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Baclofen
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Baclofen

Baclofen Tablets contain the active substance Baclofen, which is a muscle-relaxant drug. Baclofen is used to reduce and relieve the excessive tension in your muscles (spasms) occurring in various illnesses such as cerebral palsy, multiple sclerosis, cerebrovascular accidents, spinal cord diseases and other nervous system disorders.

Other names for this medication:
Baclofen, Lioresal, Baclofene, Baclofeno, Baclon, Baclopar, Barambo, Clofen, Kemstro, Liofen, Lyflex, Miorel, Pacifen,

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Analysis of covariance and multivariable-adjusted linear regression models were used to investigate the associations between these parameters, accounting for the survey design. Despite this, there is a dearth of literature on scaffold formation via melt electrospinning. PARP inhibition was determined by an enzyme assay and DNA damage by the comet assay.

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Irbesartan, an AT1 antagonist, prevents fibrosis and inflammation and inhibits nitric oxide production in HOCl-induced models of systemic fibrosis. Effect of tunicamycin on expression of epitopes on Japanese encephalitis virus glycoprotein E in porcine kidney cells. However, in classical collimation configurations, they remain limited by the trade-off between spatial resolution and sensitivity. tarda could be separate into two kinds of genotypes (genotype I, EdwGI and genotype II, EdwGII) based on the sequence similarity.

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Liver biopsies from the same patients were examined for the histologic activity index (HAI) and the degree of fibrosis. The present UK criterion standard for assessing children with suspected inflammatory bowel disease (IBD) is upper endoscopy, ileocolonoscopy, and barium follow-through (BaFT). Chemicals used to clean nappies have been suggested as a cause of sudden infant death syndrome (SIDS). Technic of blood specimen collection in reptiles: Ophisaurus apodus (Pallas), Scheltopusik

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Apoptosis was triggered either by Fas ligand (FasL) or by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and was monitored by detection of cleavage of procaspase-8 and procaspase-3, as well as their substrate poly(ADP-ribose) polymerase (PARP). Overexpression of RraA circumvents the effects of an autoregulatory mechanism that normally maintains the RNase E cellular level within a narrow range, resulting in the genome-wide accumulation of RNase E-targeted transcripts. Both health effects and social effects can impact on school absence rates.

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The Beckwith-Wiedemann syndrome is most commonly characterized by macroglossia and abdominal wall defect(s), and it carries a predisposition to embryonal tumors, including Wilms tumor. Therefore, the present data suggest that manipulation of endogenous CB1 receptor agonist levels in these areas may significantly reduce nociceptive input into the spinal cord. The size effect in corrosion greatly influences the predicted life span of concrete infrastructures.

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Focusing on regions of viral proteins that are highly conserved across virus subtypes, vaccine strategies involving the matrix 2 protein, stalk domain of the hemagglutinin, and multivalent approaches have provided broad-based protection in animal models and show much promise. In this review, we discuss the different aspects of intratumor angiogenesis and vasculogenesis, the known mechanisms involved, and the possible implications for the response to antiangiogenic therapy. We hypothesized that the wild-type and mutant mice may exhibit spontaneous epileptogenicity as compared with normal (nontransgenic) mice. Pregnancy following radical vulvectomy for carcinoma of the vulva: a case report and literature review.

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Here, we present PASH with MGC occurring in the left breast of a 39-years-old woman who does not have neurofibromatosis. Unaltered size of right ventricular infarct in dogs with right ventricular hypertrophy induced by pressure overload. The manner in which the clathrate aggregate can arrange in the solid indicates that ice occupies the interstitial space in the tightly packed aggregates and H(2)O molecules belonging to the lattice of one form hydrogen bond with that of the other, a feature that is preserved in their collapsed states.

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Comparative sperm chromatin structure assay measurements on epiillumination and orthogonal axes flow cytometers. The complex antibacterial natural product, pleuromutilin, can be directly modified by the radical addition reaction of various xanthates to the unactivated terminal olefin present on C-12. Nonclinical toxicity of the grafted copolymer excipient PEG-PVA. Decreased omentin-1 expression has been found in many chronic inflammatory diseases. Distribution of ferroportin1 protein in different regions of developing rat brain.

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Although the long-term care setting presents challenges to effective management, an approach for addressing these challenges is discussed and applied to 3 commonly encountered nonpain symptoms. These data support our hypothesis that smoking patients treated with nifedipine could be at a potential risk in developing a high pain threshold and missing the first sign of heart attack--a chest pain.

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The field of radiation oncology has evolved, especially in the past 20 years. The sensitized high iron diamine (S-HID) procedure resulted in positive reactions of varying intensities in the intercellular matrix of synovial intima, and in the extracellular matrix and small capillary walls of the superficial layer in the synovial subintima, and also reacted vividly in the extracellular matrix and blood vessel walls of the deeper layer in the synovial subintima. The transcription factors Elk-1 and SAP-1 bind together with serum response factor to the serum response element present in the c-fos promoter and mediate increased gene expression. These three subscales formed the basis of a single measure, labelled the Core Bereavement Items (CBI), which demonstrated high reliability and sound face and discriminant validity. Correlations between low-density lipoprotein cholesterol (LDL-C), or nonhigh-density lipoprotein cholesterol (non-HDL-C) and apolipoprotein B (Apo B) change after statin therapy has been initiated in hypercholesterolemic patients.

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The current study utilizes transmission electron microscopy (TEM), enzyme histochemistry, and high voltage TEM (HVEM) with 3D tomographic reconstruction to both visualize the structure of the MIN and demonstrate that the MIN is a Golgi-related structure. This review will also highlight the importance of prompt resumption of cardiac aspirin and dual antiplatelet therapy following endoscopic hemostasis to minimize the risk of future cardiac events. Reproducibility of the diagnosis of dysplasia in Barrett esophagus: a reaffirmation. They are critical to normal cellular function, and bioinformatic predictions indicate that at least one third of all messenger RNAs might be regulated by miRNAs. Mitochondrial cytochrome c oxidase as a target site for cephalosporin antibiotics in renal epithelial cells (LLC-PK(1)) and renal cortex.

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Majority of neurons recorded in these nuclei exhibit elevated discharge rates during sleep. Multivariate prediction models were developed to identify factors associated with total gestational weight gain and excessive gestational weight gain (i.e., higher weight gain than recommended by the Institute of Medicine). Evidence for Anderson-Brinkman-Morel-type state in a heavy-fermion superconductor from ultrasonic attenuation. Fusion assessment of posterior lumbar interbody fusion using radiolucent cages: X-ray films and helical computed tomography scans compared with surgical exploration of fusion. Further studies on its characterization and a reevaluation of earlier results.

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Surgical trainee assessment using a VE knee arthroscopy training system (VE-KATS): experimental results. Most current tissue attenuation and scattering factors for 192Ir are valid only to distances of 15 cm or less. Unusual clinical manifestations, rare sites of involvement, and the association of other disorders with hairy cell leukemia. One group, consisting of layers 4 and 6, has geniculate layer A as its only necessary and sufficient input.

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The ecological relevance of this finding is discussed with respect to its impact on the behavior of egg parasitoids. In some fiber pathways and nerves, particularly in the brainstem and spinal cord, the axoplasm of many neuronal fibers expressed ASPA, as did some neurons. To that end, we have developed a conversational bot (computer program designed to mimic human communication) with which participants can chat in a format similar to instant messaging. Mechanisms of cartilage destruction: onset of osteoarthritis research in Germany.

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Although the overall impact of HPV gene infection on expression of these systems remains to be fully elucidated, as in vitro system is characterized which should prove useful in examining interactive mechanisms of HPV with xenobiotic activation in the etiology of squamous cell carcinomas. These results demonstrated that LPS-mediated SAA gene induction in monocyte/macrophage cells is primarily due to the induction of SAF activity. These data help identify significant risk factors associated with seizure-related injuries and so facilitate sensible patient counseling about how the risks of such injuries can be minimized. Second can this group of patients be identified by preconception blood testing? Consistent with these results, TSA administration increased neointimal thickening in a murine model of post-angioplastic restenosis.

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Genotypic analysis of tumor suppressor genes PTEN/MMAC1 and p53 in head and neck squamous cell carcinomas. Taking into account the fact that there is no drug or vaccine for GWD (interventions which operate at within-host scale), the results of our study show that the development of a drug that kills female worms at within-host scale would have the highest impact at this scale domain with possible population level benefits that include prevention of morbidity and prevention of transmission.

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8 patients (7-21 years old) with chronic obstructive hydrocephalus due to tectal plate glioma were investigated before and after successful ETV. Sometimes LIF detector needs to be introduced into DNA analysis.

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Victims of intentional trauma have significantly lower intelligence scores than either nonintentional injury or elective surgery patients. These findings highlight the clinical importance of subsyndromal symptoms occurring after remission in late-life depression. Households may become impoverished, reduce needed health services, and experience reductions in consumption as a result of health shocks occurring during a time when their economic vulnerability has increased. Quantitation by enzymatic assays revealed that the rates of cell loss and establishment differed for the two transformants.

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VKORC1 genotype is a covariate of the relative R/S potency relationship. Study on the pathology and treatment of medial femur neck fractures in tabes dorsalis

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The article focuses on researchers who have just started their first study. Effects of different doses of atorvastatin on human apolipoprotein B-100, B-48, and A-I metabolism. Microscopic examination of the resected specimen revealed multiple microcarcinoids that were all smaller than 2 mm in diameter and not visible with gross examination. Interaction of human mesenchymal stem cells with osteopontin coated hydroxyapatite surfaces. As a result, evolutionary geneticists have acquired considerable understanding of the relationship between patterns of allozyme variation and aspects of evolutionary process.

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Studies on induction of streptomycin resistance by streptomycin in Escherichia coli Virus-specific antibody titres in different phases of hepatitis C virus infection. Contrast-enhanced ultrasound (CEUS) has gained interest because of its ability to gather vascular information in various organs. Recognizing this conceptual difference, we conducted a study to address how to establish a pure NOTES procedure. Some biotechnical and cultural alternatives are discussed which, in combination with biocontrol, may assist in evironmentally compatible management of WCR.

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Three independent observers performed a series of measurements on 2D and 3D reconstruction images using digital software. The most reliable and valid set of descriptors determined in one group was tested in a second group of 1306 patients who had been followed for 6 to 36 months after initial evaluation.

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After genotoxic stress, normal cells trigger DNA repair or, if unable to repair, undergo apoptosis to eradicate the cells that bear the risk of becoming tumorigenic. When planning this surgery the next must be taken into consideration: the age of the patient, general health condition and the size and type of the defect, especially of the bone structures. USG guidance can be used for tracing both guidewire and catheter during the procedure to prevent malpositioning of catheter, thus when done at the right time can prevent complication related to malpositioning and repeated manipulations. The aim of this study is to investigate whether moderately increasing inspiratory resistive loading will impact on sympathetic activity in healthy subjects and COPD patients. Changes in motility in infectious enteritis and its clinical relevance

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Preparation of an amperometric sensor for norfloxacin based on molecularly imprinted grafting photopolymerization. We studied 22 patients who suffered infections after surgery and 54 who did not, analyzing the anesthetic technique used as well as other data on age, sex, concomitant disease, toxic habits, practice of invasive procedures, duration and nature of the surgical procedure and the use of antibiotic prophylaxis.

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This sensitivity analysis relies on properties of the Lagrange function that is associated with the constrained optimization problem, but does not depend on the method used to solve this problem. Combined modality treatment can reduce local recurrence rates even further, and can also reduce the rate of distant relapses and increase survival.

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A 54 year old male with the CREST (Calcinosis, Raynauds, Esophageal hypomotility, Sclerodactyly, Telangiectasia) variant of progressive systemic sclerosis (PSS) presented with vertical diplopia diagnosed as a left superior oblique muscle paralysis. A modest reduction of salt and replacement of SFA with PUFA in food products can significantly reduce the burden of CVD in the adult Finnish population. In addition, the rabbit could be a useful LPS animal model for further study of the effects of inflammation and the underlying mechanisms on sperm characteristics. Following a period of fasting, feeding a normal diet results in a burst of DNA synthesis in the crypts of the colonic epithelium. To quantify the impact of androgen deprivation therapy (ADT) in men with a high baseline risk of skeletal complications and evaluate the risk of mortality after a fracture.

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Evidence indicates that COX-2 may regulate apoptosis and can influence the malignant phenotype. Emotionalism (emotional lability) is a common but distressing phenomenon that occurs frequently in individuals suffering cerebral vascular accidents and other brain diseases. Separation of promethazine and thioridazine using capillary electrophoresis with end-column amperometric detection. It is concluded that DC and OP do not interfere with active transport mechanisms but increase the permeability of the epithelium to sodium.

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nidulans cDNA library, we isolated a positive clone containing a 3,210-bp open reading frame that encoded a putative protein consisting of 1,070 amino acids. Among the various second messenger nucleotides molecules, c-di-AMP was discovered recently and has since been shown to be involved in cell growth, survival, and regulation of virulence, primarily within Gram-positive bacteria. Mono-, co-, and tri-cultivation Transwell models constructed with human brain-derived cells under human serum supplementation demonstrated that co-cultivation of astrocytes with endothelial cells produced the most successful model, as determined by TEER. The hybrid particles were uniform in size, and each one of them contained only one metal nanoparticle at its surface after the experimental procedures had been optimized. The association of p16 hypermethylation in the serum DNA of glioma patients with clinicopathological characteristics was analyzed.

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Mathematical models are useful to assess the impact and costs of BC screening in a specific geographical area. Many studies have attempted to demonstrate that lung cancer screening using chest radiography or computed tomography (CT) identifies patients with lung cancer and reduces cancer-related mortality. Interfacial shear strength (IFSS) of the ED carbon fiber/epoxy composites was higher than that of the untreated case. Modelling suggests that due to the cumulative impact of process variables, there is cause for concern about the effectiveness of FM schemes as currently managed in the UK as a standalone public health measure for the prevention of caries. The patient has been on 10 mg/day of prednisolone for the last 6 months.

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The endogenous cannabinoid, anandamide, has been shown to attenuate naloxone-precipitated opiate withdrawal in rodents. In vitro effects of amylin on carbohydrate metabolism in liver cells. In most cases the tip of the conus was located more caudally than normal, indicating some degree of tethering in fetal life. Neck and torso trauma accounts for a large portion of injuries, and its management is an essential part of training in emergency medicine.

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We sought to determine the utility of TTE in detecting elevated left atrial pressure (LAP) in patients with persistent and longstanding persistent non-valvular AF using directly measured LAP as the reference standard. We find that Scc2/Scc4 resides at previously mapped cohesin-associated regions (CARs) in pericentromeric and arm regions, and that Scc2/Scc4-cohesin colocalization persists after the initial deposition of cohesins in G1/S phase. A high incidence of multisystem injuries and high cervical spine injuries would have made early intervention both dangerous and inappropriate. We have created a software pipeline that will allow researchers to discover relevant genomic data from dbGaP, based on matching TCGA metadata.

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The objectives of this paper are to report on the latest technology updates and related radiation protection issues, to present future directions and define gaps. Neuronal dysfunction in the prefrontal cortex, limbic structures, nucleus accumbens and ventral tegmental area is considered to underlie the general physiopathological mechanisms for substance use disorders. Here reported is an 11-week-old female infant with an incarcerated left direct inguinal hernia containing uterus, both ovaries, and fallopian tubes. Comprehensive surgical staging is encouraged in high-risk histologies, whereas a method of triage should be used to determine who among the low-grade endometrioid histology may benefit from comprehensive staging. Unilateral upper urinary tract obstruction and arterial hypertension.

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Corn bran supplementation of a low-fat controlled diet lowers serum lipids in men with hypercholesterolemia. Results show an increased iGBR at recognition in regions involved in bottom-up processes such as the cuneus and the lateral occipital complex.

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Eurysternum (extra-wide sternum)--a rarely recognized developmental anomaly. To evaluate the efficacy, median time to progression (TTP), quality of life and toxicity in the patients with advanced non-small cell lung cancer (NSCLC), treated with thalidomide plus vinorelbine and cisplatin (NP) or NP alone.

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Several new members of the gelsolin family have been discovered in the past year. Health knowledge, attitudes, and practice (KAP)--a basis for health promotion policy in Israel. Back so soon: rapid re-presentations to the emergency department following intentional self-harm. We propose that annular and lateralizing lesions are important manifestations of hormone-related inflammation and recognition of this linkage can lead to improved immune and reproductive health. Neuropsychological deficits have been reported in association with first-episode psychosis (FEP).

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However, it is largely unknown whether poor glycemic control is associated with the severity of ICAS in diabetic patients. Immunocytochemical studies indicate that PnCyPA occurs in the nucleus and cytoplasm of P.

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Exploring avidity: understanding the potential gains in functional affinity and target residence time of quetiazic 25 mg precious bivalent and heterobivalent ligands. We conclude that silvopasture increases the presence of infection by gastrointestinal nematoda in wild horses, especially by strongyles. Dynamic-contrast-enhanced MRI (DCE-MRI) can estimate the rate at which contrast agents pass from the plasma to MS lesions. Moreover, design and use of isoform-specific antibodies provided preliminary evidence for the existence of splice variants at the protein level.

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Twelve patients with patellar subluxation showed no difference in the alignment of the lateral facet, but differed significantly with regard to alignment of both the ridge and the medial facet with contact at a mean flexion of 55 degrees and 85 degrees, respectively. We examined the group-level patterns and local interactions between individuals in wild, free-ranging shoals of three-spine sticklebacks, Gasterosteus aculeatus. Currently UVR protection is advised to patients as a supportive measure but cannot be prescribed to patients miravirsen sodium citrate as these products are not licensed. Eighteen younger (aged 18-35) and 21 older (aged 65-85) women received forward and backward support surface translations of varying amplitudes and velocities. Clinical and diagnostic problems in angiomyolipoma of the kidney

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Due to its rarity and nonspecific clinical symptoms, the correct diagnosis and proper management are often delayed and not well established. flusenil 150 mg Responsibility of the lateral geniculate nucleus in photosensitive epilepsy: dipole tracing method

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A total of 530 American species of sand flies is presented in an updated checklist, along with their author(s) and year of publication using the classification by Galati (1995, 2003). Furthermore, the number of HUVEC containing HCMV DNA decreased about six-fold between 8 and 48 h p.i., indicating that HCMV DNA is either transported into the nucleus or eliminated. Our results indicate that in omecip cipla webmail certain promoters, COUP-TFs act as auxiliary cofactors for HNF-4, orienting the HNF-4 activation domain in a more efficient configuration to achieve enhanced transcriptional activity. The IL-4 responsive element is also recognized by an interferon-gamma (IFN-gamma)-induced DNA binding protein for which a Mr of 50 kDa has been determined.

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NAS was exomax brown bear package not affected by depletion of the NMD protein hUPF2, and it functioned independently of RNA stabilization. Our multilevel analyses suggested OEE to be the cause of the side effects associated with oseltamivir and revealed the molecular mechanism underlying the stimulated behaviours induced by oseltamivir in some circumstances. In the present work, we studied cultivar variations of Australian-grown Danshen in order to select optimal cultivars for local herbal production. This emerging problem is due to the antiretroviral therapy success that allows HIV-positive patients to live longer.

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Psychological factors had a greater relative predictive power in postrenal transplant health-related quality of life of adolescents than did socioeconomic and clinical characteristics. Predictors of initial nontherapeutic anticoagulation with unfractionated heparin in ST-segment elevation myocardial infarction. Using colour Doppler we were able to differentiate between the true and false lumen in the thoracic and abdominal aorta due mutabase 2 25 precious metal prices to characteristic phasic flow patterns.

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The proposed strategy would also serve as a model for the gabapentin 100mg capsules mfg amneal spironolactone efficient biofunctionalization of other carboxylated carbon-based polymer composite materials with potential applications in the biosensor field. Using coherent anti-Stokes Raman scattering and second harmonic generation on the same platform, we simultaneously imaged mammary adipocytes, blood capillaries, collagen fibrils, and tumor cells without any labeling. This prompted the investigation of the relationship between NSCs/progenitors and the initiation of tumorigenesis. Measurement of adrenal and testicular sex steroids in a sample of army recruits and study of their relation to frequency of orgasms ascertained by questionnaire after potential confounding variables were controlled for.

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No cytoplasmic proteins that associate with these receptors in vivo, or are their kinase targets, have yet been described. The diagnostic significance of the activity of the alkaline phosphatase of neutrophils claripen 500 mg amoxicillin consisted in redistribution of cells by the degree of the enzyme activity. Kinetic isotope effect for ground state proton transfer in the green fluorescent protein: a quantum-kinetic model. Urbanization but not altitude was associated to several dyslipidemia traits, with the exception of high non-HDL-c in high altitude settings.