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We have tested a novel strategy of intracellular immunization to block human immunodeficiency virus (HIV) infection. Consistent with a potential role of this intracellular enzyme in protecting membrane phospholipids against oxidative stress, platelet-activating factor acetylhydrolase II has been shown to translocate from cytosol to membranes in response to pro-oxidative stressors, and overexpression of this enzyme decreases the cytotoxic effects of these agents.

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To increase the cell adhesion activity of 74RGD4, an RGDS-inserted mutant between Val74 and Asn75 of human lysozyme, one more site for the RGD introduction was investigated in the lysozyme molecule. During a similar period the incidence among females increased from 0.33 to 2.56 per million/year. Clinical evaluation of enterosorption in the treatment of diabetics Like a previously characterized bovine mastitis isolate, the standard laboratory strain, RN6390 (wild type), entered the epithelial cells and subsequently induced apoptosis.

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Concentrations of trace elements in the plasma after total hepatectomy in the rat. The gross and microscopic lesions were similar to those seen in field cases of pneumonic pasteurellosis. Fluorescence-guided colonoscopy is known to improve the detection rate but the long-term effects of fluorescence-guided colonoscopy are unknown. This solubilization appears to occur from the hydrolysis of unpolymerized alpha-chain and cross-linked gamma-gamma dimer.

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Thus, chimeric genes incorporating ars coding sequences and heterologous promoters can be used to examine regulated gene expression in C. Eight Thai laborers developed meningitis after eating raw snails (Ampullarium canaliculatus) during the period from September 27 to October 6, 1998. Plant NBR1 is a selective autophagy substrate and a functional hybrid of the mammalian autophagic adapters NBR1 and p62/SQSTM1.

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bieneusi genotypes indicated that most host-adapted genotypes were not amplified by PCR targeting these loci. These results indicate that blood monocytes and alveolar macrophages have different roles and use different mechanisms in cell-induced fibrin formation. The roles and interactions among these transcription factors will be discussed. RRI is independently associated with high dose loop diuretics and their increase during a mid-term follow-up thus suggesting its usefulness in detecting an altered diuretic response in CHF outpatients. Future research in China should move beyond descriptive epidemiology.

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However, the functional significance of this pathway, as well as other transient pathways, is still unknown. Our measurements showed the increase in the contents of intra- and extracellular lactic acid after hyperthermia. The circulation time in the cat, studied by a conductivity method. The time is ripe for a molecular dissection of the links between the two processes. Although this result is preliminary and needs to be replicated and expanded upon, our first experience with this method is effective for decreasing the amount of bleeding.

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In addition, emerging evidence reveals the role of the p53 network in the self-renewal, proliferation and genomic integrity of adult stem cells. The effect of losartan on hepatic expression of 31 profibrogenic and inflammatory genes and components of the NOX complex was assessed by quantitative PCR.

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Molecular medicine: a primer for clinicians--part IX human gene therapy. Information on previous fluoroquinolone use was obtained by interviewing patients and checking their medical files. Nucleoside-diphosphate kinase: structural and kinetic analysis of reaction pathway and phosphohistidine intermediate. They varied in size and shape, and gave rise to narrow channels that coursed to the capsular surface of the gland. Some isolates were recovered from previously unreported sources and exhibited unusual phenotypes or represented the first isolates found outside Europe.

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Thereof, two possible scenarios for the occurrence of this unusual composition were created and discussed. Result of the 24-hour thyroid iodine uptake test (T-24) in normal subjects and in patients with thyroid diseases Forced selection of tRNA(Glu) reveals the importance of two adenosine-rich RNA loops within the U5-PBS for SIV(smmPBj) replication. Cultivated human EC and SMC either were transduced with a murine leukemia retroviral vector (MFG) containing the human tPA gene and, in the case of controls, the lacZ gene, or they were exposed to media alone.

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We live in the age of internationalism and the Norwegian physicians and their Society must adapt to it The method was validated and found to be specific, linear, precise, and accurate. We recommend that experimenters take this matter into consideration and, at the very least, ensure the presence of a clinician with hypnotic experience during the administration of the WSGC. Hypolipidemic effects were investigated in both plasma and tissues.

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Although a number of potential cellular targets of artemisinins have been proposed, they remain to be verified experimentally. A 32-year-old male was referred to intensive care with possible respiratory sepsis 15 days after sustaining 73 per cent TBSA electrical burns. The favored adsorption geometry for four Na and four Cl atoms was found to be an adsorption of four NaCl dimers due to the formation of Cl-Si bonds. Applying aggressive treatment as outlined in our strategy may improve the chances of long-term survival.

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Studies dealing with the economic burden of musculoskeletal diseases and the economic evaluation of particular services and interventions are reviewed. The resulting eLU-CT datasets were visualized with the MIP technique and yielded virtual radiographs that could be compared with the antemortem radiographs. This study demonstrates that counselling provided to the elderly by a clinical pharmacist significantly improved knowledge about medication and, therefore, the opportunity for compliance at home.

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The possible significance of the observed one-hit process of inactivation has been discussed in terms of the kinetics and the rupture of model substances including nucleic acid. Expression of the Rab4 dominant negative mutant (Rab4AS22N) leads to a significant reduction in both recycling and degradation while, as expected, Rab7 mutants exclusively affect epidermal growth factor (EGF) and low density lipoprotein degradation.

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We presented two cases of falsely elevated CK-MB due to the presence of a type 2 macro CK, showed by isoenzymes electrophoresis. Radioimmunological demonstration of morphine in hematoma blood in a day-and-half survived accident The 2935 cm-1 shoulder, assigned to the acyl chain methyl group C-H symmetric stretching vibration, is difficult to distinguish as a separate spectral transition in the chain disordered state. The efficacy and toxicity of adenovirus-mediated transduction of herpes simplex virus thymidine kinase gene started by Rous sarcoma virus (ADV/RSV-tk) followed by administration of ganciclovir (GCV) were studied in vivo.

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Incubation of granulosa cells with (Bu)2cGMP (2 mM) significantly decreased FSH-induced estrogen levels in a dose-dependent manner (0.25-2 mM). On the one hand, we strive for simplicity, predictability, and operational protection as it is well recognized that software with these attributes will attract an audience of satisfied users.

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Among the Xq27-q28 marker loci used, DXS52, DXS15, and F8C gave the highest combined lod scores, of 14.64, 6.53 and 6.33, respectively, at recombination fractions of .04, 0, and .05, respectively. Time course of the active state in relation to muscle length and movement: a comparative study on skeletal muscle and myocardium. The hygiene theory harnessing helminths and their ova to treat autoimmunity.

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Expression of recombinant human acid sphingomyelinase in insect Sf21 cells: purification, processing and enzymatic characterization. The proposed method can distinguish between highly collinear straight line segments. Extracorporeal portal vein arterialization in man after extended hepatectomy to prevent acute liver failure: a case report. Rice straw was burned in the air to obtain rice carbon (RC), and then the removal of Cr(VI) by RC was investigated under various pHs and ionic strengths. Blood pressure control in a low-income, minority population can be improved by teaching patients to monitor their blood pressure at home and having nonprofessional health coaches assist patients, in particular, by counseling them on medication adherence.

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Sertraline-induced akathisia and dystonia misinterpreted as a panic attack. Luciferase gene-expression assays showed that the TNF- gene promoter contained target sequences for HBx trans-activation within the proximal region of the promoter. This condition was erroneously interpreted as an acute myocardial infarction. The cyclin T1 (Cyc T1) protein has been recently identified, associated with the cyclin-dependent kinase 9 (CDK 9), as to be involved in the transcriptional activation of the Human Immunodeficiency Virus type 1 (HIV-1) by the Tat protein.

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12-step participation and outcomes over 7 years among adolescent substance use patients with and without psychiatric comorbidity. Twenty-three out of 25 subjects sustained clinical improvement in the appearance of acne scarring at the 3-month follow-up visits according to study investigator quartile improvement scoring. A novel method for sex estimation using 3D computed tomography models of tooth roots: A volumetric analysis.

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Although the mechanism of lysenin-induced hemolysis is unique, its precise mechanism of action and its inhibitors are poorly understood. Femoral arterial puncture was performed for blood pressure monitoring during the procedure. Further, we show that the stress-induced antiferromagnetic Mott insulating phase is critical in controlling the spatial extent and distribution of the insulating monoclinic and metallic rutile phases as well as the electrical characteristics of the Mott transition.

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In addition to an introduction to this model, the paper presents a parameter recovery study using simulated data and an application to real data from the field test for TOEFL Internet-based testing. Should all primary care physicians be educated in ultrasonography? By being sessile, plants have evolved a remarkable capacity to perceive and respond to changes in environmental conditions throughout their life cycle.

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A Prospective Study of 7-Year Experience Using Percutaneous 14-French Pigtail Catheters for Traumatic Hemothorax/Hemopneumothorax at a Level-1 Trauma Center: Size Still Does Not Matter. Metabolic changes in the myocardium under the conditions of experimental ventricular fibrillation during extracorporeal circulation in the dog

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Lipid peroxidation in relation to ageing and the role of endogenous aldehydes in diabetes and other age-related diseases. Endocervical columnar cells were found to express keratins 7, 8, 18 and 19, whereas the reserve cells expressed keratins 7, 8, 14, 17, 18 and 19. The PERE contains a sequence homologous to an activating transcription factor (ATF) motif, and ATF-1 is a major component of PERE-protein complexes.

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Ultrastructure and sites of nerve fibers and their endings in epithelial tissue If the latter is true, the causal relationship may be based upon: 1) a submicroscopic chromosomal loss, 2) position effect, or 3) a mutation at the site of the break in one or both translocated chromosomes. Acquired atrial septal defect as a complication of endocarditis--a case report.

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