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This paper is a sequel to that of McMillan (1997) and describes further assessment of an extremely severely head injured patient. This is the first report demonstrating the potential predictive value of STAT1 activation status in patients with squamous cell cancer of the oral cavity.

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Incidence of acute myeloid leukemia and hepatocellular carcinoma in mice irradiated with 1 GeV/nucleon (56)Fe ions. Fractional processing of sequential bronchoalveolar lavage fluid from intubated babies. Widespread B29 (CD79b) gene defects and loss of expression in chronic lymphocytic leukemia.

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The students attached the highest importance to the insights gained into patients and their experience of illness. Luminescent visualization of low amounts of cytochrome P450 and hemoproteins by luminol in acrylamide gels. Productive directions for research in this field are likely to lie in areas where disease outcomes are dependent on environmental intermediaries, such as vector borne or water borne infectious diseases, and the paper provides one worked example using allergy to ant stings as a case study. Auditory event-related response in visual cortex modulates subsequent visual responses in humans.

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Little evidence is available regarding restrictions from driving following implantable cardioverter defibrillator (ICD) implantation or following first appropriate or inappropriate shock. Lipid reorganization induced by Shiga toxin clustering on planar membranes. Effect of modern, high-quality prostate intensity-modulated radiation therapy on outcome: Evidence from a community radiation oncology program.

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Merozoite surface proteins of the human malaria parasite Plasmodium falciparum are involved in initial contact with target erythrocytes, a process that begins a cascade of events required for successful invasion of these cells. By virtue of the negative charges they carry at their headgroup, they contribute to the surface charge of the membrane and may affect ion distribution, mainly that of protons and calcium ions, at the outer side of the membranes. The blunted cardiac contractility of cirrhosis was associated with decreased membrane fluidity and diminished beta-adrenergic receptor signalling.

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Inactivation of Ichthyophonus spores using sodium hypochlorite and polyvinyl pyrrolidone iodine. The TATA-binding protein is not an essential target of the transcriptional activators Gal4p and Gcn4p in Saccharomyces cerevisiae. To confirm these findings an additional analyses might need to be performed using a larger sample size. As found previously, proliferating spermatogonial stem cells were much more radioresistant than quiescent stem cells. In recent years, major advancements in single-cell measurement systems have revolutionized our understanding of the pathophysiology of AML and enabled the characterization of LSCs.

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EEG was undertaken using a computer-assisted portable EEG recorder. These differences are apparently not determined by phylogeny, but may relate to the timing of development of relative hypoxia as an embryo develops, which is related to birthing strategy. This review can serve as a basis on which to select pragmatic, cost-effective biomonitoring techniques for environmental effects in lagoon ecosystems. Phylogenetic analyses of ncLSU, ncSSU, ITS and tub2 sequence data lead us to propose two novel families in Sordariomycetes, Acrodictyaceae and Junewangiaceae. The ridges were equally spaced (approxamately 245 A spacing) along the length of the transition region.

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In contrast, new legal theories focusing on proactive and therapeutic dimensions in law have gained increasing attention in the international arena. The main analysis compared alcohol withdrawal severity scores and medication doses for 24 h before dexmedetomidine therapy with values during the first 24 h of dexmedetomidine therapy.

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Hepatopancreas glycosidases of the abalone (Haliotus rufescens). In diverse eukaryotic species from yeast to human, TOR (Target Of Rapamycin) protein kinase operates in signaling pathways that link extracellular stimuli to the control of cell growth and metabolism. Effects of equine joint injury on boundary lubrication of articular cartilage by synovial fluid: role of hyaluronan. A case of biphenotypic blast crisis of unclassified myeloproliferative disorder.

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The Gold Standards Framework was developed in primary care to improve the care provided for people at the end-of-life. In one arm of the study, FFR-rFVIIa (0.2 mg in 150 microL) or vehicle alone was applied topically at the site of vascular injury. These results suggest that the decrease in macroscopic Na currents is due to a decrease in channel open probability (P(o)), suggesting that mutations of a conserved glycine in the N-terminus of ENaC subunits change ENaC channel gating, which would explain the disease pathophysiology.

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This study presents data documenting the effect of a maintenance program on the long term (2-year) adjustment of a group of patients with OCD treated with exposure and response prevention. In the present study we demonstrate for the first time that the use of an elastin-like recombinant polymer (ELR) engineered to contain the cell adhesion peptide RGD can result in a 3D tissue equivalent with high self-renewing potential, containing as many proliferative cells as the native tissue itself. An immunocytochemical marker for the complex granules of tick salivary glands which traces e-granule shedding to interstitial labyrinthine spaces.

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With this procedure, 1-50 live target cells can now be isolated. Changes in cardiovascular morbidity and mortality were the primary outcomes of interest. The effect of concealed concomitant anal incontinence symptoms in patients with urinary incontinence on their quality of life. However, for many applications, working at subnanometer resolution implies an exceedingly large number of scanning points.

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A gliding bacterium strain inhibits adhesion and motility of another gliding bacterium strain in a marine biofilm These results provide direct evidence that the amino acid at position 309 is an important determinant for the picrotoxinin sensitivity of GABA receptors formed by the rho subunits. DM1 is triggered by the pathological expansion of a (CTG)(n) triplet repeat in the DMPK gene, whereas a (CCTG)(n) tetranucleotide repeat expansion in the ZNF9 gene causes DM2. The nucleotide sequence of a mouse cDNA encoding the 80 kDa subunit of the Ku (p70/p80) autoantigen. Study results demonstrate that consumption of PS-Omega3 by children with ADHD, as indicated in a 30-week evaluation period, is safe and well tolerated, without any negative effect on body weight or growth.

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Effect of ligand concentration on the precision of determining the parameters of ligand-receptor interaction by serial dilution methods The potential effect of renal lesions on renal function was evaluated five years after transplantation. Evidence that xenogeneic immune RNA (I-RNA) mediated specific cytotoxic immune responses against human tumor-associated antigens was obtained from in vitro studies in two autologous melanoma systems. The activity of aldehyde dehydrogenase (ALDH) was measured in primary and metastatic human colonic adenocarcinomas. After initial improvement of nerve conduction in both groups, probably caused by the elimination of uremia, further improvement was seen only in the euglycemic pancreas-graft recipients.

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Although nicotine itself may not be a desirable therapeutic agent, because desensitization of nicotinic receptors limits the time course of its effect, the study identifies a previously unexploited therapeutic target for new drug development for the neuropsychiatric sequelae of cocaine addiction. Sulfaquinoxaline, nitrofurazone and nitrophenide in the prophylaxis of experimental Eimeria necatrix infection.

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Globally, physicians demonstrated deficits in basic treatment principles, including the role of viral kinetics and the management of treatment nonresponders. Unregulated or uncontrollable DNA replication is well known to result in many pathological states, such as cancer, autoimmune diseases, and viral/bacterial infections. The present study examined the relative contribution of these two sources of support to life satisfaction among Chinese older adults living in Hong Kong. Acetylation of the epsilon-amino group of lysine residues (N(epsilon)-acetylation) is a reversible post-translational modification with the potential to rival phosphorylation. Mutants contain no detectable nrf mRNA and die within 2 weeks postfertilization as larvae with reduced brain size.

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An anonymous questionnaire was used to collect data from 2007 to 2008. Isolation of a novel plant lectin with an unusual specificity from Calystegia sepium. Increased oxygen radical and eicosanoid formation in immune-mediated mesangial cell injury. Dystrophin deficiency causes muscle membrane lesions, muscle degeneration and eventually death in afflicted individuals. The Challenger accident prompted the creation of a crew escape system which replaced the former Launch Entry Helmet (LEH) ensemble with the current Launch Entry Suit (LES).

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Study of gastric secretion in the anesthetized rat induced by caerulein, histamine and carbachol Simple method of fluid resuscitation in patients requiring emergency thoracotomy through direct cardiac cannulation. We present a case of a 73-year-old man with a previous history of prostate cancer that had the incidental finding of an (18)F-fluorodeoxyglucose (FDG) image of a highly avid parapharyngeal space lesion noted on a follow-up positron emission tomography-computed tomography (PET/CT) scan. In persons under 65 years of age, the world age-standardized mortality rate is expected to increase, but the number of deaths in this age group is expected to nearly double between 2002 and 2015.

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We determined whether standing changed standard measurements of acetabular component position using a novel biplanar imaging system compared to traditional supine imaging. For patients who cannot have open heart surgery, minimally invasive procedures are making it possible to get new valves and a new lease on life. Fingerprint-based in silico models for the prediction of P-glycoprotein substrates and inhibitors.

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Sensitivity and specificity of human immunodeficiency virus rapid serologic assays and testing algorithms in an antenatal clinic in Abidjan, Ivory Coast. Although non-adhesive throughout most of the menstrual cycle, epithelial cells allow attachment of trophoblast cells to their apical pole during embryo implantation. Computerized prescriptions allow the evaluation of antibiotic therapy even when the infectious diseases specialist intervention is short. The frequency of the Wr-a, By and Mg blood group antigens in blood donors in the south of England. We further uncovered how network characteristics affect the evolutionary and co-evolutionary behavior of proteins and how protein evolution can modify the existing functionalities of signaling networks.

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We analysed 13 SCA2 patients in seven unrelated families in Gunma Prefecture, Japan. Only small series and several case reports on isolated FTT have been published in the literature. Our initial search retrieved 297 articles listed on MEDLINE, Google Scholar, CINHal and EMBASE. These results indicate that miR394 and its target LCR are involved in the regulation of leaf development.

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Physicians feel that they have too little time, are not trained to deliver preventive services, and are concerned about the effectiveness of prevention. Experimental model of functional pathology of the tooth-jaw system in secondary partial anodontia (clinico-roentgenologic study) Practitioners of evidence-based practice need a basic understanding of these principles to critically appraise the results of research studies. All-optical image processing with cavity type II second-harmonic generation. High-resolution ultrasonography and 3.0 T magnetic resonance imaging in erosive and nodal hand osteoarthritis: high frequency of erosions in nodal osteoarthritis.

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Matching arthropod anatomy ontologies to the Hymenoptera Anatomy Ontology: results from a manual alignment. The annual linear wear rate of polyethylene cups with alumina heads was less than that of cups with cobalt-chromium alloy heads. Acute small bowel obstruction due to ileal endometriosis: a case report and review of the most recent literature.

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The influence of intermittent fasting on the circadian pattern of melatonin while controlling for caloric intake, energy expenditure, light exposure, and sleep schedules: A preliminary report. Project Exhale: preliminary evaluation of a tailored smoking cessation treatment for HIV-positive African American smokers. Voltage-activated transport of ions through single-walled carbon nanotubes.

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Interestingly, each combination of double mutants between pad1-1, pad2-1 and pad3-1 exhibited additive shifts to moderate or full susceptibility to most of the isolates. Protein hydrolysates and their use in chronic diseases of the intestine Whole-genome sequencing of Campylobacter jejuni isolated from Danish routine human stool samples reveals surprising degree of clustering.

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In this case-control study investigating elastin changes in postmenopausal women with prolapse, the elastin expression and fibre width were significantly lower in the vaginal wall of patients with a large cystocele than in controls of a similar age. In contrast to the skin of the untreated homozygous pups, which expressed high levels of HIV mRNA and proteins (i.e., gp120 and Nef), the skin of the hCG-treated pups showed a marked reduction in both HIV mRNA and proteins. The anomalous artery was successfully reimplanted into the aorta. Increased vitamin D serum levels correlate with clinical improvement of rheumatic diseases after Dead Sea climatotherapy. Some patients had convex expiratory P-V curves even with low pressure swings during tidal ventilation.

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Genetic analysis of fish iridoviruses isolated in Taiwan during 2001-2009. Can pediatric electrophysiologists safely perform electrophysiology studies on adults with congenital heart disease? Of the 28 patients, 19 were women and the mean age was 79 years (range, 52-95 years). A simple strand-specific RNA-Seq library preparation protocol combining the Illumina TruSeq RNA and the dUTP methods. These studies emphasize the important role of protein-protein interactions in Rel and NFkappaB-mediated transcription.

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Parasitization by pteromalid wasps (Hymenoptera) of freeze-killed house fly (Diptera: Muscidae) puparia at varying depths in media. Use of maximum length sequence analysis in newborn hearing testing. These techniques will certainly enable a better evaluation of initial cardiovascular injury and allow the correct, timely management of obese patients. The Drosophila melanogaster homolog of the mammalian MAPK-activated protein kinase-2 (MAPKAPK-2) lacks a proline-rich N-terminus.

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The aim of the present study was to gain an understanding of how nursing staff experienced participating in a training programme aimed at strengthening their self-esteem and empowering them, to determine whether participation benefited them in any way, and to describe their opinions about possible benefits or disadvantages. The clinical and pathological data of 300 colorectal cancer patients with liver metastases were retrospectively reviewed and analyzed. The epidermal growth factor (EGFR) plays an important role in the development and progression of colorectal cancer. In this study, we examined the extent to which aggregate racial differences are attributable to variations in the distribution of individual and family-level risk factors.

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The granulation tissue weight, its breaking strength and its hydroxyproline content was also increased by the extract in the dead space wound. Taken together, seminal plasma stimulates COX-2-PGE2-Sp1-dependent hTERT transcription, which provides insights into the putative mechanism underlying telomerase activation in cervical epithelial and cancer cells.

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Using pairs of smooth and rough forms of Enterobacteriaceae, six smooth-specific bacteriophages were isolated from sewage and another was obtained from Dr Hedda Milch, Budapest. In addition, the anatomic and hemodynamic factors that determine whether an infant with severe PS will present with cyanosis or without symptoms are not well understood. The precoating of the expanded polytetrafluoroethylene prosthesis was done with fibrinolytically inhibited fibrin glue. Data were collected from 1902 males randomly selected from participants of a cohort study. However, another New World monkey, the cotton-top tamarin, carries only one semenogelin gene, but also has a gene that is similar to the mouse semenoclotin gene.

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The addition of liposomal muramyl tripeptide phosphatidylethanolamine (MTP-PE) to chemotherapy has been shown to improve overall survival in patients with nonmetastatic osteosarcoma (OS). To reduce risk of vertical transmission of HIV and in cases of infertility, people with HIV should have access to sperm washing and other assisted conception methods, if these are available. Sixteen clinical variables were examined by using univariate and multiple logistic regression analysis to identify the predictors of recurrent ischemia. Case records of the Department of Medicine University of Mississippi Medical Center.

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The postcranial anatomy of Suminia provides the earliest skeletal evidence for prehensile abilities and arboreality in vertebrates, as indicated by its elongate limbs, intrinsic phalangeal proportions, a divergent first digit and potentially prehensile tail. The prevalence of skipping breakfast is significantly higher compared recently reported figures for medical students in western countries and other areas of China. End-product inhibition of delta-aminolevulinic acid synthetase in the mitochondria may play an important role in the regulation of heme biosynthesis in eukaryotic cells. Results of the examination of pigeons for ornithosis in Moscow and vicinity These clones were used as probes to examine changes of gene expression that occurred after the proliferation of exponentially growing primary human fibroblasts was arrested.

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Field observation of advance warning/advisory signage for passive railway crossings with restricted lateral sightline visibility: an experimental investigation. Spinal dural arteriovenous fistulas are rare spinal vascular malformations which can cause progressive paraparesis and paraplegia if not treated.