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Point mutations in the conserved hexanucleotide motif of the terminal loop caused moderate virus attenuation. Pulmonary artery embolism caused by tumor mass in a case of thyroid carcinoma infiltrating the heart Higher than normal glutamine levels in the left anterior cingulate and thalamus provide in vivo evidence of greater than normal glutamatergic activity proposed by glutamatergic models of schizophrenia.

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Exercise training and blood viscosity in patients with ischemic heart disease. Differential expression of CD14-dependent and independent pathways for chemokine induction regulates neutrophil trafficking in infection. Cardiorespiratory parameters in draught horses before and after short term draught work pulling loads.

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Innovations in both arms of the cerebrovascular field will continue to advance the field and provide novel approaches to these complex lesions. In the studies presented here the diagnostic usefulness of tumor markers in lung cancer was evaluated, using as a reference group workers of a chemical plant producing chromite and chromate pigments. To develop and validate a diagnostic score that assists in discriminating primary hemophagocytic lymphohistiocytosis (pHLH) from macrophage activation syndrome (MAS) related to systemic juvenile idiopathic arthritis. On the basis of data obtained by the methods of hydrophobic chromatography, sedimentation, and differential scanning calorimetry, conformational models of protein-proxanol conjugates were suggested. The psychiatry of toxic exposure and multiple chemical sensitivity.

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A community care initiative: Maryland and Hopkins students take to the streets in Baltimore City. The ratio apo-CRBP1/holo-CRBP1 participates by influencing retinol flux into and out of storage as retinyl esters, thereby modulating substrate to support atRA biosynthesis. Participants were 335 adolescents involved in sport practice, and 435 adolescents not involved in any form of regular sport practice. The origins of SCoV have been mysterious and controversial, until the recent discovery of SARS-like CoV (SLCoV) in bats and the proposal of bats as the natural reservior of the Coronaviridae family. Continuous wound infiltration is an effective postoperative pain control technique with minimal side effects, after spinal surgery.

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In 23 patients with ALTE no dependence of flow in the BA and both VA of head and body position could be shown. The semiautomated AV apparatus dynamic assessment using eSie valve software is a clinically feasible technique and can be performed readily in the operating room. One had a double limiting membrane and content that resembled the surrounding cytoplasm. Remarkable changes in cardiorespiratory interactions are frequently experienced by Chan meditation practitioners following years of practice. The aim of our study was to evaluate the involvement of essential pro- and antisecretory neurotransmitters in regulation of secretion in porcine proximal colon.

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This implies systematic investigation of all cases of chest trauma, even minor, by transthoracic, or preferable, transoesophageal echocardiography, looking for haemopericardium. The unusual case of a patient presenting with gaze-evoked amaurosis as an early and isolated sign of orbital angiomyoma is reported. Directional coronary collateral growth with chronic circumflex occlusion in the dog. A rat model of middle cerebral artery occlusion (MCAO) was established. (On an analysis of the genesis of the state of hypoplasia of the cardiovascular system)

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The enzymes accumulated in the particulate fraction of the medium (brush border membrane fraction) suggesting an increased turnover of membrane components by a process of shedding or microvesiculation. However, the prognostic value of VEGF in patients with prostate cancer remains controversial. Ferrite particles: a superparamagnetic MR contrast agent for the reticuloendothelial system. A zone showing a severe destruction of the regularly fibrillar structure is observed in the centre of each core. rs2241423 was associated with BMI and obesity in two independent European cohorts suggesting a role for MAP2K5 in early weight regulation.

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Hernias and eventration of the diaphragm in infants (clinico-radiological study of 27 cases) Recently, greater progress has been made in the study and use of FTIR in the fields of environmental accident emergent monitoring, environmental monitoring and environmental chemistry research.

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The mechanism of induction of these antibodies still remains obscure. We conclude that the method described here is useful for quantitative estimation of SPEM in clinical neuro-otological examinations. However, open source comprehensive web tools for analysing data obtained from different platforms and technologies are still lacking.

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We prepared with a lysis-squirting protocol basal cell membranes, that are suitable for scanning probe microscopy. It is attempted to associate these processes with some immunomodulating effects of hemoperfusion.

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Taken together, these results indicate that elevated levels of KLK6 in GBM are likely to promote the resistance of tumor cells to cytotoxic agents and are an indicator of reduced patient postsurgical survival times. Determining indications for primary removal of regional lymph drainage vessels in lip cancer

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In situ hybridization localized TNF-alpha mRNA exclusively to glomerular epithelial cells in all biopsies with membranous morphology but not in other histological subtypes. HIV incidence in young girls in KwaZulu-Natal, South Africa--public health imperative for their inclusion in HIV biomedical intervention trials. gondii DNA in blood, and show that circulating DNA is present for long periods in mice following primary infection.

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A microscope automated fluidic system to study bacterial processes in real time. We measured the concentration of neurotransmitters in immortalized neural cell lines of hippocampal, septal, brainstem and cerebellar origin.

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This study presents the biodistribution, safety and absorbed dose of 123I-VIP administered to 18 patients with intestinal adenocarcinomas or endocrine tumors. The average age of the patients at the time of the operation was fourteen years (range, seven years and nine months to seventeen years and eleven months). Evidence for site-sensitive screening of core holes at the Si and Ge (001) surface. The present study investigates the pharmacologically active constituents of rose oil, which possesses anti-conflict effects. The effects are robust and are achieved by varying the strength and duration of a Gaussian pulse, that is, no careful tuning of the pulse shape is required.

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Other factors that might account for seasonal changes in parasitism by gregarines are either unlikely or can be discounted including sampling of older damselflies mid-season but not late in the season, or sex biases in parasitism and overrepresentation of the more parasitized sex mid-season. Laser frequency bandwidth narrowing by photorefractive two-beam coupling. The jetting and the meniscus oscillation behavior are experimentally investigated under ac voltage, ac voltage superimposed on dc voltage, and pulsed dc voltage.

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This paper studies a steady axisymmetric flow in a constricted rigid tube. We observed reduced fractional anisotropy in the demyelinating plaques and in the NASC of MS patients, corroborating the hypothesis that the histological extension of the MS lesions is more severe than the abnormalities seen in the conventional MRI sequences. Over a series of experiments, configurational effects of letter-fragment (LF) and non-letter-fragment (NLF) masks were compared.

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By using a GIF-N30 fiberoptic endoscope and a tiny cup biopsy forceps (1.8 mm diameter), unsedated transnasal endoscopy was performed and antral biopsy specimens were taken for a CLO test, histologic analysis (Dieterle stain), and tissue culture. The purpose of this article is to review the computed tomography (CT) and histopathological features of uncommon primary neoplasms of the thorax that can manifest clinically malignant features (multiplicity of pulmonary nodules, an invasive nature, and metastases or recurrence after surgery) with little evidence of histological malignancy.

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The most important vasodilators are calcium-antagonist and Epoprostenol (prostacyclin PGI2). This release in pressure may result in dimensional changes that distort the denture base. Levels of beta-secretase (BACE1) in cerebrospinal fluid as a predictor of risk in mild cognitive impairment. Cytomegalovirus infection and viral shedding in the genital tract of infertile couples.

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Salycylhydroxamic acid in the treatment of mycosis of the scalp in children Reconstruction with free jejunal graft after total circular pharyngolaryngectomy. Diode laser decreases the activity of catalase on submandibular glands of diabetic rats. Together, our data suggest that PARP1 and PARP2 detect disrupted replication forks and attract Mre11 for end processing that is required for subsequent recombination repair and restart of replication forks.

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18 patients with distinct improvement of mood in the evening and 18 patients without, both suffering from major depression and equally treated with tricyclic antidepressants (TCA), and an age- and sex-matched group of 18 normal control subjects underwent a standardized heart-rate (HR) analysis (HRA) in the morning (08:00) and 12 h later in the evening (20:00). Mesoporous polyaniline-silica nanocomposites with a full interpenetrating structure for pseudocapacitors were synthesized via the vapor phase approach.

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Brain tumor formation and growth is accompanied by the proliferation and infiltration of blood capillaries. Specifically, we sought to determine if absolute insulinopenia was present or whether encainide-induced diabetes was metabolically more like type II than type I diabetes. Fluorinated hydrocarbons as substances for inhalation anesthesia

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Fifty patients with sleep-related breathing disorders were tested with nocturnal polysomnography and with nasendoscopic diurnal polysomnography after diazepam administration, and various indices of breathing disorders were examined, and the results obtained in the two sleep studies compared. We evaluated the efficacy and safety of unilateral renal embolization (URE) for the treatment of severe refractory hypertension in hemodialysis patients. These pattern changes were the same as in previous retinoid-treated explants. The stability of rat liver mitochondrial protein precursors in the cytosol was investigated.

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Mobile stroke unit for diagnosis-based triage of persons with suspected stroke. This is mediated by the lipid moiety of the outer surface lipoprotein A. We examined human telomerase reverse transcriptase (hTERT) protein distribution by immunohistochemistry in cultured cells and tissue sections. Successful treatment of acute respiratory failure, although difficult, can be enhanced by recognition of predisposing factors, knowledge of underlying pathophysiologic mechanisms, and early prophylactic and therapeutic intervention.

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Care transitions from the hospital to home are critical to the sustainability of our health care system. Some of the breast cancer chemotherapy trials conducted during the past 25 years were reviewed. This study determined how the luminal surface hydrophobicity and transmucosal potential difference (PD) of canine gastric mucosa changed during the recovery period after the tissue was challenged with acidified aspirin. Gonadotropin-releasing hormone (GnRH) is indispensable for reproductive activation in all vertebrates. PD patients had a significantly increased risk of malignant melanoma, a finding consistent with prior studies.

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Complications and rate of lengthenings without complication or with benign complications were studied relative to etiology, age, amount of lengthening and the stage of program in which they occurred. HOXA9 modulates its oncogenic partner Meis1 to influence normal hematopoiesis.

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Only one electrochemical HPLC method (of three tested) was successful in detecting brain nitrotyrosine. Pre- and post-loading coronal and axial gradient echo MR images with fat suppression were used to determine the patellar, tibial and femoral cartilage deformation.

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Two orthogonal circularly polarized components of the unknown polarization state of light are converted to two orbital angular momentum (OAM) modes by a q-plate, and then the OAM modes are mapped to two frequencies by using time-varying spatial modulation. To study the cause-specific prevalence of eye diseases causing bilateral visual impairment in Australian adults. Sixty per cent of patients had serum concentrations of estradiol and/or progesterone below the lower limit of normal in one or both phases of MS. The food cues appeared to generate an appetitive urge to eat in restrained eaters. Complex tetrahydrofuranyl products may be formed rapidly in high yield and with good diastereoselectivity.

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Only nine successfully performed vascularization procedures were identified. Child-focused perioperative education: helping children understand and cope with surgery. Prospective evaluation of fluorescence-in situ-hybridization to detect bladder cancer: results from the UroScreen-Study.

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In animal experiments good agreement was found between the measurements by videodensitometry and isotope technique, taking vein samples, using 125I-labelled Angiografin. Our current understanding of these processes is largely based on perceptually simple stimuli. Both M1 and M2 macrophage polarization were significantly enhanced in alveolar and peritoneal cells from F508del-CF mice as compared with control animals. Solid-phase extraction of 2 mL of milk was followed by derivatization with a trimethylsilyl reagent.

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Gelatine foam as a thrombin vehicle for hemostasis in mouth surgery Systemic adverse events were more common among healthcare workers aged less than 30 years. Combination of hypoglossal-facial nerve jump graft by end-to-side neurorrhaphy and cross-face nerve graft for the treatment of facial paralysis. These regional different effects of Angiotensin II might participate in the remodeling post myocardial infarction. Ratings by trained observers of psychiatric symptoms and psychosocial functioning improved dramatically.

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Appropriately screened women aged 50 years or older can successfully conceive via oocyte donation and experience similar pregnancy rates, multiple gestation rates, and spontaneous abortion rates as younger recipients. Chemically synthesized siRNAs were designed to target the mRNA produced by the three genomic segments. A field trial was conducted, using known negative and infected turkey flocks, and serum samples were tested by MA, SPA, and TA tests. The increase in serum 3-DG levels in the uremic patients suggests that 3-DG may be responsible for the development of uremic complications by promoting the formation of AGE.

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This map highlights PDZ domain involvement in diverse biological processes, some only found by the structure-based predictor. Magnetic resonance angiography confirmed complete occlusion of the left subclavian artery with classic subclavian steal. Taken together, our data suggest that mouse and rat fibroblasts are potential effectors in both IFN-gamma-dependent and -independent nitric oxide-mediated processes and that the patterns regulating nitric oxide metabolism in these cells are distinct from those of macrophages. MicroRNA-622 suppresses the proliferation of glioma cells by targeting YAP1.

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The number of integrants generated was directly proportional to the amount of plasmid DNA used. On day 13 after adaptation to the appropriate diet, renal clearance studies were performed to determine the effects of acute nNOS inhibition either by S-methyl-L-thiocitrulline (L-SMTC) or by N(omega)-propyl-L-arginine (L-NPA) on renal hemodynamics and sodium excretory function. Activation of Stat3 together with activating non-canonical NF-kappaB/p52 signaling by LIGHT may maximize its effects on cellular proliferation, survival, and inflammation. Of these 61 patients 55 have achieved satisfactory results, with a return of normal sexual function. The time-out was analysed quantitatively assessing compliance with a predefined observational protocol based on the checklist and qualitatively to describe reasons for non-compliance.

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Both IFNalpha and IFNgamma have been shown to exert their effects via a recently discovered signalling pathway by inducing tyrosine phosphorylation of their receptors. Lagged correlation analysis indicated that the annual fluctuation of ANNP was mainly controlled by the air temperature in a 20 years scale and had a weak 5-9 years lag effect, but there was a less correlation between ANPP and precipitation. Indication, execution and evaluation of the roentgenologic picture of jaw and teeth with special reference to the temporomandibular joint.

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Serum levels of the carboxyterminal telopeptide of type I collagen in patients with thyroid disorders The PCR product containing the four natural bases was fully digested by XbaI, while PCR products containing the modified 7-deaza-dATP analogues were not cleaved.

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Future directions will probably involve the use of new agents designed with the needs for infrequent dosing, less potential for immunogenicity and toxicity, and an expanding role in improving overall treatment outcome in mind. Diagnostic value of tests for reticulated platelets, plasma glycocalicin, and thrombopoietin levels for discriminating between hyperdestructive and hypoplastic thrombocytopenia. Effectiveness of intravesical hyaluronic acid/chondroitin sulfate in recurrent bacterial cystitis: a randomized study. Seventeen conventionally reared 3-month-old calves were divided into three groups. Histological and immunohistological analyses revealed that non-stimulated synovial fibroblasts are capable of demasking/degrading cartilage matrix components (proteoglycans, COMP, collagen) and stimulated synovial fibroblasts clearly augment chondrocyte-mediated, cytokine-induced cartilage destruction.

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Emergency physicians are usually familiar with the more common clinical symptoms but one must consider the unusual manifestations of the disease, because early recognition and initiation of therapy (steroids) decrease morbidity and can prevent blindness. Natural simian virus 40 strains are present in human choroid plexus and ependymoma tumors. The p53 protein expression was shown in both the nucleus and the cytoplasm of irradiated cells, whereas p53 was only expressed in the nucleus of control (untreated) cells.

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Circulating complement breakdown products in patients with rheumatoid arthritis. New immunosuppressive regimens in clinical intestinal transplantation. Much of the past and current focus of bioremediation has been on laboratory studies of microbial processes. Dendritic cell-tumor cell fusion vaccine prevents growth of subcutaneous transplanted esophageal carcinomas

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We aim to contribute to a deeper knowledge of the biomineralization process in calcareous dinophytes. Image registration data were used to adjust patient setups before treatment. To compare endorectal coil (ERC) and pelvic phased array (PPA) coil magnetic resonance imaging for delineation of the prostate gland and seminal vesicles. However, the analysis of these various diseases suggests that IFs also have an important role in cell-type-specific physiological functions. There were no significant associations between BP IIV and cognitive function in those aged less than 60 years.

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Hence, this is the first complete compilation of the expression pattern of all 23 human MMPs in astrocytic tumors. A dominant S-thiolated protein was N-terminally sequenced (VKVGVNGFG) and HPLC peptide mapping gave additional sequence nearer the site of oxidation (TGVFTTMEKA). Association between immunoglobulin GM and KM genotypes and placental malaria in HIV-1 negative and positive women in western Kenya. SDQ-HI was associated with an increased risk for overweight/obesity in both sexes adjusting for age and sex. Aggressive systemic mastocytosis after germ cell tumor of the ovary: C-KIT mutation documentation in both disease states.

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A conventional grid also improved the image noise, though the improvement was less than that of focused collimators. Phosphatidic acid is the product of two signalling pathways, those of phospholipases C and D, the former in combination with diacylglycerol kinase.

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Primary rat astroglial cell cultures were treated either with hydrogen peroxide (H2O2), as a direct mediator of oxidative stress, or with the redox cycling compound paraquat. Therefore, in this condition, early NK immune-modulation might improve HSCT outcome. A unique cathepsin-like protease isolated from CV-1 cells is involved in rapid degradation of retinoblastoma susceptibility gene product, RB, and transcription factor SP1. Baseline global cognitive function and change in global cognitive function were associated with physical performance change, but baseline physical performance was not associated with cognitive change in this cohort. Based on this analysis, there were characterized five molecularly different subclasses: basal-like, luminal type A and B, HER-2, and unclassified.