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Finax (Finasteride)
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Finasteride

Finax works by inhibiting type II 5-alpha reductase, the enzyme that converts testosterone to dihydrotestosterone (DHT). This converted form of testosterone stimulates development of the penis, testes and scrotum, as well as other male sexual characteristics such as body hair and pubic hair. DHT also promotes growth of the prostate. In 1992, Finax 5 mg per day was approved by the U.S. Food and Drug Administration (FDA) as a treatment for benign prostatic hyperplasia. The agent was marketed by Merck under the name Finax. Patients need to allow at least 6 months for the therapeutic effects to be determined. Symptoms that may improve include difficulty urinating, increased urination frequency and decreased urinary flow. If the therapy is discontinued, symptoms will return within around 6 to 8 months. In 1997, Finax 1 mg per day was approved by the FDA as a treatment for male pattern baldness and this time the agent was market by Merck as Finax. Finax 1 mg per day was shown to benefit men with mild to moderate hair loss in a five-year study. Two thirds of the men who took the medication on a daily basis saw some regrowth of their hair, while those who did not take the medication experienced further hair loss. Analysis showed that for all five years of the study, the average hair count remained above baseline among the Finax group and was increased compared to those who did not take the treatment. The medication is only effective for as long as it is used, with the therapeutic effects being lost within 6 to 12 months after discontinuation of the therapy.

Other names for this medication:
Finasteride, Androfin, Avertex, Daric, Fenered, Finahair, Finalo, Finalop, Finar, Finara, Finast, Finax, Fincar, Finpecia, Firide, Monast, Prohair, Propecia, Proscalpin, Proscar, Prosteride, Reduprost, Renacidin, Sutrico, Symasteride, Tealep, Tensen,

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Thus, surgical intervention can be avoided with adequate pain control, allowing the herniation time to regress. Molecular cloning and sequencing of feline stromal cell-derived factor-1 alpha and beta. The presented case report refers to a rare finding of ectopic liver forming mesodermal cyst within the umbilical region. Biofabrication of antibodies and antigens via IgG-binding domain engineered with activatable pentatyrosine pro-tag.

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Using live imaging in brain slices, neural stem cells and their progeny labeled by in utero gene transfer can be monitored at high spatial and temporal resolution for as long as several days. Because patients with tuberculosis of mesentric lymph nodes show no characteristic manifestations, laboratory methods (e.g. Note on comparison of small proportions in large-scale experiments. Rates of the rotenone-insensitive respiration increased substantially on both a fresh-weight and extractable-cellular-protein basis 24 h after rotenone treatment. Systematic literature review of all published epidemiologic studies on skin cancer in scar tissue from surgery, ulcers, or burns using citation databases and manual review.

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Presentation of a modified dispersion model (MDM) for hepatic drug extraction and a new methodology for the prediction of the rate-limiting step in hepatic metabolic clearance. Volleyball injuries: a survey of injuries of Scottish National League male players. The one effect observed exclusively in cocaine-treated FR rats was increased p-Ser845-GluA1 in nucleus accumbens. In vitro anti- and pro-oxidative effects of natural polyphenols.

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Finally, a strong correlation has been found between plasma NOV/CCN3 concentration and fat mass. Deletion of T-cell receptor V beta families following human renal transplantation. The neuronal calcium-sensor protein VILIP modulates cyclic AMP accumulation in stably transfected C6 glioma cells: amino-terminal myristoylation determines functional activity.

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This fast differential response is uniquely mediated by focal adhesion protein zyxin at low shear stress and actomyosin fibers of the actin cap. In our article we analyzed 43 cases of patients with variceal bleeding treated in our clinic in 2002-2008. In the mechanism, Lys-262 polarizes the peptide carbonyl group, which is also coordinated to Zn1.

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There are many factors that may influence presentation for stroke and awareness of the warning signs may be only one. Microsurgery and danazol therapy both were effective in preventing residual endometriosis, but the animals tended to be less fertile after treatment. Global-scale patterns of nutrient density and partitioning in forests in relation to climate.

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This article reviews the literature about the use of ATG and alemtuzumab for the treatment of acute rejection after renal transplantation. Here, we show that an enantiopure sulfoxide can be produced from the corresponding racemate using Viedma ripening involving rearrangement-induced racemization. One chitinase gene-containing clone (named pCHT1) was selected from about 8000 recombinants on chitin overlay plates. The F-box protein FBW7/hCDC4 is a tumor suppressor that acts as the substrate recognition component of an SCF ubiquitin ligase that targets numerous oncoproteins for proteasomal degradation. Using a large-scale dairy farm survey containing information from 2005, we apply a data envelopment analysis method to estimate technical efficiency of the dairy farms.

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The model can be run online at the JWS Online database (http://jjj.biochem.sun.ac.za/database/uys). Recently, microglial activation has been implicated in the development of nerve injury-induced neuropathic pain. An analysis of the hemodynamic consequences of the injections of long linear polymers with high molecular weight is introduced.

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This case report describes an episode of postoperative myocardial ischaemia after total oesophagectomy that was successfully treated by extradural administration of local anaesthetic. The main outcomes were the duration of labour and induction to delivery interval. An experimental comparison with existing contour-based registration methods and an intensity-based registration method has been performed. Deglabration in bi-temporal erythemato-squamous plaques: a case for diagnosis

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Titanium miniplates were used to stabilize fractured bones and a bone graft in 14 patients. Sympatho-adrenal system involved in the inhibitory effects of nicotine on the vagally stimulated gastric acid output and mucosal blood flow in rats.

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In eyes with early glaucoma, RNFL thickness was decreased significantly in eight of the 12 peripapillary sectors, and macular volume was decreased significantly in six of the nine macular sectors, compared with normal eyes. The left-right body axis is defined relative to the dorsal-ventral and anterior-posterior body axes. Comparison of nontumorigenic and cancerous lines suggests that a loss of the alpha 4-subunit correlates with the acquisition of tumorigenicity and perhaps metastatic potential. To measure the relationship between blood flow and central venous pressure (Pcv) and to estimate mean systemic filling pressure (Pmsf), circulatory compliance, and stressed volume in patients in the intensive care unit. Positive-projection Monte Carlo simulation: A new variational approach to strongly interacting fermion systems.

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We conclude that written instruction appears to be inadequate to achieve safe and effective administration of inhaled medicine. The anlage of a fissure begins in a well-determined place of the cerebellar cortex. Verification of blood glucose concentrations in ferrets with a laboratory analyzer is highly recommended.

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This activity was confirmed in vivo in the 8 h zymosan-injected rat air pouch, on the secretory enzyme accumulating in the pouch exudate. Handling of adolescent rats improves learning and memory and decreases anxiety.

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In addition, with pattern recognition analysis of urinary metabolites, the results showed a clear separation of the model group and control group, while XY-A group was much closer to the control group in the OSC-PLS score plot. Slow drying reversibly led to both alpha-helical and intermolecular extended beta-sheet structures. Preincubation of spermatozoa with an anti-L-selectin monoclonal antibody produces a significant inhibition of zona pellucida tight binding, under hemizona assay conditions. We found significant correlations between exercise capacity and respiratory parameter values, but PESE was correlated with only gait speed and RPE.

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Administration options for pegfilgrastim prophylaxis: patient and physician preferences from a cross-sectional survey. At 48h after ligation, a significant amount of the axonal transport of EP24.15 activity was found in the proximal segment, while axonal transport of deamidase activity, a lysosomal enzyme, increased in both proximal and distal segments.

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The impact of healthy start peritoneal dialysis on the evolution of residual renal function and nutrition parameters. The subjects were 278 patients older than 15 years of age and who had given informed consent The questionnaire contained 71 questions concerning the following seven characteristic factors: sense of hearing, sense of sight, sense of smell, sense of taste, sense of touch, sense of pain, and other situations. This conditioned production of antibodies of IgM and IgG isotypes is similar to that found in secondary responses elicited by reinjection of antigen. In antibody-injected cells, the epitope remained expressed at kinetochores throughout the prolonged metaphase, but had disappeared by the onset of anaphase. Identification and characterization of simple sequence repeat markers from a glandular Origanum vulgare expressed sequence tag.

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We performed a prospective, multicenter study comparing capsule endoscopy with optical colonoscopy (the standard for comparison) in a cohort of patients with known or suspected colonic disease for the detection of colorectal polyps or cancer. n-oxPTH was separated from its oxidized form using an affinity column capturing the oxidized PTH. Propranolol was bound by the membrane, but there was a larger, continuous loss to the o-ring. Despite the availability of rubella vaccine the incidence of the congenital rubella syndrome has been increasing in certain regions of Canada. Eligible patients at National Cholesterol Education Program-Adult Treatment Panel III LDL-C treatment goal on a statin, with or without other lipid-modifying medications, are treated with anacetrapib, 100 mg, or placebo for 18 months, followed by a 3-month, poststudy follow-up.

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Journal Honors Andrew Lane, MD, PhD, As Recipient of the 2012 JCO Young Investigator Award. Peripheral blood monocytes secrete prostaglandins before MS attacks.

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The solution structure of mamba intestinal toxin 1 (MIT1), isolated from Dendroaspis polylepis polylepis venom, has been determined. Two patients suffered early postprocedural orbital hemorrhage requiring treatment with lateral canthotomy and inferior cantholysis. We have set out to produce a comprehensive comparative map between human chromosome 9 (HSA9) and the laboratory mouse. Additionally, absence of change in drain output does not rule out presence of AL.

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In addition, PGA conformation could be reversibly manipulated as a function of environmental changes such as pH and ionic strength. Moreover, inflammatory response to UV exposure may further contribute to skin carcinogenesis by oxidative stress mechanisms.

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A microradiographic study of developing staphylococcal inflammation using ultra-soft roentgen rays. When subjects engage in an overt semantic comparison task with a clearly visible target numeral, measures of covert motor activity indicate that they also unconsciously apply the task instructions to an unseen masked numeral. The Rural Organisation of Australian Stroke Teams (ROAST) project sought to promote the evidence-based stroke practice in rural hospitals. An incomplete duplication affecting only the anterior pituitary gland or the pituitary stalk has not been described so far.

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Ministries of Health are changing their central reporting health information systems to health management information systems with emphasis on managers utilizing information at the point of collection. Levels of sucrose, glucose, and fructose were compared between wild-type and sxd1 plants. Genetic diversity within the genus Trichinella as shown by cleavage fragment length polymorphism analysis. This treatment is designed to minimise the problem of weight regain by addressing psychological obstacles to the acquisition of, and long-term adherence to, effective weight-control behaviour.

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Validation of echocardiographic two-dimensional speckle tracking longitudinal strain imaging for viability assessment in patients with chronic ischemic left ventricular dysfunction and comparison with contrast-enhanced magnetic resonance imaging. Fertility is limited by associated vaginal malformations, which have traditionally required surgical reconstruction.

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Owing to the previously reported detection of propargyl radical by ESR experiments, in this process a radical mechanism was suspected. As a consequence, phase contrast is detectable even when absorption contrast is minimal or absent. Relations between VAT, SAT, and cardiometabolic risk factors were not fully explained by adiponectin or resistin concentrations.

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High serum levels of B-lymphocyte stimulator are associated with clinical-pathological features and outcome in classical Hodgkin lymphoma. The effects of NO synthesis inhibition on the blood oxygen transport (hemoglobin-oxygen affinity and erythrocyte deformability) were investigated in rats with hyperthermia. We used the pattern-recognition capacity of Purkinje cells based on the Marr-Albus-Ito theory of cerebellar learning to evaluate the suitability of the linear algorithm for cerebellar information processing. However, microscopic examination, the only test usually available in areas of endemicity, has a low sensitivity.

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The high rate of grade-4 hematologic toxicity observed with this highly albumin- bound compound in this patient population provided challenges for fixed Cmax-based dosing. Moreover the insulin-like growth factor type-I receptor localized with the transferrin receptor and Rab11-positive endosomes in a ligand-dependent manner, further supporting the conclusion that this receptor follows a recycling pathway. Hereditary and severity of the clinical picture of patients with diabetes in Nis and vicinity

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Sulfur-nanoparticle-based method for separation and preconcentration of some heavy metals in marine samples prior to flame atomic absorption spectrometry determination. To estimate the prevalence of two types of mild cognitive impairment (MCI)-amnestic and multiple domain types-among nondemented and nondepressed elderly subjects aged 50 and older. The photoinduced dynamics after simultaneous excitation of more than a single chromophoric unit (donor/acceptor) at varying excitation fluence is investigated in this contribution. Estimates of flow were attempted at 101 deliveries and thermal dilution curves obtained at 52.

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Immunological significance of demyelination of medullated nerve fibers of the eye. To evaluate the possible cancer risk for man due to urethane in beverages, the observed response rates were used to extrapolate responses at lower doses. Several 4- and 5-substituted-5H-1,2-oxathiole-2,2-dioxide derivatives were found to have a selective inhibitory activity against human cytomegalovirus (HCMV) and varicella zoster virus (VZV) replication in vitro, being inactive against a variety of other DNA and RNA viruses.

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There is not a gold standard in the treatment of primary gastric lymphoma (PGL). Cyclin-dependent amolin sensitive toothpaste kinase 5 governs learning and synaptic plasticity via control of NMDAR degradation.

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