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Here we describe the molecular cloning of the human and mouse genes encoding CNTFR. Pigeons were trained to discriminate among saline, 5 mg/kg morphine, 5 mg/kg pentobarbital, and a mixture of these two doses using a four-choice procedure. To illustrate the utility of Gene RECQuest we used it to identify genes physically located within a linkage region as potential candidate genes for a quantitative trait locus (QTL) for very low density lipoprotein (VLDL) response on chromosome 18.

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Arterial revascularisation with the conjoined double internal mammary artery grafting. Expression of the GUS fusion gene controlled by the tomato rbcS3A promoter in transgenic rice Does the location of thrombosis determine the risk of disease recurrence in patients with proximal deep vein thrombosis?

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In yeast, actin cables direct exocytosis to the bud and to the tips of polarized mating intermediates termed shmoos. Analysis of adverse reactions induced by subcutaneous immunotherapy against dust mite allergy in 234 cases with allergic rhinitis and asthma We performed end-to-end arterial repairs in seven fingers, vein graft repairs for arteries in two fingers, arteriovenous anastomoses in three fingers.

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Subjects received either a 10-mg bepotastine OD (orally disintegrating) tablet or a placebo 10 min before entering the chamber for a 3-h exposure. The paper concludes with a consideration of the role in the development of professional knowledge and strategies for knowledge development. Inhibition of Snail expression using small interfering RNA techniques increased adiponectin expression in 3T3-L1 adipocytes, while overexpression of Snail reduced adiponectin expression. Telomeres were significantly shorter in all mouse strains with constitutional chromosomal aberrations in comparison with those originating from the karyatypically normal mouse from the same genetic background. A review of the planning process, implementation strategy, and fund-raising experience is presented.

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Method for Assigning Priority Levels in Acute Care (MAPLe-AC) predicts outcomes of acute hospital care of older persons--a cross-national validation. Furthermore, using models of chronic kidney injury it was demonstrated that fibrosis can also be blocked using treatment with the antagonist of A2B receptor subtype. Advances in technology and surgical techniques have essentially replaced ablative procedures for most of these conditions. Cost-effectiveness of a primary care based physical activity intervention in 45-74 year old men and women: a randomised controlled trial.

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This article summarizes current data on the use of these markers in prognostic evaluation. SAR131675 had no antiproliferative activity on a panel of 30 tumors and primary cells, further showing its high specificity and indicating that SAR131675 is not a cytotoxic or cytostatic agent. Clarification of the content of PVC in consumer products is urged.

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The results contradict the idea that vegetative desiccation tolerance in the resurrection angiosperms Craterostigma and Xerophyta arose through the co-option of genes exclusively related to stress tolerance, and support the propagule-derived origin of vegetative desiccation tolerance in the resurrection plants. Macrophage triggering with cecropin A and melittin-derived peptides induces type II nitric oxide synthase expression.

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Effects of exposure to static magnetic field on motor skills and iron levels in plasma and brain of rats. Infiltrating cells in mouse cardiac allografts after anti-CD4 monoclonal antibody treatment. Cancer cell characteristics may play a pivotal role in the response to therapy by activating or deactivating different molecular pathways.

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Here, we provide a review of all of the important types of myoclonus encountered in pediatric and adult neurology, with an emphasis on the recent developments that have led to a deeper understanding of this intriguing phenomenon. This review contains a panel of tools to explore mitochondria and to help researchers design experiments, determine the approach to be employed, and interpret their results. Misoprostol seems to be a drug with many potential uses apart from the treatment of gastric and duodenal ulcers.

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Hemifacial microsomia (HFM) is a variable, complex malformation involving asymmetric hypoplasia of the face and ear. In view of the increasing use of CAM by the general public, it is imperative to promote credible research by the established biomedical community. Color Doppler ultrasound analysis of ocular circulation after topical calcium channel blocker.

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The diverse nature of viral populations allows rapid adaptation to dynamic environments, and evolution of resistances to vaccines as well as antiviral substances. GABA maintains the proliferation of progenitors in the developing chick ciliary marginal zone and non-pigmented ciliary epithelium.

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Tears may extend after radial-relieving incisions have been used to enlarge a contracted anterior capsulotomy, possibly because of continued capsular fibrosis. A promising method of hygienic evaluation of air pollution inside the modules of the international space station by hydrazine derivatives Community programmes to ensure adequate child supervision and general child wellbeing, particularly for those with impairments, as well as parental education about burns are recommended, to reduce childhood burns in this region of Ghana.

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Discussions have been going on since the publications of Bertolotti (1917) and Blumensaat and Clasing (1932) as to whether variations in the lumbosacral region and vertebral anomalies, which may alter the statics of the vertebral column, result in typical neurological disorders. The interaction between HCCA2 and MAD2L2 was confirmed by in vitro and in vivo binding assays and the interaction domain was mapped to the N-terminus of HCCA2 by sequential deletion. The glycocalyx decorates the luminal surface and affords critical protection of the endothelium. Any individual strand appears to have several choices of path, which accounts for the observed disorder at high resolution.

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A dual immunofluorescence staining method was developed using primary antibodies of differing isotypes and secondary antibodies labeled with fluorophores having nonoverlapping emission characteristics. Initial hemodynamic evaluation revealed mitral valve prolapse and evidence for isolated right to left shunting, presumed to be extracardiac.

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Treatment of fungal spondylitis is often delayed because of difficulty with the diagnosis. German civil law differentiates between continuous and temporary mental disorder. A numerical method to determine the steady state distribution of passive contaminant in generic ventilation systems.

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Estrogen stimulation increases expression of BRCA1 at the mRNA and protein level and conversely BRCA1 functions to both induce ERalpha mRNA expression and act as a negative regulator of ERalpha signaling. Shiftwork and impaired glucose metabolism: a 14-year cohort study on 7104 male workers. Using non-stationary fluctuation analysis, we obtained an estimate of the single-channel conductance of 4 pS, which is well below that expected for channels containing both the 5-HT(3A) and 5-HT(3B) subunits. The interaction of urokinase-type plasminogen activator (u-PA) or of u-PA amino-terminal fragment (u-PA-ATF) with the cell surface receptor (u-PAR) was found to stimulate an increase of glucose uptake in many cell lines, ranging from normal and transformed human fibroblasts, mouse fibroblasts transfected with human u-PAR, and cells of epidermal origin.

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Diagnosis by measurement of specific adrenocortical precursors and initiation of therapy with dexamethasone. A detailed patient history is the most reliable predictor of latex sensitivity.

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Heparan sulfate displays a range of biological functions, and heparin is a widely used anticoagulant drug in hospitals. Haemoproteus infections can cause fatal disease in parrots (Psittaciformes), one of the most endangered groups of birds.

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There was no significant change in cardiac index and arterial oxygen delivery after the injection of bupivacaine. In contrast, increased protein degradation leads to skeletal muscle atrophy. The specific activity of CLEAs prepared from wild type LS (44.9 U/mg of CLEA), R360K (56.5 U/mg of CLEA) and Y429N (1.2 U/mg of CLEA) mutants were approximately 70, 40 and 200-fold higher, respectively, than equivalent Eupergit C immobilized enzyme preparations (U/mg of Eupergit), where units refer to global LS activity. TRPV6 mRNA levels in the endometrium were increased by estrogen treatment.

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People with better health resources were more likely to report goals related to leisure-time, social and physical activities and less likely to report goals related to recovery of health. Prognostic significance of programmed cell death-1-positive cells in follicular lymphoma patients may alter in the rituximab era. The teeth were irradiated with Er:YAG laser at approximately 75 J/cm(2)/pulse and 20 Hz under water spray for 60 minutes.

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All the above-mentioned evidences suggest that CR induces the apoptosis of human leukemic U937 cells via the changes in cytokine profile and protein expressions in mitochondria pathway and that CR has the potential to be used in the therapy of leukemia due to its strong apoptosis-promoting effect. Ability of garlic-derived diallyl disulfide and diallyl trisulfide supplemented by oral gavage to mitigate effects of an acute postweaning feed and water deprivation event in nursery pigs. The levels of acid phosphatase and alkaline phosphatase in the individual enterocytes are significantly greater in the jejunum, according to quantitative histochemical analysis. In this study a 24-h pH and oesophageal motility recording system was used to study naturally occurring acid reflux episodes in control subjects and in two groups of patients with severe acid reflux disease (erosive oesophagitis and oesophageal stricture). Previous research has suggested that going along with psychotic symptoms (symptomatic coping) is less effective than other coping strategies with psychotic symptoms.

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Autapomorphies in the ground pattern of the monophylum Acanthocephala are the four eggshells, the early development of three syncytia, the condensed nuclei in the central syncytium, and the differentiation of ten longitudinal muscle bands and two muscle retractors and of intraepidermal hooks and spines. The therapeutic efficacy of atropine and salbutamol sprays alone or in association was experimented in patients with atopic bronchial asthma as part of an investigation of the bronchodilatatory drugs and the pathogenesis of bronchospasm. It also describes the processes occurring onto the surface of hemosorbents on their contact with blood. Management of atrial fibrillation alternating between complete heart block and rapid ventricular response.

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Sensitivity to motion features in point light displays of biological motion. Salivary IgA and IgG in oral lichen planus and oral lichenoid reactions diseases. Here we report that treatment with an agonistic monoclonal antibody to CD137 (2A) blocks lymphadenopathy and spontaneous autoimmune diseases in Fas-deficient MRL/lpr mice, ultimately leading to their prolonged survival. The hybridization patterns indicated that corresponding sequences were homologous to several chromosomal regions.

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Biomedical applications of photoacoustics, in particular photoacoustic tomography, require efficient models of photoacoustic propagation that can incorporate realistic properties of soft tissue, such as acoustic inhomogeneities both for purposes of simulation and for use in model-based image reconstruction methods. Systematic review of design and effects of splints and exercise programs in hand osteoarthritis. These results indicate that AH66 cells are a naturally acquired multidrug-resistant cell line overexpressing a P-glycoprotein, and AH cell lines are useful to study multidrug resistance of hepatic carcinomas and development of counteracting drugs.

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The nutrient-load hypothesis: patterns of resource limitation and community structure driven by competition for nutrients and light. The identification of gene differential co-expression patterns between cancer stages is a newly developing method to reveal the underlying molecular mechanisms of carcinogenesis.

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How to diagnose pregnant women with drug abuse problems and which ones need support Two subsequent surveys were mailed to non-respondents at 15 days intervals. Seizures characterized by short duration and low frequency usually may be the first symptom in newborns with cerebral infarction. Primary vasculitis of the central nervous system in patients infected with HIV-1 in the HAART era.

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Receptor or proteases induce conformational changes in case of rhinovirus, poliovirus or adenovirus, and thereby provide direct uncoating cues. Two female pediatric patients with advanced stage malignant Astrocytoma tumors. Characteristics of actin fibers and ultrastructure of the contact regions involved in the separation of blastomeres of two-cell mouse embryos, frozen-thawed without the zona pellucida.

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The source of this was found to be the rubber seals used to seal the glass bottles in which the IOLs were stored. Curricula informed by these three interests are referred to as curriculum as product, curriculum as practice, and curriculum as praxis (Grundy, 1989) respectively. Solid pseudopapillary epithelial neoplasms (SPENs) of the pancreas are rare but curable tumours that have a low-grade malignant potential and occur almost exclusively in young women, with an excellent prognosis after complete resection. Interfering with disease: a progress report on siRNA-based therapeutics. The diagnostic accuracy of the immunocytochemical markers in the pre-operative evaluation of follicular thyroid lesions.

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The vascular leakage was evaluated in vitro on endothelial cells by a transwell model system and in vivo on rat mesentery microvessels by intravital microscopy. Thus, TGF-beta1 and MMP2 may be useful molecular markers for evaluating prognosis in RCCC patients. Earlier work has suggested that familial Mediterranean fever, an inherited disorder characterized by sporadic episodes of inflammation involving the pleural and peritoneal cavities and the joints, is caused by the lack of a C5a inactivator normally found in serosal fluid.

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No role for N-acetylcysteine in the treatment of thallium poisoning was demonstrated by this study. Also BAEPSs show significant alterations in the uraemic group (latencies of the III, V components). We report a case of acquired protein energy malnutrition with associated zinc deficiency in an 18-month-old boy with type 1 glutaric acidemia. None of the strains named for inclusion in the challenge test outlined in the European Pharmacopoeia are associated with the contamination of high-quality water used in pharmaceutical production.

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No studies have evaluated the consultation process or attempted to define a standardized approach that could improve communication and patient outcomes. In this paper, an original finite element (FE) model was developed to inspect the key mechanisms governing the induced damage formation when cutting this multi-phase material. Our data showed that strict quality criteria for RNA integrity assessment and well calibrated and standardized RT-qPCR allows multicentre analysis of genes transcripts with high accuracy in the clinical context. Postoperative analgesia in ambulatory surgery is one of the best reasons to select these techniques.

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Inadequate evidence to guide the management of children with esophageal varices may lead to variation in care and the provision of poor-quality care to some children. However, current knowledge in carboxylic acid crosslinking of proteins and cellulose requires the use of carboxylic acids with at least three carboxylic groups, toxic phosphorous-containing catalysts and curing at high temperatures (150-185 degrees C). A short history of vaccination and troubles connected with preparation of vaccine effective in preventing serogroup B meningococcal diseases was described. Segregating expression domains of two goosecoid genes during the transition from gastrulation to neurulation in chick embryos. Treatment time in dystopia of the cuspid with and without extraction

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Connecticut horror draws much-needed focus to mental health services. The results of sequence analysis of ITS amplification products revealed genes for Ile-tRNA and Ala-tRNA in all strains tested. Clinical follow-up was scheduled at 1, 6, 12, 24, and 36 months. Incoherently combining logarithmic aspheric lenses for extended depth of field.

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Serum esterase inhibition in birds: a nondestructive biomarker to assess organophosphorus and carbamate contamination. This study has demonstrated the usage and theoretical basis of reflectance spectroscopy, which is a rapid and inexpensive analytical method, for evaluating contamination by heavy metals and their binding forms in sediments. Noonan syndrome is a genetic multisystem disorder characterised by distinctive facial features, developmental delay, learning difficulties, short stature, congenital heart disease, renal anomalies, lymphatic malformations, and bleeding difficulties. Pain control in recovering alcoholics: effects of local anesthesia. Analysis of ommatidia mosaic for wild-type and groBFP2 mutant cells suggests that the focus of action of the groBFP2 mutation is outside of the photoreceptor cells.