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The recent progresses in molecular biology and pharmacology approaches allowed the characterization of a series of nuclear receptors (NRs) as efficient regulators of uridine diphosphate glucuronosyltransferase (UGT) genes activity. Pseudoangiomatous stromal hyperplasia of the breast in pediatric patients: an underrecognized entity. The simultaneous occurrence of A 2 -Hong Kong and B strains in an outbreak of influenza in a kibbutz.

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Relationship between extracellular osmolarity, NaCl concentration and cell volume in rat glioma cells. Observation of roton density of states in two-dimensional Landau-level excitations. Our preference, however, because of technical simplicity, is the carotid-axillary bypass procedure. The purpose of the present study was to determine whether ANP, as egg-derived peptides from sea urchins, can act as a chemoattractant to human spermatozoa.

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Determination of the minimum alveolar concentration for halothane, isoflurane and sevoflurane in the gerbil. This case documents that resection may not be necessary to effect cure of abdominal actinomycosis. Neuromodulatory effect of propentofylline on rat brain under acute and long-term hypoperfusion. Note that the expression vector pRF constructed in our study can be not only used to construct multiple copies of the expression cassette in vitro, but also integrated into the P.

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Although papillary meningiomas were considered in our initial differential diagnosis, the final conclusion was possible only when the ultrastructural features were revealed. Dissolution and partitioning behavior of hydrophobic ion-paired compounds.

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The results of this study indicated that adenosine triphosphate in pulp tissues may stimulate a subpopulation of non-substance P trigeminal afferent fibers through activation of P2X3 receptors. The impact of an educational program on recognition, treatment and report of child abuse. Ten patients scheduled to receive intensive chemotherapy were plateletapheresed and the platelet-rich plasma was frozen with 5 percent dimethyl sulfoxide at -80 to -95 degrees C until needed. Genetic autocorrelation was responsible for statistical significance of the genotype-by-environment interaction and genotype main effects on raw data.

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To explore the relationship between syndromes of traditional Chinese medicine (TCM) and genetic background in patients with beta-thalassemia. Some of the phenolic compounds detected in the soil of commercially cultivated American ginseng could inhibit the seed germination and seedling growth of American ginseng. Hairy cell leukemia: a successful model for experimental therapeutics--pentostatin and new ideas.

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A loss of calbindin immunoreactivity in granule cells of the hippocampal dentate gyrus is a characteristic feature of temporal lobe epilepsy with hippocampal sclerosis. Differential patterns of brain activation over time in adolescents with and without attention deficit hyperactivity disorder (ADHD) during performance of a sustained attention task. The expression levels of genes associated with glycolysis, c-MYC, GLUT1, LDHA, HIF1A and pyruvate dehydrogenase kinase-1 (PDK1) were determined by real-time PCR. The nonspecific hypothesis of therapeutic effectiveness: a current assessment.

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We report on three cases of deformation and back out of the Bio-Transfix implant over the lateral, distal femoral cortex, with failure of the passing wire when advancing the graft into the femoral tunnel in one of these patients. We present a model for bone marrow dynamics, which retrieves its ability to continuously modulate the balance between self-renewal and differentiation, even under periodic cytodestructive perturbations. In the intervention region, Amersfoort, there were 82 practices (118 GPs, 250,000 patients) and in the control region, Arnhem, 97 practices (124 GPs, 300,000 patients). To test the usefulness of the fetal transverse cerebellar diameter/abdominal circumference (TCD/AC) ratio in predicting known small-for-gestational-age (SGA) infants. Neither atropine nor indomethacin abolished sham feeding-induced duodenal alkaline secretion.

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Over the last decades hospital at home (HaH) programmes have been set up in many, mainly European, countries. Where it is possible to ascertain a number of families each having two or more siblings with a particular disease, data from such families can be used to test for the presence or otherwise of important genes in the HLA chromosomal region causing susceptibility to the disease.

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The expression of RXR was localized in the epithelial nuclei throughout the menstrual cycle. Open simple prostatectomy is the most effective and the most durable method of controlling symptoms associated with benign prostatic hyperplasia, especially in sub- Saharan Africa, where TURP set and expertise are unavailable in most health institutions.

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Acute lymphoblastic leukemia is the most common malignancy in childhood. Although surgical excision of NMSC remains the standard of care, observation or nonsurgical treatment may be acceptable in many cases of incompletely excised low-risk or minimally transected NMSCs. The purpose of this study was to investigate the effect of pharmacological treatment on asymmetrical dimethylarginine (ADMA) plasma levels in patients with acute congestive heart failure (HF). Finally, an overview of current clinical trials and registries in Germany is presented. Increased population longevity as well as an emphasis on earlier diagnosis and more effective treatment of cancer have created an environment for new technologies and techniques to flourish.

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A wide number of chiral selectors have been employed in CE and among them macrocyclic antibiotics exhibited excellent enantioselective properties toward plenteous racemic drugs. Tissue activator of the fibrinolytic system in placental tissue. Further comparative analysis of mutational hot-spot frequencies and haplotype diversity between the two zones allows determination of whether the External zone haplotypes emerged under positive selection. Protective effect of nitric oxide on development of acute pancreatitis in rats.

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We report the case of a 33 year-old man who was admitted with chronic demyelinating sensorimotor polyneuropathy. Therefore, a challenge has been to disentangle timekeeping from other processes. The results presented in this chapter indicate that the microfluidic IHC protocol developed can provide the possibility of tailored cancer treatments as well as precise histopathological diagnosis using numerous specific biomarkers.

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The search for information is facilitated by the knowledge of the standardized terms commonly used to describe the desired information. To investigate factors related to cardiorespiratory fitness in older human immunodeficiency virus (HIV)-infected patients and to explore the utility of 6-minute walk distance (6-MWD) in measuring fitness.

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However, from human skin impedance measurements, the beneficial effects were not sustained. Evaluation of elevated dietary corn fiber from corn germ meal in growing female pigs. We conclude that Bla g 1 is detectable at potentially significant concentrations in some inner city schools. The cause of posttransplantation hyperlipidemia is not well defined, but obesity and the immunosuppressive agents prednisone and cyclosporine play a role. A new bisphosphonate, YM529 induces apoptosis in HL60 cells by decreasing phosphorylation of single survival signal ERK.

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To study the feasibility, morbidity and outcome of cervical cancer patients treated with laparoscopic assisted radical vaginal hysterectomy (LARVH). The protein is strongly expressed in normal prostatic epithelial glands, but its expression in benign prostatic lesions has not been reported. This approach could be easily extended to conjugate other functional regents if necessary.

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Efficient siRNA Delivery by Lipid Nanoparticles Modified with a Nonstandard Macrocyclic Peptide for EpCAM-Targeting. TA induced higher FeFV production from the Coleman strain carrier culture and also induced marked syncytium formation.

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Biotransformation of D-methionine into L-methionine in the cascade of four enzymes. The aims were to describe the patterns of treatment in a population-based cohort of patients, and compare utilization of RT and chemotherapy to model estimates of need.

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The stronger humoral responses in mice were probably in the first place the result of the relatively higher dosages applied. Microcosm assays and Taguchi experimental design for treatment of oil sludge containing high concentration of hydrocarbons. This is the first case report directly linking rhabdomyolysis with keyboard overuse.

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Results of two levels of adjunctive treatment used with the nicotine patch. Changes in the profile of fatty acids during the metabolic syndrome results from the elevated lipogenesis and from the higher level of oxidative stress. This review summarizes the recently reported MC proliferation inhibitors with their pharmacological properties on the basis of their chemical structures.

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Previous studies have suggested that reprogramming efficiency can be enhanced and that reprogramming kinetics can be accelerated by manipulating epigenetic status. We describe an autopsy case of a patient with NMO and symptomatic involvement of the brain.

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Endoluminal esophageal stent placement is an effective method for the treatment of acute, iatrogenic perforations of the intrathoracic esophagus. A previous study of a recovery-oriented assertive community treatment initiative (PACT) in Washington State found reductions in state psychiatric hospital use and related costs for PACT participants, especially in the first six months after enrollment and for consumers who were high users of the state psychiatric hospital before ACT enrollment. Minimal change renal disease was observed in the first patient whose nephrotic syndrome was steroid resistant.

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A 135kDa DNA polymerase alpha lacking primase activity has been purified to near homogeneity from Coprinus meiotic tissues. We report a 90-year-old man who complained of a thigh abscess that was found to be secondary to a vesicocutaneous fistula. Comparison of different serum-free media for ex vivo expansion of HPCs from cord blood using thrombopoietin, Flt-3 ligand, IL-6, and IL-11. A synthetic gene for the most toxic of the Anthopleura toxins, anthopleurin B (ApB), has been designed, synthesized, and expressed as a fusion protein with the gene 9 product of bacteriophage T7 in Escherichia coli.

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The analysis of pulsatility of pulmonary artery pressure is useful in the differential diagnosis of CPTE and PPH. DPSC and EMSC cultured with TGC as the tooth germ microenvironment can be induced to differentiate into odontoblast.

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A significant reduction in Flk1-GR interaction was observed following CORT exposure. While most of the previously reported CE-MS experiments were performed using capillary electrophoresis in zone format, we report for the first time CE-MS experiments in which CE was performed in frontal analysis (FACE-MS). We hypothesized that nitric oxide exerts a negative feedback control on protein kinase C (PKC) activation, and the disturbance of the feedback control after subarachnoid hemorrhage results in vasospasm due to PKC activation.

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Dissecting cooperative calmodulin binding to CaM kinase II: a detailed stochastic model. Cyproconazole, a triazole fungicide, causes hepatocellular adenomas and carcinomas in CD-1 mice at dose levels of 100 and 200 ppm. Parallel, concurrent surveys were developed for patients and physicians. The social effects in adult life of chronic physical illness since childhood. Five criteria which showed high specificity were selected as follows.

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In this paper, we discuss a novel scoring scheme for sequence alignments. Additionally, we provide insight on the cooperative transcriptional regulation necessary to promote and organize an intricate axonal tree. Hyperspectral analysis using the correlation between image and reference. Cell release was not affected by initial cell density within the beads or by alginate concentration, although higher acidification rates were achieved with increased cell loading. In conclusion, in an experimental metastasis assay, the number of tumors found in bone (after intracardiac injection) and lung (after left femoral vein injection) was significantly reduced in osteopontin-deficient mice compared with wild-type mice.

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Further, a higher cortisol level appears to have a detrimental effect on cognitive performance for individuals with GAD, but not psychiatrically healthy comparison participants. This gap can be reduced by improved glaucoma diagnosis activities in primary care, but there is little empirical evidence regarding use of tonometry in rural settings, or the expertise associated with quality of eye care.

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The PCR products from 7 sarcoid-affected horses were sequenced to evaluate percentage homology with expected sequences for BPV-1 or-2. Investigation into the stability and culturability of Chinese enterotypes. Her metabolism was kept stable throughout the intraoperative period. In the latter case the picosatellite does not have a laser transmitter and the data carrier is the retroreflected beam from the master satellite. NF-kappaB activation was successfully monitored in real time in endothelial cells in response to tumor angiogenic signaling, as well as in monocytes in response to inflammation.

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Assessment of quality of life was done using the Modified Rankin Scale for Quality of Life. Further study of the efficacy of treatment techniques is needed to develop congruous standards for CPT after a burn injury. In mucinous NE carcinomas such granules were less apparent, and the cytological features could have been mistaken for those of fibroadenomas, as in the case of non-NE mucinous carcinomas. We recently reported the production of a species-specific monoclonal antibody (MAb) 6E52D9 immunoglobulin G2a (IgG2a) raised against the exospore of E. Behavioral testing revealed that both cell lines reduced the deficit associated with cerebral ischemia and reduced the infarct volume relative to controls.

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However, there has been no systematic investigation of which factors affect whether people regard themselves as having a family history of CHDor not. HCV RNA was eliminated in three patients of group A and in two of group B patients during 6 months follow up and ALT reverted to normal levels.

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It is proposed that the more on talks to oneself to construct a self-image, the more this image will gain coherence and sophistication. A retrospective hospital record-based study of all children and adolescents with T1DM who were screened for CD was conducted at the Pediatric Diabetes Clinic of King Abdulaziz University Hospital, Jeddah, Kingdom of Saudi Arabia (KSA) between October 2002 and June 2011. The sample size provided adequate statistical power to detect large but not medium or small within-group effects.

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Six patients were identified who had a splenectomy performed for recurrent epithelial ovarian cancer confined to the splenic parenchyma. DOX could be detected by HPLC in the aqueous humor up to 48 h following single subconjunctival injection.

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Phospholipase C-gamma1 (PLC-gamma1), which generates two second messengers, namely, inositol-1, 4, 5-trisphosphate and diacylglycerol, is implicated in growth factor-mediated chemotaxis. Developmental toxicity data were compiled from two sources (the Teratogen Information System and Food and Drug Administration guidelines) and analyzed to identify structural determinants (biophores) associated with human developmental toxicity. Characterization of triple-layered PLGA (shell)/PLLA (middle layer)/EVA (core) microparticles was conducted and their formation mechanism was described. Failure to fertilize in vitro in couples with male factor infertility: what next?

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To describe a model predicting endothelial cell (EC) loss after iris-fixated phakic intraocular lens (pIOL) implantation, taking distance from the edge of the pIOL to the endothelium into account. This work provides original insight suggesting that A-SAA is a player in the dialogue between hypertrophied adipocytes and macrophages through its regulation of adipocyte cholesterol efflux. Data mining is to extract the interested information or knowledge from large databases using a series of techniques. We tested reliability and accuracy of facial measurements by using 30 control subjects and 3 independent examiners. Other indications were multinodular goiter, anastomotic stricture, endobronchial posttuberculosis scar, damaged cartilage and relapsing polychondritis.

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We analysed demographic, perinatal and operative variables as predictors of cognitive outcomes. Members of the freshwater stingray family Potamotrygonidae occur throughout the major river systems of eastern South America that empty into the Atlantic Ocean. Self-mode-locked chromium-doped forsterite laser generates 50-fs pulses. Although some addressed stroke rehabilitation interventions in layperson language, none discussed the numerous treatment options based on scientifically based information. The antifungal activity of allicin was stronger on SG agar medium with a pH of 5.6 than on the same medium with a pH of 6.0 or higher.