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The data from the wedge experiments suggest that the repolarization time of the longest M cell action potential determines the Q-Tend interval, while that of the epicardial action potential determines the Q-Tpeak interval. Validation of the classification of hypovolaemic shock suggested by the prehospital trauma life support (PHTLS) in its sixth student course manual. Inflammatory active skin nodules show a necrotizing arteritis with variable amounts of fibrinoid necrosis and leukocytoclasia, edema and inflammatory cells. The CA was then specifically captured on anti-CA-immobilized magnetic beads, which were packed between two detection windows in the capillary column, during the electrophoresis. Mediastinal cystic necrosis of the aorta and dissecting aneurysm with rupture into the pericardial sac.

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The clearance rate and reabsorption rate of calcium were also significantly lower in the affected cattle, but the excretion rate and reabsorption rate:clearance of calcium were not different between the normal cattle and the cattle homozygous for the condition. Old age cognitive status was measured by using a validated telephone interview.

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Though there are few reports of such a high serum CA19-9 level, the possibility of benign biliary tract disease should be considered in patients showing an extraordinarily high serum CA19-9 value. There is no evidence that the liberalized abortion legislation has led to the use of induced abortion as a method of birth control.

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Prevention of acute rejection and allograft vasculopathy by everolimus in cardiac transplants recipients: a 24-month analysis. Sulforaphane induces apoptosis in human hepatic cancer cells through inhibition of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase4, mediated by hypoxia inducible factor-1-dependent pathway. Differential cross sections for coherent and incoherent neutral-pion photoproduction from calcium. Phase separation in fluids exposed to spatially periodic external fields. Energy-dependent photodissociation dynamics probed by fluorescence polarization.

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To apply and validate an adapted version of an existing adult patient questionnaire in a study of parental satisfaction with paediatric care in a university hospital. Deletion analysis of this region showed that at least two physically separated sequence elements are involved, a distal one starting between -443 and -395 and a proximal one starting between -177 and -118, and suggested that these sequences interact with positively acting transcriptional factors in muscle cells. No functional link seems to exist with the highly conserved GTPase Cdc42 involved in cytoskeletal polarization and cell polarity. We evaluated patient and tumor characteristics that might predict prolonged warm ischemia time.

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Pure cell lysate as well as that of soil DNA was used as template in MDA reaction. Toxicity assays based on bioluminescent bacteria have several advantages including a quick response and an easily measured signal. The submucosal glandular or cystic elements were connected with the overlying gastric mucosa through a defect of the muscularis mucosa, suggesting that this polyp may have been formed by the heterotopic inverted downgrowth of mucous glands into the submucosa. Inducible nitric oxide synthase expression in gastroduodenal diseases infected with Helicobacter pylori. Interleukin (IL)-17 (also known as IL-17A), the signature cytokine of the newly described T helper 17 (Th17) cell population, has been implicated in the pathogenesis of numerous autoimmune diseases including rheumatoid arthritis.

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Although the progression of rotator cuff tears seems to play a role in the development of cuff tear arthropathy, information is lacking regarding the natural progression of rotator cuff tears to cuff tear arthropathy. The biological activities of LNP-siRNA, including the cellular uptake, CDK4 expression and G(1) cell cycle arrest, in both HeLa cervical cancer and MDA-MB-468 breast cancer cells were evaluated by flow cytometry, confocal microscopy, quantitative reverse transcription PCR (qRT-PCR) and Western blotting, respectively. Dehydroepiandrosterone stimulates neurogenesis in mouse embryonal carcinoma cell- and human embryonic stem cell-derived neural progenitors and induces dopaminergic neurons. Epigallocatechin Gallate as an anti-obesity therapeutic compound: an in silico approach for structure-based drug designing.

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Autopsy revealed immature plasma cell infiltration in multiple organs including the heart, liver, spleen, kidneys, intestine, bone and bone marrow. Capsule enteroscopy is a cost-saving approach in the evaluation of patients with obscure gastrointestinal bleeding. Chondroitinase treatment following spinal contusion injury increases migration of oligodendrocyte progenitor cells. The post-treatment admission rate, both immediate and delayed, was 14.2 per cent.

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The use of long term hormone replacement therapy has mixed risks and benefits that requires individual patient counselling. Loss of proliferation and differentiation capacity of aged human periodontal ligament stem cells and rejuvenation by exposure to the young extrinsic environment. A pilot study without hematopoietic growth factor support evaluating toxicity and response. Moreover, PCR products from 8 obligate heterozygous females (carriers) consisted of two different fragments with enlarged and normal size. To evaluate a strategy for successful laparoscopic-assisted vaginal hysterectomy (LAVH) in patients with extensive pelvic adhesion.

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Measurements were obtained with high-resolution videography, with the eyes in primary position, in 45-degree right gaze, and in 45-degree left gaze. We then discuss the accuracy of these measurements using a 64-slice spiral CT. Using a 10-fold cross-validation approach, we were able to achieve a sensitivity and specificity of 0.82 and 0.71, respectively, and we show that this performance is strongly influenced by the distance to the transcription start site.

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Such frequencies are similar to the discharge frequencies recorded during seizure initiation in some patients with epilepsy. In the present report the use of HLA-DR as a representative of the Major Histocompatibility Complex class II genes in the allocation of organs is discussed. These diagnostic methods could be useful in the early diagnosis of CNS aspergillosis. The long-lasting multidisciplinary program was superior to the exercise program in reducing disability, fear-avoidance beliefs and pain, and enhancing the quality of life of patients with chronic low back pain. hy.926 obtained by fusion of HUVEC cells with the epithelial cell line A 459 was irradiated with 0-5 Gy.

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In female mice, A-myb is expressed in breast ductal epithelium, mainly during pregnancy-induced ductal branching and alveolar development. Lumbar spine fusion for chronic low back pain due to degenerative disc disease: a systematic review.

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The anatomy of the superior gluteal neurovasculature (SG NV bundle) is well described as running along the posterior ilium, providing innervation and perfusion to important abductor muscles. After 2 years of experience with 2,868 endoscopic manipulations and varying dosage schedules in 59 dogs, safe effective techniques for recurrently delivering carcinogens and sequential biopsies of the same sites have evolved.

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Moreover, patients with ALD did not show the peripheral expansion of CD4/CD8 double-negative T cells that characterizes the ALPS phenotype. Have we drawn the wrong conclusions about the value of care pathways? Fast synaptic transmission mediated by alpha-bungarotoxin-sensitive nicotinic acetylcholine receptors in lamina X neurones of neonatal rat spinal cord. What are the critical cellular and molecular players at the primary tumor site where metastatic cascade initiates?

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Effects of dietary fat on appetite and energy intake in health and obesity--oral and gastrointestinal sensory contributions. The two major applications of whole post-implantation rat embryo culture (WEC) are as a test for teratogenicity in safety evaluation studies and as a tool in the investigation of mechanisms of teratogenesis.

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Relevance of drug-induced extrapyramidal reactions to behavioral changes during neuroleptic treatment. Cortical gamma generators suggest abnormal auditory circuitry in early-onset psychosis. Professor Wincenty TOMASZEWICZ, a profile of a scientist and social worker

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However, shifted lesioned rats displayed a more persistent increase in latencies than shifted unlesioned rats, exhibiting significantly longer latencies than those of unlesioned rats by Day 15. The aims of reconstruction are the preservation of renal function and achievement of urinary continence. Bilateral lower limb compartment syndrome: a potentially destructive complication of breast reduction.

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For both males and females, disorder at age 15 was strongly predicted by histories of early mental health problems. Early ICI and intracortical facilitation (ICF) and late ICI were evaluated by paired TMS. Cluster-randomised trials were eligible for inclusion but none were identified.Cross-over study designs were unlikely to be relevant for this intervention, and we planned to exclude them if any were identified. The epithelial sodium channel (ENaC) modulates sodium reabsorption in the kidney, but little is known about sex-specific regulation of ENaC subunit expression.

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Measurement of the neutrino mass splitting and flavor mixing by MINOS. Study of the acute cardiovascular effects of several antihypertensive agents with the measurement of plasma catecholamines in mice. Bacteriologic, histologic and ultrasonographic findings in strictures recurring after urethrotomy.

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But when morphine is used in large doses, especially in renal patients, an active metabolite of morphine, morphine-6-glucoronide, may cause delirium and myoclonus and sometimes antagonize the analgesic effect of morphine. The objective of this study was to estimate the influenza VE against medically attended influenza using a test-negative case-control design with rapid influenza diagnostic tests (RIDT) in a clinical setting. Evidence for magnetism in the low-temperature charge-density-wave phase of NbSe3. Although the influence of selective cyclooxygenase (COX)-2 inhibitors on the proliferation of colon adenocarcinoma cells have been the subject of much investigation, relatively little research has compared the effects of different COX-2 inhibitors.

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Therefore, the interpretation of functional data using this technology requires further controls and caution. Development of the analysis of phytic acid and other inositol phosphates is described, problems of inositol phosphate determination and detection discussed and the need for standardisation of phytic acid analysis in foods argued. The other patient was a 66-year-old woman who visited our hospital complaining of tenderness and swelling of the fingertips.

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Chronic treatment with desenkephalin-gamma-endorphin (DE gamma E), a beta-endorphin fragment with neuroleptic-like properties, administered s.c. These and other studies are leading to an overall description of the changes which can occur when a protein crystal is irradiated with X-rays at both cryo- and room temperatures. Angiographic regression of coronary atherosclerosis was a secondary outcome. This kind of pigmentation spot model can be used to assess whitening efficacy for whitening or spot-removing products. However, electronmicroscopy of lesions in two patients showed melanocytes undergoing changes resembling those observed in other acquired hypopigmentary conditions.

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It is shown that these structures produce a large number of diffracted waves with similar intensities. In line with our working hypothesis, a sub-chronic 2-week treatment with SC-58236 in the chronic epileptic state kept P-glycoprotein expression at control levels.

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In general, our findings underline the close interrelation between blood supply and successful fracture healing. The devBCA gene cluster (dev for development), shown to be essential for envelope formation in heterocysts of Anabaena sp.

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As the patient did not improve, a sigmoidoscopy was performed and the diagnosis of ulcerative colitis (UC) was made. A case of plastic restoration of eyelid by means of the round pedicle Assessment of these factors enables prediction of prognosis and, in some cases, also the response to therapy. miR-133b levels were also increased in primary cultured neurons and astrocytes treated with the exosome-enriched fractions released from these MSCs. The purpose of this study was to identify predictors of outcomes.

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We found that an insoluble Cr(VI) compound, lead chromate (PbCrO4), was not cytotoxic nor mutagenic on V79 cells, probably because it is taken up by the cells very slowly, whereas the presence of NTA (2.5 X 10(-3) M in water) elicited a direct cytotoxicity and mutagenicity, which was dose-dependent from 5 X 10(-5) M to 10(-4) M PbCrO4. The purpose of this study is to investigate the temporal relation between the change in the resistive index (RI) from renal Doppler sonography and that of serum creatinine values in the course of experimentally induced reversible acute renal failure (ARF) in rabbits. The xenoestrogen bisphenol A inhibits postembryonic vertebrate development by antagonizing gene regulation by thyroid hormone. Furthermore, the effects of dihydroergotamine have been analysed for comparison. After addition to liposome dispersions, circular dichroism spectroscopy indicated that both peptides undergo an extremely rapid transformation to a beta-conformation that remains unchanged throughout the remainder of the experiment.

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Anomalous origin of the left coronary artery from the pulmonary artery: report of an adult with ventricular fibrillation as the presenting symptom. Following scanning, subjects were asked to pair faces with their corresponding proper name. Localization of NADPH-diaphorase activity in the human visual cortex. The first single-port cholecystectomy took 160 minutes with sequential improvement to the sixth case of 66 minutes with a mean of 68.2 minutes for the last 15 single-port cases. Chitosan-polyvinyl pyrrolidone hydrogel does not activate macrophages: potentials for transplantation applications.

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The four exercise regimens were: running with its onset immediately after injury, running with a 72 hr delay after injury, swimming with immediate onset, or swimming with a 72 hr delay. In vivo studies on female albino mice demonstrated maximum uptake of the drug by mammary tissue after 24h of administration with drug loaded guar gum nanoparticles in comparison with that with the tablet form of the drug. The recent development of a novel system for culturing ovarian follicles in a three-dimensional alginate matrix shows promise in phenocopying in vivo folliculogenesis. In addition, a significant loss of calretinin containing interneurons was observed in the subiculum.

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We treated newborn C57BL/6 mice orally with 35 mg/kg phenytoin (PHT) daily during postnatal days (PD) 5 to 14. Establishment of institutional antimicrobial stewardship programmes (ASPs) is advocated as a key intervention to reduce antibiotic consumption in hospitals and address high rates of multi-drug-resistant (MDR) bacteria. Vessel injury is considered to be the most threatening complication. The effect of thrombolytic treatment on the development of global and regional left ventricular function To compare the sensitivity of volume scanning with optical coherence tomography (OCT) to nonmydriatic color fundus photography (FP) for the detection of retinal irregularities in asymptomatic populations.

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flexible cystoscopy, urethral dilatation, and urethral catheterization for retention, for urodynamics or for intravesical chemotherapy. Chimeric viruses were produced by co-transfection of a V1-V3 deleted pNL 43 vector and PCR fragments spanning the deleted region, amplified from HIV-1 RNA positive seminal plasma samples. For future applications, the process model can be used to ensure enough extraction capacity from aqueous to octanol phase. Tissue channels as a part of microcirculation system have been proposed over three decades, playing an important role in fluid transportation as reported. A rare complication of tuberculous meningitis pediatric anterior glenohumeral instability.

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The future role of CLP and combined medical-psychiatric units in an era of managed care is also discussed. The significant inhibition by OPZ of human recombinant yeast CYP1A2 and CYP3A4 was also shown. The present report describes a novel etiological agent of cutaneous leishmaniasis in horses that, at least for some cases, sporadically appeared as autochthonous infections in geographically distant regions of Germany and Switzerland. Perfluorodecalin and silicone oil used to achieve retinal tamponade left in an eye for 6 months. The percentage of patients with low nuclear grade and favorable histology was generally lower for patients with palpable lesions compared with those having nonpalpable lesions and decreased as lesions got larger.

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The delay in State 3 rates was more prolonged in liver than in heart at comparable palmitoyl-CoA levels. The potential contributing factors to the stent thrombosis are analyzed. Risk of Non-melanoma Skin Cancer in Patients with Chronic Kidney Disease and its Relationship to Uraemic Pruritus. Methodologically the organization of the therapeutic process is based on principles of rehabilitation which bring together medical, social, and psychological measures. Spectral properties of plant leaves pertaining to urban landscape design of broad-spectrum solar ultraviolet radiation reduction.

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G-CSF treatment did not alter the parasite load but caused an increase in the number of apoptotic inflammatory cells in the heart. Large lung bullae are a rare manifestation of pulmonary sarcoidosis. Data on sample, size, types of patients duration of study, types of acupuncture, definition of adverse events, method of evaluation, and findings were extracted systematically from the retrieved reports. Provided the mother of the neonate consents to the use of the umbilical cord blood, this material can provide a useful resource without any further complicating critical or ethical concerns.