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Fine structure of tumor cells in the process of transplanting experimental bone tumors Effects of melatonin on adrenomedullary dopamine-beta-hydroxylase activity in golden hamsters: evidence for pineal and dose dependencies. The age of onset was from 6.6 to 15.5 years (average 9.5 years). Correlation between HPV status via in situ hybridization testing on genital squamous papillomas and risk for cervical dysplasia or other anogenital HPV-related complications: A case-control study.

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Using the sequence of the 16S rDNA of the bacterium, we found that the male-killing bacterium is a member of the Flavobacteria--Bacteroides group, most closely related to the male-killing bacterium in another ladybird beetle, Coleomegilla maculata. Population pharmacokinetics of multiple alcohol intake in humans.

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Low observed rates of insect visitation appear to contradict high rates of CH fruit production in open-pollinated plants, particularly given the rarity of delayed selfing. Neomycin-resistant rabbit RPE cells that showed beta-galactosidase activity were generated within 2-5 weeks. The purpose of this paper is to illustrate the application of robust Bayesian methods to the analysis of clinical trials data. The sentences contained a non-adjacent dependency between an auxiliary and the morphologically marked suffix of the verb. Intravenous injection of an HC-Ad vector into a hemophilia A dog at a dose of 4.3 x 10(9) IU/kg led to transient therapeutic canine FVIII levels that partially corrected whole-blood clotting time.

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The critical organs were those that typically take up the most glucose (brain, heart wall and liver). The conceptual simplicity, the availability of gene sequence information from the human genome, the inexpensive availability of synthetic oligonucleotides and the possibility of rational drug design makes As-ODNs powerful tools for target identification, validation and therapeutic intervention. Response-chain learning of mentally retarded adolescents under four conditions of reinforcement. The degeneracy is broken when the molecule is contacted to the leads, giving rise to two resonances that become pinned to the Fermi level and display destructive interference.

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It is well known that both insulin resistance and insulin deficiency are involved in the pathogenesis of post-transplant diabetes mellitus (PTDM), but the relative importance of the two different mechanisms is still under debate. To determine whether maternal plasma concentrations of placental growth factor (PlGF), soluble endoglin (sEng), and soluble vascular endothelial growth factor receptor-1 (sVEGFR-1) at 30-34 weeks of gestation can identify patients at risk for stillbirth, late preeclampsia, and delivery of small-for-gestational-age (SGA) neonates. In human lung carcinoma A549 cells, the release of AA by EGF was insensitive to sorafenib. The majority of programs fall into two categories: accident prevention programs seeking primarily to foster safe driving practices, and recidivism prevention programs seeking primarily to foster lawful driving behavior.

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It has become clear, however, that the presence of mucosal abnormalities does not always correlate with the presence of overt bleeding, or with the effect of bleeding on the overall outcome of such patients. Confronted with rapidly accumulating data, researchers currently do not have the software tools to undertake the required information integration tasks. Based on our experimental findings, we conclude that the analgesic effect of the dual norepinepherine and serotonin reuptake inhibitor, amitriptyline, is partially due to inhibition of central iNOS. Pseudomyxoma peritonei associated with mucinous cystadenoma of the appendix

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Direct electrical stimulation as an input gate into brain functional networks: principles, advantages and limitations. To assess the association between intention to quit smoking and perceptions of household environmental risks among racially/ethnically diverse residents of low-income housing.

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From an ethical point of view, the decision to accept or decline a test not requested has to be made autonomously. The cutoff for optical density readings was estimated by testing of 145 sera from healthy subjects. We used conditioned place preference to concomitantly determine the presence of tonic pain in rats and the efficacy of agents that relieve it. We developed a method which is effective in removal of the agarose contaminants.

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The diagnosis of the aneurysm was mainly based on computed tomography scan findings. Contrast sensitivity functions (CSFs) were measured in the foveal region while subjects simultaneously performed an instantaneous judgment task, which was designed to maintain their attended areas at a constant size. oxysporum strains transformed with an expression vector containing the prt1 coding region fused to the inducible endopolygalacturonase pg1 gene promoter and grown under promoter-inducing conditions secreted high levels of extracellular subtilase activity that resolved into a single peak of pI 4.0 upon isoelectric focusing. Critical points of the assay, such as cell fixation and permeabilization, specificity, and sensitivity, were systematically investigated by using four oligonucleotides newly designed to target groups of cyanobacteria. Our data have demonstrated the indispensability of Ankrd17 functioning for vascular maturation during early development.

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Multiple chromosomally distinct cell populations in myelodysplastic syndromes and their possible significance in the evolution of the disease. Antigenic variation in Lyme disease borreliae by promiscuous recombination of VMP-like sequence cassettes. Concurrently, zebrafish facility managers can contribute to the progress of a semiannual facility inspection by maintaining fully accessible operating records.

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Identification and quantification of intermediates of unsaturated fatty acid metabolism in plasma of patients with fatty acid oxidation disorders. We investigated the role of B cells and antibodies in the development of atherosclerosis in low density lipoprotein (LDL) receptor-deficient (LDLR(-/-)) mice. We report here that 5-HT activates Smads 1/5/8 in bovine and human pulmonary artery smooth muscle cells (SMCs) and causes translocation of these Smads from cytoplasm to the nucleus. The main difference lies in the absence of serious internal (cardiac) abnormalities in adult WHS.

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There were no significant differences with regard to efficacy and tolerability of LEV and LTG in newly diagnosed focal and generalised epilepsy despite more rapid titration in the LEV arm. Drawing on work done in the EU FP6 projects PROSAFEBEEF and Q-PORKCHAINS and a Danish project, all dealing with new product development in the meat sector, it is shown how the use of consumer insight techniques can a) support the identification of market opportunities, b) make sure that technologies applied are acceptable to consumers, c) aid the selection and optimisation of new product concepts and related communication, and d) be used to test product prototypes before final launch. Unsolved questions regarding the identity of mesenchymal stem cells have not compromised the consideration of these cells as outstanding candidates for cell therapies. This study evaluated the risk of failure for an endodontically treated premolar with mesio occlusodistal palatal (MODP) preparation and 3 different computer-aided design/computer-aided manufacturing (CAD/CAM) ceramic restoration configurations.

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Surgically documented segmental medullary sponge kidney: case report. Steady-state (8-Hz) pattern electroretinograms in response to counterphased sinusoidal gratings of variable spatial frequency (0.6-4.8 c/deg) were recorded in 17 patients who had had retrobulbar optic neuritis in one or both eyes (23 eyes with a clinical history of optic neuritis) and in 21 age-matched normal subjects. To address these questions, we generated mice in which the NR1 S897 is replaced with alanine (A).

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Nevertheless, further in vitro and in vivo studies are essential before thioridazine may be recommended for the management of select cases of pulmonary tuberculosis. Preventive effects of sevoflurane treatment on lung inflammation in rats. Our results indicated deterioration in some cognitive abilities at baseline with further decline in this area found after 10 years.

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To further test this relationship between sodium transport and autoimmune hearing loss, dosage comparisons were made of prednisolone and aldosterone control of the auditory dysfunction in autoimmune MRL/MpJ-Fas(lpr) mice. The histopathological changes showed damage to epidermis and dermis. Compartment syndrome of the forearm is a serious medical problem, and it is commonly associated with high-energy injuries to the upper extremity. Doppler parameters were analyzed, including peak systolic velocity (PSV) in the iliac artery, PSV at the arterial anastomosis, PSV in the transplant renal artery, PSV ratio of the stenotic artery/artery proximal to the stenosis, and acceleration time (AT) in the artery distal to the stenosis (in the intrarenal artery). To investigate disease processes, lung slices can either be prepared from animal models of disease or animals exposed to disease invoking conditions.

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With larger configurations, some adjustments to the simple models are necessary to account for the presence of the gaps. Salt and osmotic stresses induce expression of some CK biosynthetic genes in seedlings of maize, leading to a moderate increase of active forms of CKs lasting several days during acclimatization to stress. Phosfinder is a web server for the identification of phosphate binding sites in protein structures. In the mid-1970s the World Health Organization (WHO) introduced a scheme for the measurement of the consequences of disease. The first experiences of clinical practice of psychiatric nursing students in Taiwan: a phenomenological study.

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Baseline data were continuously collected in tethered but relatively freely moving mice for 2 days. It has both preventive and therapeutic importance, for the individual as well as for the public. Stimulated Raman scattering (SRS) and laser-induced breakdown (LIB) are simultaneously observed in acoustically levitated millimeter-sized glycerol droplets irradiated by either a frequency-doubled (532-nm) or a frequency-tripled (355-nm) Nd:YAG laser. This study provided the first direct comparison between the HIV-1 quasispecies archived as provirus in circulating monocytes and T lymphocytes with that of plasma virions replicating in the same cell types.

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The goal of this study was to evaluate the role of surgical resection for patients with brain metastases and to find the best indications for SR. Estradiol and progesterone-induced slowing of gonadotropin-releasing hormone pulse frequency is not reversed by subsequent administration of mifepristone. Behavioral reactivity was greater in BALB/cByJ mice with respect to open-field emergence, step-down responding, response to a predator (rat) or to fox urine odor. The computed tomography and magnetic resonance imaging features of this unusual form of pelvic fibrosis as well as the association with heterotopic fibrosis are discussed.

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By contrast, neither enzyme was immunolocalized in the reproductive organs, vitelline glands, nor gynecorphoric canal. 16 alpha-hydroxyestrone was rapidly eliminated, again without detection of further degradation products. Furthermore, the strength of functional coupling (ERCoh) between midfrontal and right-frontal electrodes was a good predictor of WCST behavioural parameters, such as the percentage of perseverative errors or the number of categories achieved. Studies with various aminopyrine solutions on fibroblast cultures

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Adding layers of ITO to the structure further shifts the resonance wavelength toward the IR region and, depending on the sequence and thickness of the layers within the structure, we show that such structures can be applied in sensing devices including enhancing silicon as a photodetection material. Demonstration of a new free-electron-laser harmonic interaction. A higher CNR can be obtained with Gd-DTPA on a 1.5T MRI scanner. Hemagglutinin loss by vaccinia virus and its relationship to virus adaptation in tumor and L cells. Although equieffective doses (IC50) of 5-FU were used, resistance to a 1 h exposure of 5-FU developed faster in all models than to a 24 h exposure.

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Ketamine, a non-competitive NMDA receptor antagonist, has in several case reports given pain relief but efficacy in dosages tolerated in long-term ketamine treatment is unknown. Influence of heparin thromboprophylaxis on plasma leucocyte elastase levels following lobectomy for lung carcinoma. Comparison with samples of 30 patients who had been randomly assigned to IND and 30 to INT did not confirm the hypothesis that patients who chose their treatment would either remain in treatment for longer periods of time or manifest improved 9-month outcomes. Neutralization activity data were obtained from 11 laboratories on a coded panel consisting of six human MAb to HIV envelope V3, CD4-binding region or gp41.

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An investigation of results of 82 many-stage operations and 241 one-step operations has shown advantages of the former as giving less postoperative lethality. Electrocardiographically-assisted imaging is a recent development in multislice spiral computed tomography. The patient was a 56-year-old male who had been treated for diabetes mellitus for 17 years.

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Transition from intravenous to subcutaneous insulin: effectiveness and safety of a standardized protocol and predictors of outcome in patients with acute coronary syndrome. Antioxidants vitamin E and 1-aminobenzotriazole prevent experimental non-alcoholic steatohepatitis in mice. These data indicate that Mcl-1 is an important target for flavopiridol-induced apoptosis of MM that occurs through inhibition of Mcl-1 mRNA transcription coupled with rapid protein degradation via the ubiquitin-proteasome pathway. The main objective of this study is to develop microencapsulation technology for thermal energy storage incorporating a phase change material (PCM) in a composite wall shell, which can be used to create a stable environment and allow the PCM to undergo phase change without any outside influence. We chose suit weight functions for different texture images, and used the proposed method for image segmentation.

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The presence of endotoxemia is relatively common in cardiac surgery patients and it may modify the metabolic and hemodynamic responses peri- and postoperatively. Education in diagnostic radiology employs medical images extensively, and case-based teaching files of actual patients are useful to illustrate pertinent teaching points. Six months later, patients were contacted to complete outcome questions about accumulated sick leave.

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The association of pancreatoblastoma and Wiedemann-Beckwith syndrome has not been noted previously. On the basis of the kinetic equation of substrate reaction, a general procedure is developed for determining the kinetic constants of dissociating-associating enzyme reactions.

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Corneal endothelial cell proliferation under our culture conditions is noted primarily when cell density is less than 2000 cells/mm(2). A three-cell cluster hypothesis for noncognate T-B cell collaboration via direct recognition of allogeneic dendritic cells.

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The present study examines the effect of ultrasound exposure on the central expression of the immediate early gene c-fos in the rat, in order to examine the brain structures activated by such behaviour. Quantitative visualization of nanoparticles in cells and tissues, while preserving the spatial information, is very challenging. Treatment was performed either by bronchoscopic intratumoral injection or by CT-guided percutaneous intratumoral injection of the vector solution.

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Methyl anthraquinone (tectoquinone) a synergist for 2,2-bis-(p-chlorophenyl)-1,1,1-trichloroethane (D.D.T.). The intervention included classroom instruction, distribution of hearing protection devices, direct mailings, noise level assessments, and yearly audiometric testing.

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This paper illustrates these issues by assessing the relative cost effectiveness of 3 nonsteroidal antiinflammatory drugs (NSAID), with different levels of gastrointestinal side effects, in 3 countries. Exposure to intense solar radiation in youth significantly increases the lifetime risk of developing melanoma. The overall conformation of imatinib when bound to NQO2 resembles the folded conformation observed in some kinase complexes. Although most patients are treated by percutaneous drainage, some cases require operative intervention. Chewing the fat over statins: Consumer concerns about lipid-lowering medication.

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The use of flow field flow fractionation (FlFFF) for the separation and characterization of natural colloids and nanoparticles has increased in the last few decades. The WaveScan and LADARWave share similar lower order aberration measurements, but display significantly different higher order aberration values.

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Topotecan plus ara-C is equivalent to topotecan alone in chronic myelomonocytic leukemia (CMML), but significantly more effective in RAEB and RAEB-t. The patients were then stratified by type and severity of hearing loss, and otologic issues were documented. Both antisera and the gst-Vpr expression plasmid have been submitted to the NIAID AIDS Research and Reagent Program and are available to interested investigators.

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Two cases of fungal infections caused by Trichosporon asahii var. Aspects of the reports of the 1st Latin American seminars on the teaching of dentistry relative to the subject analysis and recommendations on Latin American dental curricula

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DeMSum verifies a manuscript (MS) by processing the MS attributes that are accessed through the editorial system. Electron capture gas chromatographic detection of thromboxane B2.

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The cytokinesis-block micronucleus assay (CBMN) in G0 peripheral blood lymphocytes was carried out using the cytochalasin B technique. The double graphene/PMMA stack has proved to be significantly better than single graphene/PMMA stack and bilayer graphene/PMMA structures, providing a polarizer with maximum extinction ratio of 44 dB for a length of 4 mm. In this article, the indications, technique, predictors of failure, outcomes, and complications are reviewed. 42 consecutive patients with idiopathic PD treated with bilateral STN stimulation were enrolled.

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Characterization of natural variation in North American Atlantic Salmon populations (Salmonidae: Salmo salar) at a locus with a major effect on sea age. Some characteristics of the structure of the active surface of cholinesterase from the optic ganglion of the squid Surgical treatment of uterine myoma: need for surgery and long-term results Defects in 11 beta-OHSD1 may be important in essential hypertension, and polycystic ovarian syndrome. Spacer oligonucleotide typing of bacteria of the Mycobacterium tuberculosis complex: recommendations for standardised nomenclature.

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Since ABC transporters function to export solutes and alpha-TP is transported into cells, it may be concluded that alpha-TP transport may occur via an OAT family member. Furthermore, rpoZ-disrupted mutant R6D4 obtained from strain A1R6 by insertion of Tn5 aphII into the middle of the rpoZ-coding region produced neither kasugamycin nor aerial mycelia, similar to mutant KSB.

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Current practice and attitudes of Australian obstetricians toward population-based carrier screening for inherited conditions. A SIRT1-LSD1 corepressor complex regulates Notch target gene expression and development. The other ORFs encode for four structural proteins (spike, membrane, nucleocapsid and envelope) as well as eight SARS-CoV-specific accessory proteins (3a, 3b, 6, 7a, 7b, 8a, 8b and 9b). A 48-year-old woman with aortitis syndrome underwent clipping of dissecting aneurysm of the left posterior inferior cerebellar artery following subarachnoid hemorrhage. In this investigation, the dimensionality and complexity of the tutor role were assessed by first- and second-year dental students and by the tutors themselves using a twenty-four-item Likert-type questionnaire that served as one component of a comprehensive web-based assessment tool, the PBL-Evaluator.

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The urethral plate can be preserved in most cases of posterior hypospadias (35/43) and dorsal plication of the corpora cavernosa is rarely needed. Three classes of steroids in typical freshwater aquaculture farms: Comparison to marine aquaculture farms. A prospective study was performed when MEM was introduced as a trial in an urban ambulance service in Norway. Akt1 is critical for acute inflammation and histamine-mediated vascular leakage.

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Judicious manipulation of FT could benefit cotton architecture to improve crop management. It is well documented that tumors in the Ganglioneuroblastoma, nodular (composite, Schwannian stroma-rich/stroma-dominant and stroma-poor) category are composite and composed of multiple clones. A stopped-flow clinical analyzer in which immobilized-enzyme reaction loops are used. To determine if these effects were related to the property of Nef-mediated downregulation of CD4, growth curves of these viruses were determined using cells that express a CD4 molecule unable to respond to Nef.