, the application of a continuous time hidden Markov model with discrete states was used to model geriatric inpatient behaviour. The dynamic nature of biological invasions necessitates a more quantitative understanding of how postintroduction changes in invader traits affect invasion processes.

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Deep buccal cavities in 16 human pairs of premolars, 32 teeth, were restored in vivo with a light cured composite resin, P-50. Recombinant LV particles contain viral proteins necessary for their packaging, infectious and integrating functions.

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We found key interactions between the inhibitors and the hPIV HN glycoprotein and identified important factors for the inhibitory activity. The results of this meta-analysis suggest that physical activity is associated with a larger breast cancer risk reduction among women who are normal weight or overweight than among women who are obese. The problem is reduced to finding a polynomial which is close to 1 in a disk and close to 0 in another disk, and such a polynomial is constructed. The treatment of 3,5-dibenzoylporphyrins with ammonium acetate provided novel oxopyridochlorins as the first examples of pyridine-fused porphyrinoids, which displayed absorption bands reaching into the near IR region and an ability to sensitize singlet oxygen effectively. Thus, the ability to transfer gene expression to normal, resting PBMC could complement gene transfer strategies that target dividing precursor cells.

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Over one dosing interval, drug concentrations, clinical data, and genotype for Cytochrome P450 (CYP)3A5 polymorphisms were obtained. Extending the spectra adds another CD band to the data and increases the information content from the equivalent of five to six.

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Repeated chelation therapies can, over a four-year period, slow progression of renal insufficiency in non-DM patients with high-normal BLB. We present here the construction of a new recipient strain that lacks the TRP1 region and that allows a high efficiency of gene deletion.

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In the most severe cases, NAIT may result in intracranial hemorrhage and may lead to death or neurologic sequelae. Child abuse and pediatric social illness: an epidemiological analysis and ecological reformulation. Use of proscar in preoperative preparation of patients with benign prostatic hyperplasia before transureteral resection Patients with biliary acute pancreatitis (AP) and clinically acute cholecystitis and/or cholangitis benefit from antibiotic treatment.

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Through an international rescue operation, the dead bodies of 27 were found and the remaining 26 crew are still missing. Transcriptional and epigenetic functions of histone variant H2A.Z. Studies on the pathogenesis for the occurrence of postoperative bronchial fistula

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Medium-term and long-term results of organ survival improved less markedly. Such a rapid rise can therefore not be explained by a change in genotype, but must result from environmental factors and their interaction with our genes. Buprenorphine is a common analgesic in experimental research, due to effectiveness and having few side-effects, including a limited influence in the immune and endocrine systems. In stress incontinence, CCU was of greater value for the preoperative planning of operative technique, vaginal or abdominal, but could be omitted when pelvic examination did not disclose genital prolapse, as this excluded posterior suspension defects at CCU. Logical Differential Prediction Bayes Net (LDP-BN), that calculates the risk of breast disease based on mammography findings.

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Asymmetric cortical degenerative syndromes: clinical and radiologic correlations. We also analyzed the benefits of using an instrument with a faster scan rate, the new TripleTOF 5600 mass spectrometer. Thirty four AgP patients and 29 healthy controls were included in this study. A cluster of RNA editing sites observed outside the cox3 coding region identifies a novel reading frame orf95 in higher plants with significant similarity to a subunit of respiratory chain complex II. The aim of the present study was to describe the collision-induced dissociation behavior of the four most common aflatoxins: B1, B2, G1 and G2.

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Upregulated expression was found in IL-15 since the first day after transplantation and in IL-7 and IL-13 since day 6. The primary outcomes were related to PONV and postanesthesia care unit (PACU) discharge time, whereas secondary outcomes were related to early postoperative pain. Because of the intermingling of some Aveneae and Seslerieae lineages in Poeae and vice versa, we propose to expand Poeae to include all the aforementioned lineages. First experiences with ECS show good sensitivity rates even by blinded assessment for esophageal and colonic lesions.

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Using MRI, we show that human central nervous system stem cells transplanted either to the neonatal, the adult, or the injured rodent brain respond to cues characteristic for the ambient microenvironment resulting in distinct migration patterns. Paula had foreseen her death at a young age and was apprehensive about her pregnancy, yet she painted herself as pregnant in her best known self-portrait, thus underlining the importance of the pregnancy in her life.

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We demonstrate for the first time that BCL-xL and BCL2 delayed serum-induced and Myc-induced, but not E2F-induced, cell cycle entry. Towed neurites showed a high rate of spontaneous growth cone advance and could continue to grow out for 1-3 d after towing.

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Trabectedin-related rhabdomyolysis: an uncommon but fatal toxicity. The evaluation of the LH/FSH ratio between the peak values of the two gonadotropins after a GnRH 100 micrograms iv bolus, may be useful in the diagnosis of PCOS in those patients who present an LH/FSH less than 1 in basal conditions even in the presence of clinical and ecographic aspects of PCOS. In light of recent guideline changes for resuscitation, there is a need to identify the efficacy of bag ventilation by prehospital care providers. Excessive buckling of the only nonreinforced catheter was initially overcome early in the pathway in a staccato, stepwise fashion. The structural aspects of the pharmacological activity of calcium antagonists.

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We performed a cohort analysis of consecutive patients at a university-based medical center from April 1997 through October 1999. Afterwards, free dental treatments, including extractions, scaling and fillings, were offered to the subjects every year according to their needs. We report the in vivo observation of protein diffusivity in rabbit lenses with the use of laser light-scattering spectroscopy.

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I is able to metabolize the polycyclic aromatic hydrocarbon (PAH) fluoranthene and to provide an initial characterization of the metabolites produced. Using stable isotope dilution LC/ESI/MS/MS, we show that while guanine is the preferred purine targeted for bromination as a free nucleobase, 8-bromoadenine is the major purine oxidation product generated following exposure of double-stranded DNA to either HOBr or the EPO/H(2)O(2)/Br(-) system. In addition, regimens employing gemcitabine with oxaliplatin and/or fluoropyrimidines have shown promising results and warrant additional investigation in cholangiocarcinoma.

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The epidemiology is complex and includes both environmental and host factors. Chronic intermittent hypoxia induces atherosclerosis via activation of adipose angiopoietin-like 4. In conscious, sedated children with myocardial hypertrophy, systolic function assessed by an index of force generation remains unchanged. This discussion is preceded by a general introduction to VSFS studies at aqueous surfaces and a description of the fundamental principles underlying the technique. Comparable ages for the independent origins of electrogenesis in African and South American weakly electric fishes.

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The pathogenic properties of a novel and conserved gene product, KerV, in proteobacteria. This work provides straightforward and efficient approaches to the synthesis of multifunctionalized 2,3-allenols and stereodefined alkenes from the same starting material of propargyl epoxides. Exacerbated postprandial lipid responses are associated with an increased cardiovascular risk. The paradigm of stereotactic body radiotherapy (SBRT) has dramatically different dosing schemes but, to date, there has still been no comprehensive set of SBRT normal organ dose tolerance limits. The ratings were then compiled and processed using ROC and variance analysis.

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Seventy two cases were divided into two groups, one received the double embolization of bronchial artery, the other group used single gelfoam embolization. Accreditation performance areas were reduced into subscores to represent patient safety practices. We began an experimental and genetic analysis of the microevolution of P8.p function.

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Many CLs are detectable using 7T MRI in patients with pediatric-onset MS despite relatively brief disease duration, absence of progressive disease, and very limited physical disability-supporting early cortical involvement in MS. Our understanding of the molecular pathology of lung cancer is advancing rapidly with several specific genes and chromosomal regions being identified. Patients with all forms of angina, stable effort and unstable rest angina, and those with coronary artery spasm have very frequent episodes of silent myocardial ischemia during ordinary activity.

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Backbone 1H, 13C and 15N assignments of a 59 kDa Salmonella typhimurium periplasmic oligopeptide binding protein, OppA. However, after their removal, we observed that BRM expression remained elevated for several days, and during this period, BRM activity was detected.

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Slowing of event-related potentials in primary progressive aphasia. The extensive spreading-type SCC of the esophagus, which was considered to result from the widespread or multiple carcinomatous changes of the esophageal epithelium, was found to not be as rare as generally thought. However, there are concerns that the benefits associated with distribution of nanoparticles may also be accompanied with risks to the environment and health.

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In comparison with bupivacaine, ropivacaine produced a shorter duration sensory block (median at 68, 90 and 120 min in groups 2, 3 and 4, respectively, vs. Each T- and B-lymphocyte carries unique rearranged TCR or immunoglobulin gene, which has been applied to detect clonal from non-clonal T- and B-cell proliferation.

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Our study is the first to identify the tumor-suppressive role of miR-22 and its associated signaling in the p53-mutated colon cancer cells and highlighted the chemosensitive role of miR-22. The relationships of the bile acids to intestinal bacteria and their recurrent exposure in the enterohepatic circulation are discussed. Directional rearrangement of the actin cytoskeleton within the neutrophil, along with modulation of integrin-mediated adhesion, are necessary for neutrophil migration. Importance of monitoring renal function in patients with cancer.

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Because the total score was related to outcome, the instrument may have use in screening patients with acute or subacute spinal pain in clinical situations. Total gastrectomy and secondary plasty with an ileocolonic graft All the fractures were evaluated both clinically and radiologically for the healing. The findings suggest that contrast MG with nonionic water-soluble agents is a rather effective technique in the diagnosis of PHLID. A high volume in thoracic surgery practice and a single thoracic surgeon can make a difference in the outcome with the concept of fast-track surgery either via video-assisted thoracic surgery or open thoracotomy.

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Various clinical settings of AKI, including patients after cardiac surgery, pediatric patients, and critically ill patients. HPLC fingerprint chromatogram analysis of some Taraxacum in Henan province

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The RWV bioreactor represents an additional new technology for culturing prostate tissue for further investigations concerning the basic physiology and pathobiology of this clinically important tissue. It is expected for us to promote resuscitation science even in traditional theoretical field but also in the field of education, implementation, and team approach. Neonatal stroke occurs in 1 in 2300-5000 live births, the incidence of which is lower than that in adults, but still higher than that in childhood.

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The mean silver binding nucleolar organizer region (Ag-NOR) value in adenoma was 4.29, and in carcinoma 7.16 (P less than 0.001). These findings suggest the hepatoprotective and antioxidant effects of CA leaf extract, which offered protection against ethanol-induced toxicity.

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In order to study the relationship between the basement immunological changes, TCM Syndrome Differentiation and prognosis, alkaline phosphates antialkaline phosphatase (APAAP) and ELISA assay were used to determine the T lymphocyte subsets, the platelet associated antibody (PAIgG, PAIgA, PAIgM) and plasma antiplatelet-autoantibodies (GP II b, GP III a, GP I b) in 55 chronic idiopathic thrombocytopenic purpura (ITP) and 53 healthy subjects as control. Pax-3 and Pax-7 label muscle progenitor cells during myotomal myogenesis in Coregonus lavaretus (Teleostei: Coregonidae). The optimal models of density, modulus of rupture and tensile strength parallel to grain were obtained through BiPLS method that separated the whole spectra pretreated by standard normalized variate, second derivative and first derivative respectively into 20, 30 and 20 intervals.