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Lexamil (Escitalopram)

Lexamil is the S-isomer of the racemic compound citalopram, a selective serotonin reuptake inhibitor (SSRI) that is widely used in both psychiatric and primary care practices for the treatment of depression. The theoretical rationale for separating a single isomer from its parent compound and synthesizing it into a new therapeutic agent is 2-fold. First, it may capture the molecule that is actually responsible for the desired therapeutic action. At the same time, it may isolate and remove the molecule that is not only therapeutically unproductive but may be the source of undesirable pharmacologic activity. The result is a “purer” agent, one that can potentially offer an improved safety and efficacy profile versus the parent compound.

Other names for this medication:
Escitalopram, Lexapro, Aramix, Celtium, Cipralex, Citoles, Ectiban, Entact, Esertia, Esipram, Esita, Eslorex, Esram, Gaudium, Lexamil, Lextor, Losiram, Losita, Neozentius, Nexcital, Seroplex, Sipralexa, Tiopram,

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LSHKO mice gained less weight and exhibited increased energy expenditure compared with control mice. Pharmacogenetics of acenocoumarol: cytochrome P450 CYP2C9 polymorphisms influence dose requirements and stability of anticoagulation.

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Histologically, the lesion was consistent with mammary-type myofibroblastoma of soft tissue, a very rare, benign mesenchymal neoplasm with myofibroblastic differentiation. Metabolic-dependent changes in plant cell redox power after ozone exposure.

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No highly significant associations existed between age at smoking initiation, pack-years smoked, duration of smoking, and time since quitting smoking as predictors of individual CpG site methylation levels. Optimization of immunohistochemical staining of proliferating cells in paraffin sections of breast carcinoma using antibodies to proliferating cell nuclear antigen and the Ki-67 antigen. In both cases we found that the pressure inside a liquid film was constant, while temperature decreased and density increased as a function of distance from the middle of the film.

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New high-pressure structural transition of oxygen at 96 GPa associated with metallization in a molecular solid. This paper presents a flexible random-effects approach to model heterogeneous nest survival data. To be complete, such a program requires the further refinement of behavioral objectives that allow reliable evaluation and redefinition by residents and faculty. The health care work environment and adverse health and safety consequences for nurses.

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Various experimental models have been developed in order to more clearly understand deep vein thrombosis, the mechanisms involved and its treatment. Between 2005 and 2011, 235 patients underwent bariatric surgery for morbid obesity.

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Phagocytized spores were also found in the epidermis of skin and within melanomacrophage centers in the kidney. Clinical evaluation of squamous cell carcinoma antigen in squamous cell carcinoma arising in mature cystic teratoma of the ovary.

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By fluorescence in situ hydridization the selected sequences are shown to be localized at the centromeric regions of mouse metaphase chromosomes. The antitumor activity was most prominent in the HRT G2b isotype among HRT mAbs.

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Interference mapping of nuclear protein binding to the acute phase response element of the mouse alpha1 acid glycoprotein gene. At the concentrations existing in BB, isoflavones such as genistein and daidzein could not attenuate collagen-induced platelet aggregation, however, adenosine significantly inhibited platelet aggregation with an equivalent potency to BB, suggesting that adenosine may be the major bioactive component. Moreover, the 250-kD PG is present in embryonic chick retina and brain and is associated with the GalNAcPTase in situ. Observations from the realm of the dream compared with conceptual development in children

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we conducted cross-sectional comparison of ARFI imaging and transient elastography on patients who underwent liver biopsy at Cipto Mangunkusumo Hospital. Submandibular space swelling in a patient with fibrodysplasia ossificans progressiva: a diagnostic dilemma.

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Hepatitis C virus-associated cryoglobulinemia with membrano-proliferative glomerulonephritis treated with prednisolone and interferon: A case report. To assess the use of endoanal ultrasounds to identify anal pain etiology in patients with either spontaneous or post-operative pain, and to review the most frequent causes.

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This case has shown that one critical component for a high success rate is the tamponade agent used in the vitreous. The left ventricle can be biopsied in disease states affecting that chamber, viz.

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This article reviews the literature and proposes guidelines for the management of patients taking anticoagulant and anti-platelet agents who require gastrointestinal endoscopy. The current model analysis emphasizes the role of spatial information flow in development.

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The urinary excretion of collagen degradation products by quadriplegic patients and during weightlessness. We previously described that murine resident alveolar macrophages, which play a central role in the immunosurveillance of the lung alveoli, do not synthesize IL-10 in vivo or in vitro when exposed to LPS. A retrospective study was conducted to determine which types of children might have polysomnographic findings that are most compatible with obstructive sleep apnea (OSA). To understand the relationship between novel parainfluenza virus 3 (PIV-3), which has recently been isolated from the lungs of guinea pigs, and other PIV-3 strains, we determined the complete nucleotide sequence of the novel PIV-3 (GPv) genome.

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During an overnight stay outside the hospital, he experienced sudden lumbago while removing snow at his home. This review describes some of the evidence that supports the use of TDM/TCI in oncology. Clinical deterioration during antitubercular treatment at a district hospital in South Africa: the importance of drug resistance and AIDS defining illnesses. These data showed that sputum neutrophila can be dissociated from airway symptoms and could create a favorable background for the development of age-related lung diseases.

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Antimicrobial susceptibility pattern of urinary tract pathogens. Reciprocal recombination between alleles accounts for only a minor fraction of the total aberrant tetrads, while the majority component is represented by single- and double-site conversions. The possibility that the glucose-induced improvements in reaction time reflect an increased synthesis of acetylcholine is discussed.

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Eukaryotic proteasomes have multiple catalytic activities which are catalysed at distinct sites. Department of Veterans Affairs, it shows that performance-driven human resources practices play an important role as determinants of employee customer orientation and service capability in both high-contact (outpatient healthcare) and low-contact (benefits claim processing) human service contexts. Notwithstanding this proliferative effect, we have shown that a novel isoform of NDF can induce apoptosis when overexpressed. Astrocytes and lentivirus infection in an experimental models of macaque infected with SIVmac251

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New demands for advanced options are coming from (medical) biology, biotechnology, pharmaceutical and nutrition research. Growth hormone-releasing hormone: cerebral cortical sleep-related EEG actions and expression. This assessment should be performed at the same time as the locoregional and remote extension assessment, and is obviously to be adapted according to tumoral extension stage and the possible treatment options.

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However, most studies include only subtype B strains, while it is known that especially the env region is very divergent among subtypes. OC use seems to eliminate cyclic fluctuations in caloric intake. Although total cellular proteins were synthesized independently of the cell cycle, the synthesis of membrane-bound proteins was found to be dependent on the cell cycle, the time of maximum synthesis being just before that of maximum DNA synthesis. Isotropic DWIs, trace apparent diffusion coefficient (ADC) maps, and fractional anisotropy (FA) maps were created for each b value.

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As housestaff will be training and practicing in an environment where costs and quality will be intertwined, chief residents, with their credibility, contacts, and concern, can help incorporate CQI into the environment of graduate medical education. It is suggested that the Z-line component is related to the formation of the cytoplasmic body in skeletal muscle and disarray in the cardiac muscle.

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Western blot analysis using affinity-purified serum against the amino terminus of the OCRL-1 gene product (ocrl-1) demonstrates a single protein of 105 kD in fibroblasts of a normal individual that is absent in fibroblasts of an OCRL patient who lacks OCRL-1 transcript. In view of the similarities between reversible vacuolation in the T-system and membrane transformations occurring in a variety of non-muscle cells, it is suggested that reversible vacuolation in T-tubules may be regarded as a general model for tubular-vesicular transformations in biomembranes. A comparative K- and L(3)-edge XANES data analysis is presented, demonstrating the clear advantages of the L(3)-edge XANES analysis over the K-edge studies for structural investigations of lanthanoid compounds. Evaluation of clarithromycin resistance and cagA and vacA genotyping of Helicobacter pylori strains from the west of Ireland using line probe assays.

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These specimens were evaluated for the presence of beta 2-microglobulin (beta 2m) amyloid by Congo red and immunohistochemical staining. Optic neuritis or longitudinally extensive myelitis in Sjogren syndrome (SS) suggests a neuromyelitis optica spectrum disorder (NMOSD).

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The present results of total PBDEs in sediment and fish were 10 and 1000 times higher than other studies. Polymerase chain reaction and flow cytometry were simultaneously applied for prospective minimal residual disease measurements at days 15, 33 and 78 of induction therapy on 3565 samples from 1547 children with acute lymphoblastic leukemia enrolled into the AIEOP-BFM ALL 2000 trial. Emergent intubation is associated with a high rate of complications. As a result of intense genetic studies of families with specific mutations, the road to better therapeutic intervention for pheochromocytoma (PHEOs) and parangangliomas (PGLs) has more recently become populated with several promising molecular targets. One approach to addressing this need is through high-throughput screening of drug-like small molecule libraries against the whole bacterium in order to identify a variety of new, active scaffolds that will stimulate additional biological research and drug discovery.

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Inhibitory effect of curcumin on motility of human oral squamous carcinoma YD-10B cells via suppression of ERK and NF-kappaB activations. Confirmation of chronic hyperglycemia is essential for the diagnosis of diabetes. Eventually dynamical frustrated states appear, where the temporal evolution is chaotic, even though there are no built-in frustrations. Thus, we critically reviewed the evidence supporting the prognostic value of two frequently-used measures, the Barthel Index (BI) and modified Rankin Scale (mRS) for long-term outcomes. Generally, those children with persistent symptoms of sinonasal polyposis are referred to an otorhinolaryngologic (ORL) physician for sinus surgery.

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The dorsal root ganglia (DRG) containing the primary sensory nerve cells had been surgically removed in order for secondary or spinal cord sensory neurons to extend into the periphery and replace the deleted DRG neurons. Preliminary research on the experimental antineoplastic activity of the combination of N-diazoacetylamino acids and 6-mercaptopurine Internationally based cut-off points have now been published, and a British study reports trends in overweight and obesity in children, as defined by these.

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The expression of b-defensins was very variable in both sulcular and gingival epithelium. The external marker device is placed on the abdominal region between the xyphoid process and the umbilicus of the patient.

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This case demonstrates that heterokaryotypic monozygotic dichorionic twins are a genetic possibility that does occur. Carotid angioplasty and stenting (CAS), however, has been proposed as alternative therapy for patients deemed at high-risk for CEA.

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When compared with normal C57 mice, DBA mice showed significant reductions of the a-wave and b-wave amplitudes by 7 to 8 months, and the decline continued as the animals aged. In four patients final foot position was not an optimal one for hindfoot arthrodesis. In reoperative cases, it is easier to approach the circumflex coronary artery from the left side than from the front. Despite the conservative design constraints and associated data analyses (correlations were not corrected for attenuation), some systematic effects were observed. Scientists at the National Institutes of Health have reported that increased coffee consumption is associated with a slower progression of fibrogenesis in patients with chronic and particularly alcoholic liver disease and a reduced incidence of heptocellular carcinoma.

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Two algorithms for estimating Markov chain models in the case of intermittent missing data in longitudinal studies, a stochastic EM algorithm and the Gibbs sampler, are described. To describe the clinical features, treatment and outcome of children adrenal tumors presenting with hypertension. Illness and injury to travelers and access to dental care on a research expedition to Mongolia. Cortical excitatory glutamatergic projection neurons and inhibitory GABAergic interneurons follow substantially different developmental programs. A physiologically-based pharmacokinetic and pharmacodynamic (PBPK/PD) model was recently developed to study the effect of diisopropylfluorophosphate (DFP) on acetylcholinesterase (AChE) activity in mouse and rat.

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Cats are considered to be the natural reservoir and infection sourse of this disease in human and domestic animals. We propose a new set of approaches, which allow identifying the primary enzymes of glyphosate (N-phosphonomethyl-glycine) attack, measuring their activities, and quantitative analysis of glyphosate degradation in vivo and in vitro. Phylogeny of Litsea and related genera (Laureae-Lauraceae) based on analysis of rpb2 gene sequences. The biological exposure indices: a key component in protecting workers from toxic chemicals. In this report, we systematically examined the ability of all members of the P2X receptor family to interact using a co-immunoprecipitation assay.

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Hypertonic NaCl inhibits gastric motility and food intake in rats with lesions in the rostral AV3V region. Onset of oestrogen-induced prolactin secretion and DNA synthesis by the rat pituitary gland. In the five highest-scoring sections, the scattering was lower than in the other five. Comparison of five retrovirus vectors containing the human IL-2 receptor gamma chain gene for their ability to restore T and B lymphocytes in the X-linked severe combined immunodeficiency mouse model. We examined studies that are engaged in problems of hypocholesterolemia in critically ill.

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Evidence is provided for the specific activation of the locus coeruleus noradrenergic system of the rat by novel stimuli encountered while investigating the environment, as well as during a formal learning situation. Selected case studies are presented to describe important knowledge, methodologies, techniques, principles, and practices for sustainable development emerging from developing countries in two critical challenge areas to sustainability: water and energy. In this paper, the authors discuss a 57-year-old woman who presented a jaundice related to hepatobiliary cystadenoma. Thirty-eight patients were identified for whom long-term supplementation with vitamin D was indicated.

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These BAC features led to the proposal of a new approach to sequence the human genome. Prophyromonas gingivalis fimbriae mediate coaggregation with Streptococcus oralis through specific domains. Paliative procedures in cholangiocarcinomas--experience of 5 centers Humans, bushbabies, frogs, locusts, fleas and other animals jump by rapidly extending a pair of legs. Mount Sinai Hospital, New York City, an urban, tertiary care institution.

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The gene is composed of nine exons spanning a genomic region of approximately 4 kb. Modified Alvarado scoring system was evaluated regarding its usefulness in the early diagnosis of acute appendicitis and in reduction of the incidence of negative appendicectomies. Development of agriculture left-overs: fine organic chemicals from wheat hemicellulose-derived pentoses. Concurrent osteochondroma and osteoblastoma of the proximal humeral shaft.

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However, since it has been shown that lower urinary tract manipulations, including transurethral prostatectomy, do not significantly increase serum creatine kinase isoenzyme MB levels, such elevations, which are found in patients after prostatic surgery, are believed to be specific for myocardial infarction. Proteoglycan synthesis of chondrocytes of immature articular cartilage. Utilization of MRI studies for radiological examination of cancer during pregnancy is recommended. Survival in families with hereditary protein C deficiency, 1820 to 1993.

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Since inflammation can cause increased adhesiveness of peripheral white blood cells (WBC), we compared these adhesive properties in individuals with viral infection to those with nonviral infection/inflammation. We propose that understanding recruitment as a phased process can enhance design and conduct of trials, supporting completion on time, on budget. We also tried to reconcile the paradoxical results and highlight the new findings concerning the function of MAPK in both oocytes and the surrounding follicular somatic cells. Our findings support the potential targeting of survivin and cortactin for the development of novel therapeutic strategies for renal cell carcinoma.

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In this study, we have investigated the effect of eCG on steroid production by the corpus luteum (CL) during equine pregnancy. Prior exposure to aminopenicillins in the neoplasm group might contribute to this finding. The searches were undertaken in March to April 2008 and June 2009. The objective of this study was to determine the time required for equilibration of oxygen saturation (SpO2) and the oxygen flow rate that might predict readiness for oxygen weaning to room air in preterm infants with improving bronchopulmonary dysplasia (BPD).

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Eradication therapy was given with a four drug regimen and repeat endoscopy was done three months later to detect ulcer healing as well as H. The survey sought to characterize nutritional status and other health measures in indigenous children less than 5 years of age and indigenous women from 14 to 49 years of age on the basis of a survey employing a representative probabilistic sample of the indigenous population residing in villages in Brazil, according to four major regions (North, Northeast, Central-West, and South/Southeast). Searches of PubMed and unpublished data yielded a total of 18 cohort studies of women occupationally exposed to asbestos. The preparation of primary hematopoietic cell cultures from murine bone marrow for electroporation.

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Hydroxyl radical scavenging mechanism of human erythrocytes by quercetin-germanium (IV) complex. Because adenosine alters endocrine function and endocrine cells secrete cytokines, its effects on IL-6 and TNF release from rat adrenals, ovaries, and anterior pituitaries were compared with its effects on cytokine release from rat peritoneal macrophages. This study aimed to evaluate the effect of megestrol acetate (MA) on serum albumin levels in malnourished dialysis patients. Tomato sauce supplementation and prostate cancer: lycopene accumulation and modulation of biomarkers of carcinogenesis. Optical microscopy and atomic force microscopy show that the large-scale arrays are oriented parallel to the pulling direction and are well adhered to the substrate surface.

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Elbow arthroplasty most commonly is performed through a posterior approach by detaching or reflecting emimycin uses the triceps off the olecranon. Experiments were performed to determine whether prohibitin, an evolutionarily conserved gene with antiproliferative activity, has a role in cellular immortalization.

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However, 5,7-dichlorokynurenic acid (5,7-DCK), an antagonist for the glycine site on the NMDA receptor, reduced the ganglion cell responses to NMDA puffs, and reduced the potassium puff- and light-elicited EPSCs. Digital counts were highly correlated with manual counts for medium to augmentin 1 gm in pregnancy high parasite densities, and slightly less well correlated with conventional counts. Large-scale preparation of sodium-potassium ATPase from kidney outer medulla.

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Looks so bad, feels so good--Hollywood takes on social activism. Similar results are obtained analyzing the effect of immunosuppressive drugs. Moreover, cytokinin receptor mutants also showed a reduced response, suggesting a previously unrecognized function of phyD and cytokinins. In addition to providing a valuable in vivo model of retrotransposition in mammals, these mice are an important step in the development of a new random mutagenesis system. Caco-2 cells, a well-established cell model, were incubated with butyrate (2.5-20mM) with or without flutec medicine ball carnitine (10mM) for various incubation periods.

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Since recently diverged populations have high levels of shared polymorphisms, it is challenging to distinguish between recent divergence with no (or very low) inter-population gene flow and older splitting events with subsequent gene flow. The diagnosis methods and ketipinor 25 mg vaikutus surgical techniques are also mentioned.

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The inertia, the viscous friction, the kinetic friction, the motor back-electromotive force constant, and the motor constant were calculated using three valacyclovir hcl 1 gram tablet drug interactions different methods. However, CABP needs to be promptly recognized because mortality is higher in these patients.

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This suggests that the loudness of the masking tone influences the tinnitus masking phenomenon. Subject differences in luminosity using absolute threshold and CFF techniques. The size of the field of view is increased allowing regularly the single dose azithromycin and alcohol visualization of the whole facial skeleton. Suppression of TLR signaling by targeting TIR domain-containing proteins. Problem gambling severity and the incidence of Axis I psychopathology among older adults in the general population.

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Review: General health checks in adults do not reduce all-cause, cardiovascular, or cancer mortality. However, the expression of miR-17-5p in HCC tissues and its clinical relevance has not been systematically studied yet, and whether syrio forel vs meryn trant why does arya miR-17-5p expression has influence on prognosis of HCC is still unknown. Histological analysis showed that group 4 exhibited the largest bone formation area. Further research is needed to clarify negative and positive effects of muscular coactivation during walking in fearful subjects. The Nd:YAG laser was used for the disruption and removal of corneal calcium deposits.

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In this paper the effect of concentration of cosolvent (methanol) for the formulation of particles size has been discussed briefly. Our model system provided a unique opportunity to distinguish the molecular changes associated with T/HS-induced acute lung injury from the systemic molecular response to T/HS. avix booster ingredients in meth Epithelioid hemangioendothelioma after radiotherapy for congenital hemangioma: a case report. The effect of cocoa upon calcium utilization and requirements, nitrogen retention and fecal composition of women.

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More information is now taken into account to decide on treatments. Australian medical educators should build on ketoconazole side effects topical the recent reforms and take on some of the new directions in medical education. Biophysical particle characterization demonstrated that lyophilization and powderization in the presence of lyoprotectants were well tolerated.

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AVP is a major transcriptional activator of the AQP2 gene, and stimulation of insulin- and calcium-sensing receptors respectively potentiate and reduce its action. Regional differences in surface cytology of smokers and nonsmokers. Many of the syndromes associated with PCVAD are a result klecker klax review of systems of coinfection with PCV2 virus and other agents such as Mycoplasma and porcine reproductive and respiratory syndrome virus. One year and 1 month postoperatively, the patient is alive without recurrence.