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Acute effect of sulphur dioxide on the rate of ciliary beat in the trachea of rabbit, in vivo and in vitro, with studies on the absorptional capacity of the nasal cavity. The incidence of adenocarcinoma of the esophagus is increasing, but the optimal treatment for this disease is unknown. Prevention estimates were calculated through simple mathematical modeling, with values of model parameters determined from published literature. Late hemodynamic changes following controlled hemorrhage and volume restitution with blood or Haemaccel in anesthetized portal hypertensive rats. Information on motor, language and memory functioning is obtained in respectively 13/15, 9/13, and 5/11 children.

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Despite nearly two decades of research, the successful application of systemically delivered non-viral gene therapies to treat human disease is still limited by poor transfection efficiency. Characteristic properties of images of different file formats were measured on Siemens OptiVue500aSi, Siemens BeamView Plus, Elekta iView, and Varian PortalVision and analyzed with the epidSoft 2.0 program in four radiation therapy centers.

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NTHi infection decreased E-cadherin mRNA and protein-levels in lung epithelial cells. The results indicate that mefloquine effectively blocks gap junctions without producing major side effects in vascular endothelial cells and that this compound is a useful tool in the investigation of gap junctions. Recombinant human topoisomerase II alpha and beta induced DNA breakage which was promoted by a variety of agents.

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These data suggest that PTH blocks entry of cells into S phase and inhibits cell proliferation as the consequence of an increase in p27Kip1, which is mediated through the protein kinase A pathway. The effect of naloxone on cortisol and ACTH was stimulatory, while it did not influence prolactin, GH and TSH levels. Systemic corticosteroids are able to control granulomatous reactions, which manifest in the form of outbreaks and tend to undergo spontaneous remission over the years. Expression profiling combined with pathway analysis revealed that PTEN-dependent G1 growth arrest was associated with an altered mRNA expression of the G1 cell-cycle regulators Cdc25a, E2F2, cyclin G2, and RBL2/p130. The subject selection and clustering methods were successful in revealing a set of 9 profile types characterized by unique profile shapes.

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Dopamine (DA) content in the brainstem and hypothalamus was also higher in SHR, but NE and epinephrine (EPI) content in these areas were not different between strains. Effect of neostigmine on concentration and extraction fraction of acetylcholine using quantitative microdialysis. Rats were subjected to 6h RSD starting either immediately after reactivation or 6h later. TB cocoon is a rare form of TB peritonitis presenting usually in the form of bowel obstruction. Increase in protein kinase C activity is associated with human fibroblast growth inhibition.

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Kainate-treated animals did not show areas of neuronal death at the different times following administration considered. However, there is still some disagreement as to the gonadal influence on RES. trkA interacts preferably with nerve growth factor (NGF), trkB with brain-derived neurotrophic factor (BDNF) and neurotrophin-4/5 (NT-4/5) and trkC with neurotrophin-3 (NT-3). How work environment metrics can improve health-care performance. They were often suppressed when the patients were excited or strained.

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Furthermore, inflammation was found to stimulate the expression of PCSK9 in various cells. This study integrated data from 4 clinical trials to determine whether the fluoroquinolone levofloxacin is an effective therapeutic agent for community-acquired pneumonia (CAP) caused by macrolide-resistant S.

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Throughout the manuscript, we use the term economics to refer to classical economics and utility maximization rather than behavioral economics. Neonatal rat cardiomyocytes--a model for the study of morphological, biochemical and electrophysiological characteristics of the heart. The formation of the myelin sheath is a crucial step during development because it enables fast and efficient propagation of signals within the limited space of the mammalian central nervous system (CNS). Within the channel, the Poisson-Nernst-Planck equation is solved analytically in a one-dimensional approximation.

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Medical and phoniatric surveillance of actors and singers in France Comparisons of DSM-IV disorder prevalence estimates among household versus school sample respondents in counties that differed in the use of replacement schools for originally selected schools that refused to participate showed that the use of replacement schools did not introduce bias into prevalence estimates. Our results support the involvement of specific ACE variants in DN pathogenesis and demonstrate the presence of DN-specific haplotypes at the ACE locus.

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It can also result in complex treatment regimens, in which coordination between health care workers is essential. Microradiographic study of bone and dental lesions in fluorine poisoning (3) Current patients were more likely to present at an earlier stage, undergo curative resections, and have improved 5-year survival than institutional historical comparisons. In another case a 44-year-old woman was admitted with 1-month history of headaches, poor memory, imbalance and diplopia. The aim of this study was to determine the risk factors for BMLs in healthy subjects and the association of BMLs with knee structure.

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Instead, we find Exiliboa and Ungaliophis to be most closely related to sand boas (Erycinae), boas (Boinae), and advanced snakes (Caenophidea), whereas Tropidophis and Trachyboa form an independent clade that separated relatively early in snake radiation. Hyaluronan is the most abundant glycosaminoglycan of the extracellular matrix and is a critical substrate for cellular attachment and locomotion. ducreyi isolates do not exhibit cytotoxic effects on the epithelial cells of the skin.(ABSTRACT TRUNCATED AT 400 WORDS) Within individual IDC specimens, the stromal cells or morphologically normal epithelium revealed low labeling that was always significantly less than the labeling of neoplastic cells.

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Transduction of the neonatal brain has been accomplished by a variety of methods, including direct intraparenchymal injection, intraventricular infusion, and intravenous administration. However, occupational information was limited and risk estimates for women in specific occupations were imprecise.

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Traumatic herniation of buccal fat pad in a case of twenty-month-old girl is presented. Concerning bone metabolism, in vitro studies have shown that oxidative stress inhibits osteoblastic differentiation and induces osteoblast insults and apoptosis.

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Over the past decade, the assessment of the disease activity in psoriatic arthritis (PsA) has rapidly evolved in view of the need for valid, feasible, and reliable outcome measures that can be ideally employed in longitudinal cohorts, clinical trials, and clinical practice as well as the growing paradigm of tight disease control and treating to target in the management of PsA. SP-C and SP-B were labeled with the fluorescent probe, succinimidyl nitrobenzoxadiazolyl amino hexanoate (NBD).

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While the presence of an AXA motif at the cleavage sites was readily apparent, it was the presence of a glutamine residue adjacent to the cleavage site that may affect secretion efficiency. This fragment can bind to LH/hCG receptor cDNA in Southern blotting. Thrombosed primary cervical esophageal varices causing acute respiratory distress. Hospitalist-orthopedic co-management of high-risk patients undergoing lower extremity reconstruction surgery. Porcine skin-derived stem cells can serve as donor cells for nuclear transfer.

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Contrast-enhanced CT scans were obtained at 8- to 12-week intervals on 31 consecutive patients with primary or metastatic hepatic malignant tumors. During the dissections of 50 adult cadavers for educational purposes, we found a 45-year-old male cadaver with an abnormally coursing facial vein which has joined the retromandibular vein at a higher level--in the parotid gland--on the right side of the face. In addition, the ratio of mRNA expression in the mammary glands of adult females relative to adult males is significantly greater for Brca1 than for Brca2.

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We examined the hypothesis that supplementation of nitric oxide (NO) with the novel NO donor, S-nitroso-human-serum-albumin (S-NO-HSA), may reduce iNOS expression, lung inflammation and acute lung injury in a rat model of septic shock. These pathways have been proposed to act independently but their respective contributions and mode of interaction have remained elusive. Both patients, during evaluation for recurrent abdominal pain, underwent endoscopic retrograde cholangiopancreatography that revealed typical changes of chronic pancreatitis and pseudocysts confined to 1 ductal system with the other ductal system completely normal. We assessed human telomerase activity, protein and gene expression for the telomerase reverse transcriptase, as well as expression of the telomeric template RNA hTER in hepatic stem cells and in various developmental stages of the liver from fetal to adult.

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In prior work on computer simulations of the competition between on-pathway folding and off-pathway aggregate formation, we found that long sequences of consecutive hydrophobic residues promoted aggregation within the model, even controlling for overall hydrophobic content. The first case with symptoms fully related to kidney and the second mimicking epididymorchitis hindered prompt diagnosis. Furthermore, its pathway regulates mechanisms which involve plasmin and matrix metallo-proteinases, both of which seem to be critical in oral carcinogenesis.

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These data demonstrate that local-regional control with electron are therapy of the postmastectomy chest wall is comparable to photon techniques. Nevertheless, several lines of research raise the hope of generic treatments applicable to all such patients, while the greater understanding of normal visual function that arises from genetic studies may open up new avenues for therapy. tweek mutants show reduced FM1-43 uptake, cannot maintain release during intense stimulation, and harbor larger than normal synaptic vesicles, implicating it in vesicle recycling at the synapse. An increased incidence of haemangiomas in infants born following chorionic villus sampling (CVS). Simple and sensitive colorimetric detection of cysteine based on ssDNA-stabilized gold nanoparticles.

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Results showed that, in contrast to mice, the CD4 protein on human vaginal and peripheral blood T lymphocytes are similar at both the molecular and protein levels. One of the most stimulating problems posed by second generation antipsychotics is the question of whether their ability to act on the negative, as well as the positive, symptoms of schizophrenia relies on the same neurochemical mechanisms as those responsible for their lack of extrapyramidal symptoms (EPS). Periodic density functional theory and local-MP2 study of the librational modes of Ice XI. Plasma protein variations in hemophiliacs receiving factor replacement therapy. All had initial cytoreductive surgery for Stage III disease followed by platinum-based chemotherapy.

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The protease domain of EBV was expressed in Escherichia coli and its structure was solved by X-ray crystallography to 2.3A resolution after inhibition with diisopropyl-fluorophosphate (DFP). C-arm based surgical navigation system is a kind of computer assisted surgery (CAS) system. Indeed, none of the above properties has never been clearly demonstrated even for the ruthenium drugs that entered clinical trials.

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Organization and functioning of services for old chronic mental patients Influenza vaccine might prevent severe influenza in these risk groups. These arterial changes resulted in transformation of the cerebral arteries, in particular almost all the medullary arteries, to a so-called earthen pipe state.

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Type 1 fimbriae, a colonization factor of uropathogenic Escherichia coli, are controlled by the metabolic sensor CRP-cAMP. A Constant-Volume Ventilator and Gas Recapture System for Hyperpolarized Gas MRI of Mouse and Rat Lungs.

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Experiment 1 revealed that this tendency was reduced when individual or group participants interacted with individual or group confederates who followed a tit-for-tat strategy as opposed to a Pavlov strategy or a standard control condition that did not involve confederates. We studied perceptual learning by determining psychophysical discrimination thresholds for visual hyper acuity targets (vernier stimuli) as a function of stimulus orientation. A significant correlation appears to exist between RV-to-LV conduction time and the improvement in systolic function with CRT.

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Medical-dental findings and management of a child with infantile Refsum disease: a case report. Further research concerning the mandibular model in minipigs is required and more refinement needed to assure a standardized CSD, allowing qualitative and quantitative evaluation of bone grafts and bone graft substitutes.

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Patients with monoclonal gammopathies of uncertain significance (MGUS) may develop an acquired bleeding disorder similar to congenital von Willebrand disease, called acquired von Willebrand syndrome (AvWS). Herpes simplex virus type 2 seroprevalence data may be used as a marker of past sexual behavior for the direct comparison of different population groups. The ESR properties, DNA nicking, and DNA association of aged solutions of catechol versus aqueous extracts of tar from cigarette smoke. It has also been shown that breast feeding delays the onset of the disease. Understanding the anatomical and functional organization of the temporal pole enables us to hypothesize about the role played by this structure in the pathogenesis of the forms of epilepsy originating in mesial temporal lobe structures.

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Until results from such a prospective trial are available, COBPM is the method of choice for evaluation and management of hypertensives. The differential expression of ribosomal protein (RP) L7, RPL7 pseudogene (RPL7p), RPL19 and tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta polypeptide (YWHAZ) were further confirmed by RT-PCR. A patient with transient ischaemic attacks due to fibromuscular dysplasia of the internal carotid artery is presented. Activity-dependent SUMOylation of the brain-specific scaffolding protein GISP.

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Linked responses to mechanical dilatation could only be obtained with very rapid stretching stimuli or high amplitudes of distension of the vessel. Here, we investigate the level of polymorphism and the evolution of sequences that code for the peptide-binding regions of MHC class I and class II DRB genes in the Alpine marmot (Marmota marmota). The clinical, pathologic, and radiographic features of giant cell tumors are discussed.

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We performed microarray studies using HEK 293T cells and discovered that Chmp1A positively regulated Cellular retinol-binding protein 1 (CRBP-1). Chemically patterned microspheres for controlled nanoparticle assembly in the construction of SERS hot spots. All patients were checked for a prior history of stroke, and the risk factors for stroke and atherosclerosis were evaluated. The aim of this study is to evaluate the exercise, anthropometric, and blood parameters in lean, sedentary patients with OSA compared with controls.

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The computed second harmonic generation (SHG) from a slab of a nonlinear material is then compared with the analytical model. Generalized tonic-clonic status epilepticus: causes, treatment, complications and predictors of case fatality. Polycapillary-optics-based micro-XANES and micro-EXAFS at a third-generation bending-magnet beamline.

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The renal cortex has an unusually high rate of palmitic acid utilization. This may be due in part to the difficulties in distinguishing these organisms from other genera such as Actinomyces. In contrast, bilateral spinal increase of OX-42 immunoreactivity indicative of microglial activation began at 4h peaked at day 1 and gradually reversed by days 3 to 7 after the administration of BmK venom.

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In infants with severe congestive heart failure, earlier correction should be contemplated, although it carries a higher morbidity. A model of time-delay recurrently coupled spatially segregated neural assemblies is here proposed. Methotrexate (Mtx) is accepted modality for conservative treatment of ectopic pregnancy. The reference population for comparison of LDU was the Swedish from 1984. Bcl-2 was not up-regulated in both B cells stimulated with LPS plus IL-21 and IL-4.

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Consequently, it has been adopted by many organizations recently, and the initial results are very promising. At fixed volume fraction, the barrier grows in a parabolic manner with inverse temperature nondimensionalized by an onset value, analogous to what has been established for thermal glass-forming liquids.

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This chapter introduces the various techniques to asses the function of CFTR. The most likely origin of premature ventricular contractions (PVCs) may be deduced from surface electrocardiogram (ECG) analysis while planning an electrophysiological study (EPS).

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Tuberculosis in health professionals: a new perspective on an old problem. According to our tentative definition, all of these disorders should be collectively called microangiopathy. Probing osmolyte participation in the unfolding transition state of a protein. The depth of the nanopatterns is magnified after development, and is varied by exposing dosage and line width of the pattern.

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We combine density functional theory (DFT) with molecular dynamics simulations based on an accurate atomistic force field to calculate the pressure derivative of the melting temperature of magnesium oxide at ambient pressure--a quantity for which a serious disagreement between theory and experiment has existed for almost 15 years. All the patients included in the study were subjected to blood tests. We have shown that hundreds of genes change their expression in the porcine skeletal muscle in response to nutrient intake. The device life of Provox and that of Provox 2 were comparable, despite the alterations needed to optimize the Provox 2 prosthesis for the anterograde procedure. Anesthetic management of toxic epidermal necrolysis: report of three adult cases.

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Lower posterior mediastinal paraspinal tumors can be resected laparoscopically with careful preoperative investigation for tumor localization and a meticulous laparoscopic technique. L-asparagine requirement and the effect of L-asparaginase on the normal and leukemic human bone marrow. Considering graphs with fixed in-degree, we characterize analytically and numerically the feedback regions using graph decimation algorithms (Leaf Removal). The intracranial part was removed by cutting a small window in the frontal bone directly over the dermoid, minimizing complications of formal craniotomy.