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Brain atrophy, and in particular the characteristically-enlarged Sylvian fissures, was better demonstrated by MRI. The integration assay employs a novel quantitative form of Alu-PCR that should be generally applicable to studies of integrating viruses and gene transfer vectors. Although p53 protein overexpression is commonly observed in adenocarcinoma of the esophagus, its prognostic value appears limited.

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This study evaluates whether the early use of PADT affects the subsequent receipt of additional palliative cancer treatments such as chemotherapy, palliative radiation therapy, or intervention for spinal cord compression or bladder outlet obstruction. This paper reviews the findings of investigations in which a transgenic mouse has been assessed for nociceptive or analgesic sensitivity.

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Given the clinical impact of molecular diagnostics in rarer monogenic forms of these diseases, expectations have been high that genetic discoveries will transform the prospects for risk stratification, development of novel therapeutics and personalised medicine. Molecular adjuvants are a promising method to enhance virus-specific immune responses and protect against HIV-1 infection.

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There was a 3-fold increase in the apparent Km value on immobilization. Gestation duration, number and weight of newborns, and fertility and gestation rates were recorded. A reassessment of the function of floral nectar in Croton suberosus (Euphorbiaceae): A reward for plant defenders and pollinators. Rapid isolation in large numbers of intact, viable, individual hair follicles from skin: biochemical and ultrastructural characterization.

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FTIR, NMR and DSC measurements clearly show the blending and cross-linking between the constituents. Research into the structure of the kidney glomerulus--making it count. Rat pituitary cells were pretreated with CC, then stimulated with GnRH with and without co-administration of different concentrations of GnRH antagonist and compared with non-CC-pretreated controls. This latter regulation requires that safe foods be produced in accordance with Product Safety Programmes approved by the Ministry of Agriculture and Fisheries. Serum samples were treated with dithiothreitol and the protein-freed product was derivatized with 2,4-dinitrofluorobenzene.

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Lamotrigine monotherapy appears to be effective in maintaining symptom control of manic and depressive symptoms in PBD and shows minimal adverse effects, although a future double-blind controlled trial is needed to confirm this finding. The method can be a very useful tool to find where, what, and how contamination has happened. Guatemalan adolescents frequently consume SSB, which may be encouraged by aspects of the school environment. To date, attempts to unravel the complex pathogenesis and pathophysiology of diabetic nephropathy have mostly focused on the glomerulus. The suitability of a material for the creation of thermo-chromatographic pulses depends on its dielectric properties as well as on its sorption properties with respect to water or other coupling media.

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Homocysteine levels are dependent on Marsh classification and the regular use of B-vitamin supplements is effective in reduction of homocysteine levels in patients with celiac disease and should be considered in disease management. A case of asymptomatic primary biliary cirrhosis with granuloma accompanied by giant cell

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Animals were randomized to receive either: citicoline 500 mg/kg or saline IP prior to collagenase and at 24 and 48 hours. The tumor-infiltrating lymphocytes and sarcoid reactions may have been immunological responses to the cancer and may have caused the transient regression. Animal model of PTSD was induced using a mouse single prolonged stress protocol (mSPS). Similarities and differences of the soleus and gastrocnemius H-reflexes during varied body postures, foot positions, and muscle function: multifactor designs for repeated measures.

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In children and adolescents the evaluation of proteinuria is cumbersome because of the need to obtain timed urine collections. Protein phosphatase 2A (PP2A) functions as a potent tumor suppressor, but its mechanism(s) remains enigmatic. A Petri dish bioassay was used to study chemoattraction of the cercariae of Echinostoma trivolvis and E. Behaviour of the iris vasculature in central retinal vein occlusion: a fluorescein angiographic study of the vascular response of the retina and the iris.

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These findings indicate that chimpanzees recovered from typhoid fever may be protected against re-infection, even though the re-infecting organism is of a different phage type. The effect of age and sex was different according to the additive or multiplicative model used, whereas the effect of the first modality of dialysis or the primary nephropathy was similar.

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Comparative effects of secretin (SEC) and cholecystokinin-octapeptide (CCK-8) on pancreatic microcirculation. Nanogyroids incorporating multivalent lipids: enhanced membrane charge density and pore forming ability for gene silencing.

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Recommendations are made to promote ethical integrity in conducting mental health research with adolescents. Human genome mapping using FISH has been significantly enhanced by the development of new techniques, especially high-resolution gene mapping with direct R-banding FISH and physical gene ordering with multi-color FISH.

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The anterior teeth near the cleft area having anomalies and positions of the clefts were also recorded. Reliability and validity of the compliance belief scales among patients with heart failure. We considered 873 consecutive procedures, of which 406 percutaneous coronary interventions (PCI), performed by a single operator (S.R.) who had previously completed the learning curve in TRA at a high volume center. Although knowledge base decreases similarly with time after both courses, the new interactive course participants maintained a consistently higher clinical skill performance level at 2 years. The tetracycline diagnostic test for stomach cancer (in reference to the article by P.

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In this work, the crystal structure of a Lys49-PLA(2) homologue from Bothrops brazili (MTX-II) was solved in two conformational states: (a) native, with Lys49 singly coordinated by the backbone oxygen atom of Val31 and (b) complexed with tetraethylene glycol (TTEG). The risk of fracture calculated by FRAX in the patients sent to a densitometry unit for bone BMD testing seems low and, probably, a better selection of the patients would detect a higher risk of fracture population.

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In this review, we summarize what is known about the specific importance of some of the components of the ECM in relation to the cardiovascular development. Effect of running shoe type on the distribution and magnitude of plantar pressures in individuals with low- or high-arched feet.

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A Pub Med and Medline review of the randomized controlled studies utilizing OTC vitamins and supplements readily available in the United States over the last 3 decades was performed. All patients described a better appearance after application of the product, and none had an allergic response. In diabetic group microvascular permeability and the number of sticking leukocytes to the venular endothelium were increased. A polypeptide encoded by the NTS 16 open reading frame has sequence similarity to the catalytic domain of several receptor protein kinases from plants including the S-receptor kinases implicated in the rejection of self-pollen in Brassica species and the Pto gene product of tomato which confers resistance to a bacterial pathogen. Targeted gene mutations in mice that cause deficiencies in protein glycosylation have revealed functions for specific glycans structures in embryogenesis, immune cell regulation, fertility and cancer progression.

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On September 27-29, 1993, the Study Group on Anorexia Nervosa (AN): Basic Mechanisms, Clinical Approaches and Treatment met in Geneva, Switzerland to discuss recent progress in research on anorexia nervosa, and to identify directions for future studies. The coordinated activity of thousands of cellular oscillators in the suprachiasmatic nuclei (SCN) temporally regulates mammalian physiology to anticipate daily environmental changes across the seasons. Although the staining patterns of these primary tumors have been extensively examined, the utility of these immunohistochemical profiles has not been studied in the context of metastatic lesions to the bone marrow.

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Global regulators and environmental adaptation in Gram-negative pathogens. Vanol is a member of the vaulted biaryl family of ligands and it has been proven to be very effective in a number of asymmetric catalytic reactions. We report here the epitope localization and functional effects of a monoclonal antibody (MA-124K1) that inhibits rat PAI-1 activity and simultaneously increases the binding of inactive PAI-1 to vitronectin (the affinity constant of PAI-1 for vitronectin is 2 x 10(7) m(-1) in the absence of MA-124K1 and 160 x 10(7) m(-1) in the presence of MA-124K1). Scorpion stings presenting to an emergency department in Singapore with special reference to Isometrus maculatus.

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The results of the study highlight the importance of taking several actions by all healthcare workers and by the community to optimise health care provided for elderly people. Intrinsically disordered proteins (IDPs) or proteins with disordered regions (IDRs) do not have a well-defined tertiary structure, but perform a multitude of functions, often relying on their native disorder to achieve the binding flexibility through changing to alternative conformations.

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Remission induction with Poly IC in patients with acute lymphoblastic leukaemia (preliminary results). Gluco- and mineralocorticoid biological effects of a 7-day treatment with low doses of hydrocortisone and fludrocortisone in septic shock. A retrospective study of ADPKD patients was undertaken April-December 2014 in Denmark, Finland, Norway and Sweden. Thrombocytopenic patients with surgically correctable lesions such as radial clubhands are too often repeatedly transfused with randomly pooled platelets. Both underproduction and overproduction of nitric oxide (NO) could lead to various eye diseases.

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Effectiveness of a new calcium antagonist in severe hypertension. The cervical carcinoma was the most frequent primary site (61 cases), followed by the urethra (5 cases), vagina (4 cases), endometrium (3 cases), breast (2 cases), ovary (1 cases), rectum carcinoma (1 cases) and malignant lymphoma (1 cases). Among them the most important are those with free sulphydryl groups (-SH), which can break the disulphide bonds of the bronchial secretions. Forelimb mobility required by gliding occurs at the acromion-clavicle and glenohumeral joints, is different from and convergent to the shoulder mobility at the pivotal clavicle-sternal joint in marsupial and placental gliders. Irritation, depression, lack of concentration, sleep disturbances, anxiety, tension, and restlessness were frequently reported as abstinence symptoms.

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Finally, MUC2 regulation by butyrate at 10-15 mM was associated with increased acetylation of histone H3 and H4 and methylation of H3 at the MUC2 promoter. These exposure levels should protect the surgical staff from adverse neurological, cardiovascular, respiratory, and irritant effects.

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An optimal complex of radiological methods to detect each of these complications has been developed. Low calcium and parathormone levels confirmed the diagnosis of hypoparathyroidism. In the second step, a more detailed evaluation considered twenty criteria based on data quality, applicability, data collection methods, data analysis and interpretation, existing data and programs, and cost effectiveness to select a draft set of core monitoring variables (CMV). Improvement of recipient survival after small size graft liver transplantation in rats with preischemic manipulation or administering antisense against nuclear factor-kappaB. Serum lactate concentration and hepatic enzyme (aspartate aminotransferase, gamma-glutamyl transferase, glutamate dehydrogenase) activities were measured using an automatic analyzer.

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The breakup of annuluses in a core-shell structure in two dimensions is analyzed. Phenotypic and functional differences between human dendritic cells derived in vitro from hematopoietic progenitors and from monocytes/macrophages. Data on socio-demographic, clinical and anthropometric characteristics were collected from 238 hypertensive participants using WHO stepwise technique. Therapeutic Enzymes: Applications and Approaches to Pharmacological Improvement.

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Molecular defect of a phosphoglycerate kinase variant associated with haemolytic anaemia and neurological disorders in a large kindred. Median age at repair was 0.78 years (0.08-0.99) and median follow-up was 3.0 years (0.08-10.4). The results and limitations of this method for diagnosis of diseases of the gallbladder, bile ducts, liver, pancreas, spleen, kidney and urinary tract, adrenal glands, vessels and lymph nodes, female pelvis and gastrointestinal tract are presented in a short overview. Genetic variability among humans and their predisposition towards pathologic inflammatory responses have also been demonstrated. Thrombosis made reconstruction difficult and at times required a femoro-tibial graft.

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Biological reconstruction after resection of bone tumours around the knee: long-term follow-up. In this study we used rat liver epithelial stem-like cells (WB-F344) to examine the effects of cyanobacterial extracts on two established markers of tumor promotion, inhibition of gap-junctional intercellular communication (GJIC) and activation of mitogen-activated protein kinases (MAPKs) - ERK1/2. Studies searching for relevant components of compliance behavior can be divided in two groups. Detection of HPV-DNA by a PCR-based method in formalin-fixed, paraffin-embedded tissue from rare endocervical carcinoma types. Predicting physical properties of emerging compounds with limited physical and chemical data: QSAR model uncertainty and applicability to military munitions.

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Recent advances show that interactions between lipoproteins, coagulation and growth factors are important in atherosclerosis. An 18-year-old male with dyspnea and pulmonary arterial hypertension.

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Nurses are going to be called, increasingly, to act as AIDS counsellors. VSMC migration towards immobilized aggretin was increased in a modified Boyden chamber and this effect was blocked by alpha2beta1-Src-PLC-MAPK axis inhibitors, but not by PDTC, PDGFR-beta mAb, or a phosphoinositide-3 kinase inhibitor, LY294002. The feature of induced cells from hEBs was characterized by flow cytometry, Wright-Giemsa staining, and colony-forming assays.

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Ancylostoma caninum: reduced glutathione stimulates feeding by third-stage infective larvae. We investigated the interrelationships of IL-6 and TNF-alpha, tissue injury, infarct size, cardiac function, and collagen formation in humans. The pathology report indicated primary cardiac lymphoma that was regressed by post-operative chemotherapy.

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Postoperative pain is less and recovery is significantly faster. Assessing the safety of Pseudomonas putida introduction in the environment: an overview of ecotoxicological tests. The slides were then traced on paper after staining with haematoxylin and eosin and the distribution of striated muscle mapped. We suggest that it would be much more cost-effective for all these patients to have an ultrasound scan within 2 weeks instead of a urology clinic appointment. Translating evidence into nursing practice: oral hygiene for care dependent adults.

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Since ephedrine has a thermogenic effect and it is frequently used to treat hypotension during anesthesia, this study was designed to determine the effect of ephedrine on intraoperative hypothermia of patients who are undergoing spine surgery. Construction and characterization of a high activity mutant of human keratinocyte growth factor-2. The findings of this study suggest that there is evidence of inflammation in the airspaces of patients with HPE. Her condition then worsened and she developed signs of recoarctation, with an increased Doppler pressure gradient in the descending aorta.

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Blood-brain barrier disruption and matrix metalloproteinase-9 expression during reperfusion injury: mechanical versus embolic focal ischemia in spontaneously hypertensive rats. Tibial lengthening over an intramedullary nail in patients with short stature or leg-length discrepancy: a comparative study. There was a decrease in tissue hysteresivity (GL/HL) with repeated antenatal steroid exposure.

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Th2 cytokine inhibitor suplatast tosilate inhibits antigen-induced mucus hypersecretion in the nasal epithelium of sensitized rats. To assist with the much-needed suprageneric reclassification and with studies of evolution of chemical compounds and biogeographic history of the family, here we included sequence data (from two noncoding regions of the chloroplast genome-rps16 intron and trnL-trnF region) from 65 species in 59 genera (more than one third of those in the family) that represented all subfamilies and tribes and more genera of Toddalioideae and of neotropical groups than previous studies. The objective of this paper is to demonstrate the importance of a rigorous and comprehensive evaluation of predictive tests in acute leukemia, especially when these may influence therapeutic decisions. Serum aspartate aminotransferase levels were lower in the livers preserved in the Wisconsin solution.

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hiPS cells can differentiate into myocytes with cardiac-specific molecular, structural, and functional properties. 3-T multiparametric MRI characteristics of prostate cancer patients suspicious for biochemical recurrence after primary focal cryosurgery (hemiablation).

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Linear regression analysis of the area/pressure relationship in two consecutive cardiac cycles (systolic phase only) was performed before and during adenosine and norepinephrine infusions. The functional role of seven serines and threonines in the T beta R-I GS domain was investigated by mutational analysis.

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The evaluation for generic-level monophyly of Ancyrocephalinae (Monogenea, Dactylogyridae) using ribosomal DNA sequence data. Peroxisomal assembly defects: clinical, pathologic, and biochemical findings in two patients in a newly identified complementation group. This review provides a critical overview of the most recent literature on the use of gold nanomaterials as non-conventional desorption ionization promoters in LDI-MS, with particular emphasis on bioanalytical applications. The reports on increases in the incidence of other types of cancer are difficult to interpret because of methodological limitations.

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Socio-demographic characteristics, parent-child relationship, peer relationship and relationships in schools were explored as correlates of the psychological wellbeing of children of migrant workers. Because these modes are not well captured in a laboratory environment, understanding on-road relationships is critical in evaluating the emissions reductions that may be possible with biodiesels. Survival data for conventionally detected cases were derived from the Surveillance, Epidemiology and End Results database for men diagnosed in the years 1983-1988. Liquid chromatographic determination of biotin in multivitamin-multimineral tablets.

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Genomic mapping by end-characterized random clones: a mathematical analysis. Transition of the radial electric field by electron cyclotron heating in the CHS heliotron/torsatron. Genetic variants of the human obesity (OB) gene: association with body mass index in young women, psychiatric symptoms, and interaction with the dopamine D2 receptor (DRD2) gene. An exploration of the ability of tepoxalin to ameliorate the degradation of articular cartilage in a canine in vitro model.

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Functional reconstitution of a receptor-activated signal transduction pathway in Xenopus laevis oocytes using the cloned human C5a receptor. Here, we describe a technique that uses electrophoresis of yolk proteins to determine egg ownership, which we applied to communally breeding guira cuckoos (Guira guira). In vivo reduction of bacterial populations in the urinary tract of catheterized sheep by iontophoresis.