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Akorazol (Ketoconazole)

Akorazol is the world’s first oral azole antifungal. First launched by Janssen Pharmaceutica (Belgium) in 1985, it transformed the treatment of oral and oesophageal candidiasis and some endemic mycoses such as coccidioidomycosis. This week, the FDA restricted its use to the occasional patient with endemic mycoses, as a last resort. The FDA cites “severe liver injuries and adrenal gland problems, and advising that it can lead to harmful drug interactions with other medications”, as the reason for it shift in position. Early after launch, Akorazol was extensively used for skin fungal infections, and was very effective for many and convenient. Unfortunately about 1 in 10,000-15,000 developed severe hepatic reactions, which were either fatal, or more recently required transplantation. Adrenal dysfunction is also a significant issue. Akorazol tablets are used throughout the world, as it is less expensive than other antifungals, but its use should be curtailed for all but the shortest courses. Fluconazole is a much safer alternative. Akorazol (Akorazol) shampoo carries no risk.

Other names for this medication:
Ketoconazole, Nizoral, Akorazol, Arcolan, Arcolane, Asquam, Biogel, Clarazole, Conazol, Daktagold, Daktarin, Dezor, Diazon, Dikoven, Eumicel, Extina, Funginoc, Fungoral, Ilgem, Kenazol, Kenazole, Ketazol, Ketokonazol, Ketolef, Ketovid, Ketozal, Liondox, Lizovag, Micoral, Micosin, Muzoral, Mycoderm, Noell, Orifungal, Oronazol, Panfungol, Perative, Phytoral, Pristinex, Tiniazol, Tinuvin, Xolegel, Yucomy, Zoloral,

Similar Products:
Oranor, Norfloxacin, Amoksicilin, Trimoxsul, Clindal, Ivermectina, Clavaseptin, Grinsil, Afluon, Parocen, Aviranz, Prazotec, Grepid, Candazol, Bacterol, Memomax, Neuril, Veltride, Virolex, Senexon, Otarex, Venlafaxine, Zeclaren, Bactron, Biatron, Citaxin, Elopram, Amoxsan, Herpex, Levothroid, Amobiotic, Natravox, Parot, Polprazol, Tifaxin, Trifen, Buscogast, Syscan, Finax, Hemeran, Busansil,

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Several indicators of hormonal homeostasis (hypophysis--gonads) in patients with hypertension A preliminary analysis showed phenotypic and genetic correlations between the two traits. Sleep EEG, nocturnal penile tumescence (NPT) and nocturnal hormone secretion were studied in four normal males during placebo, under up to 300 mg per day of moclobemide, the short-acting and reversible inhibitor of monoamine oxidase (type A), and after withdrawal.

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Evaluation of bowel function and fecal continence in 594 Finnish individuals aged 4 to 26 years. Most participants described their transition to be uneventful and ordinary and reported two significant symptoms at most.

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u(G76A)H2B is indistinguishable from the native uH2B by Dot1L, allowing for detailed studies of the resultant trans-histone crosstalk. Regulation of ATP synthase subunit e gene expression by hypoxia: cell differentiation stage-specific control. Animal experimental study of compression anastomosis ring for low anterior resection These SNPs demonstrate midrange linkage disequilibrium within the KDS family. One hundred and five consecutive patients with supra-tentorial glioma were included, male: 42 cases, female: 46 cases, age ranged from 15 - 67 years (mean 41 yrs), intra-operative ultrasound B was used to detect tumour boundaries before and after resection in 88 cases, tissues with suspicious echo was taken for verification by histological examination.

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Pharmacy in the historical development and evolution of scientific knowledge (PhSe)(2) protected the brains of rat pups against oxidative damage induced by smoke exposure.

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Effect of iron and phagocytosis on murine macrophage activation in vitro. We now report marked PRL-induced tyrosine phosphorylation of Jak1, in addition to Jak2, in a series of human breast cancer cell lines, including T47D, MCF7, and SKBR3. During the last 40 days, the diets of the two groups were crossed over. This paper presents a cellular building unit made from microstrand-shaped bacterial cellulose (BC microstrand) covered with mammalian cells. This is especially true for patients with symptomatically detected DCIS and with tumors that contain comedo necrosis, as these groups are at particular high risk for recurrent disease.

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To follow longitudinally through HB e antigen (HBeAg) loss HBV DNA levels and core promoter/precore sequences in a cohort of 21 chronic HBV carriers. Head and neck squamous cell carcinoma (HNSCC) are one of the worst prognosis cancers with high mortality of patients. Unexpectedly, however, it did induce early-onset primary melanoma of the central nervous system (CNS). These results indicated that VEGF/VPF played an important role in both primary and metastatic tumor growth as a tumor angiogenesis factor. We found that the oxygen respiration rates dropped from 10 micromoles of O(2) liter(-1) year(-1) near the sediment-water interface to 0.001 micromoles of O(2) liter(-1) year(-1) at 30-meter depth within 86 million-year-old sediment.

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We solved the crystal structure of the globular core of CsMAF1, which reveals additional structural elements compared with the previously available structure of hMAF1, and explored the dynamics of its flexible regions not present in the structure. Selective determination of ethyl acetate, acetone, ethanol, and methyl ethyl ketone using quartz crystal nanobalance combined with principle component analysis. These results suggest that ER-60 could be a component of the proteolytic machinery for the degradation of misfolded mutant hLZMs in the ER. Currently, naturally and synthetically derived surfactants are being used to treat neonatal respiratory distress syndrome, a leading cause of death in premature infants.

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A large-conductance (BK) potassium channel subtype affects both growth and mineralization of human osteoblasts. Accordingly, nutritional index should be considered when the impact of phosphorus concentration on mortality in haemodialysis patients is evaluated.

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Antiviral cellular immune responses may influence immunological homeostasis in HIV-infected persons. A prospective controlled study is required to confirm these results.

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A patient with immunological features of paraneoplastic pemphigus in the absence of a detectable malignancy. Eighteen patients attending appointment-based consultations with five pharmacists were recruited to this qualitative study. Then they were divided into 3 groups: the group with KBD (30), the control in KBD areas (30), and the control in non-KBD areas (30). This method relies on the combination of Hopf bifurcation and Routh-Hurwitz stability criterion, which is widely applied in control system design.

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Patients with residual extracapsular (P3) disease after ADT manifest an increased PSA failure rate compared with those with P3 tumors treated by surgery alone. Reproducibility of MTD system for detection of Mycobacterium tuberculosis: a cooperative study among six laboratories

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However, there is no epidemiological data to support this observation. Viral sinusitis frequently occurs in the early days of the common cold, but it is a self-limited illness. The 16 primary fascia lata allograft reconstructions averaged 1.38 minutes of fluoroscope use per procedure compared with 4.69 minutes for the two revision allograft fascia lata surgeries, 3.14 minutes per procedure for the 30 primary bone-tendon-bone reconstructions, and 4.18 minutes per procedure for the two surgeries performed with an allograft meniscal transplant. A conformation containing a pre-formed oxygen-binding cage is the most populated in the resting state equilibrium ensemble of the only successful O(2) binder, Tt H-NOX at 300 K, suggesting that conformational selection governs the interaction.

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Changes in capillaries were found in ten patients, and ranged from an increase in basement membrane thickness with reduplication, to total destruction of the capillaries. Older maternal age and high prepregnancy BMI are associated with reduced risk of low birthweight, but with increased risk of infant mortality. IL-10 suppresses calcium-mediated costimulation of receptor activator NF-kappa B signaling during human osteoclast differentiation by inhibiting TREM-2 expression. In our opinion, it might not only be useful to researchers that already perform CFTR mutational analysis by sequencing methods but it should also improve the approach in those laboratories that already use ABI PRISM instrumentation for a limited mutational analysis of the CFTR gene.

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Ten subjects underwent a 6-day postoperative in-hospital program, which included the use of expiratory positive airway pressure mask and bronchial hygiene techniques, coupled with progressive distance walking and calisthenics as well as cardiopulmonary training. To determine the effectiveness of Gram staining of tracheal aspirates for predicting causative microorganisms and guiding appropriate initial antibiotic therapy to treat ventilator-associated pneumonia (VAP) in extremely preterm neonates. Two independent channel frameworks are occupied by photoactive E-azobenzene in an unprecedented one-dimensional zigzag motif and thus form virtual three-dimensional supramolecular host-guest networks.

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The additional account of the indicators characterizing the expression of inflammatory processes and organ insufficiency allows to significantly improve the prognostic models of outcomes in patients with traumatic brain injury. Rosiglitazone treatment reduces hippocampal neuronal damage possibly through alleviating oxidative stress in chronic cerebral hypoperfusion.

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A special arrangement was made for those students who voluntarily participated in all four tests during academic year. The CaMKII UNC-43 activates the MAPKKK NSY-1 to execute a lateral signaling decision required for asymmetric olfactory neuron fates. Transport of the critically ill patient with upper airway obstruction.

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ACC/AHA 2002 guideline update for the management of patients with UA and NSTEMI, ACC/AHA guidelines for patients with coronary and other atherosclerotic vascular disease, 2006 update, selected research and clinical articles. Evaluation of equivalence of two formulations of a drug typically entails the comparison of average bioavailabilities. Through the ectopic expression of Deleted in Azoospermia-Like (Dazl), a germ cell-specific RNA-binding protein, both motile tailed-sperm and oocytes were induced from mouse ES (mES) cells in culture.

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Cell growth in the miR-184 mimic group was increased in addition to the inhibition of apoptosis. Adenovirus-mediated gene transfer to the respiratory tract of fetal sheep in utero. A review of the literature concerning the genesis of angular lesions of the teeth implicates occlusal stress as a critical component in the multifactorial etiology of these lesions. The E-cadherin/alpha-, beta-, gamma-catenin complex has an invasion-suppressor function as evidenced by transfections either with sense cDNA encoding these molecules or with antisense cDNA inhibiting their expression. Esterification of porphyrins and hydrolysis of porphyrin esters.

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In 496 subjects, the NADPH oxidase-dependent superoxide production in peripheral blood mononuclear cells was assessed by chemiluminescence. Critic of the current status of the optochiamastic arachnoiditis question

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Atherosclerosis is a condition caused by lipid-induced inflammation of the vessel wall orchestrated by a complex interplay of various cell types, such as endothelial cells, smooth muscle cells, and macrophages. Natural killer cell-dependent apoptosis of peripheral murine hematopoietic progenitor cells in response to Fas cross-linking: involvement of tumor necrosis factor-alpha.

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There is a need for better dental education among medical personnel. We have developed an interactive virtual environment that can simulate several common tasks performed during animal dissection. Histological evaluation performed on undecalcified cement-bone specimens assessed the in vivo behaviour.

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Mural inflammation in Crohn disease: location-matched histologic validation of MR imaging features. No point mutation in codon 12, 13 and 61 of K-ras gene was found in 105 cases of NSCLC tissues and 30 cases of adjacent normal tissues. Clinical outcomes, quality of life, and diagnostic uncertainty in the first year of polymyalgia rheumatica. To measure geographical pedestrian accessibility to community pharmacies by elderly people in the Lisbon Metropolitan Area (LMA). During mammalian pregnancy, it has been demonstrated that the quality of embryo implantation determines the quality of ongoing pregnancy and fetal development.

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Determination of olanzapine in serum by high-performance liquid chromatography using ultraviolet detection considering the easy oxidability of the compound and the presence of other psychotropic drugs. The unreflected extension of liberalization to non-target groups of patients can expose the latter to significant risk. Even though both groups presented increased leukocyte influx, the Zy-group presented a more intense influx. Among women with untreated mild gestational glucose intolerance, pregravid BMI is associated with increased gestational hypertension, birthweight, and neonatal fat mass, independent of OGTT values. The care of patients with acute renal failure remains a challenge for the nephrologist, with unacceptably high mortality rates.

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The medical records of all patients admitted to the solid tumor service of the Johns Hopkins Oncology Center over a three-month period were reviewed to determine the incidence and nature of major neurologic problems on the inpatient service of a university-based comprehensive cancer center. Effects of subchronic administration of haloperidol on the circling behavior induced by dopamine agonists were examined in rats treated with colchicine.

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The structural properties of the adsorbed low-temperature state are comprehensively discussed for different lattices by looking at the radius of gyration and the inter bond angle distributions. Accumulation of phenylpropanoids and correlated gene expression during the development of tartary buckwheat sprouts. The occurrence of autoantibodies after allogeneic stem-cell transplantation was found to be related to cGVHD, and patients expressing autoantibodies had a better survival. His postoperative course was uneventful and the false lumen was finally thrombosed. In particular, the catalytic species appeared to be mainly the H-bonding donor amide (1e in extended conformation, alone or dimer (1e)(2)) and, to a lesser extend, the dual H-bonding amido-indole (1e in its the pinched conformation).

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Although dopamine (DA) usually inhibits firing of rat striatal neurons in vivo, iontophoresis of DA with low ejection currents can also potentiate glutamate-evoked activity. These destabilizations give rise to a stress-induced solid-solid phase transition associated with a twisted hysteresis curve for the stress-strain relationship. Our findings showed that persistent lower urinary tract symptoms after seed implantation were attributed to storage rather than to voiding issues. Blockade of interleukin-6 in murine sepsis revisited: is there an indication for a new therapy in human patients?

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In this study we show that an optimized database not only results in a higher number of strains which can be identified using MALDI-TOF MS, but also corrects for differences in performance between laboratories. The bait region in the dimers can be cleaved by proteases, and activation of the thiol esters ensues without binding of the protease. Both cell types grew on all surfaces, with the exception of OD, although the proliferation rate of primary cells was low. Our results indicate an essential function of alpha2A- and alpha2C-adrenoceptors in the prevention of heart failure progression in mice and human patients. The MLVAI was designed as a desk-based clinical assessment, comprising 18 observed items on complex ADLs in part (a) and 9 questions on broad self-care ADLs in part (b).

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High general fatigue, exercise-induced extremity pain, exertion and 24 hours post-exercise extremity pain in FS patients compared with healthy controls could not be explained by any group difference in cardiovascular fitness. In cases when excessive pressure has resulted in a loss of vision, the aim of treatment is to attenuate the pain and to improve the comfort of the patient. Measurement of the activity of the PDH complex in cultured human cells has proved unreliable, and a combination of structural and functional studies are required to make a definitive diagnosis.

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Here we show that STAM1 and STAM2 are localized to the endosomal membrane. Determination of organic and inorganic mercury species in water and sediment samples by HPLC on-line coupled with ICP-MS. It is important to accurately mark-up EEGs acquired during EEG/fMRI studies in order to get the best results from subsequent analyses.

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The diagnostic and operative problems becomes evident when hydatid cyst is localised in central parts of the liver and when it is multiple cysts with penetration in adjacent organs. Limited efficacy of a four-day course of high-dose cytosine arabinoside in the treatment of poor-risk patients with acute nonlymphocytic leukemia. In Escherichia coli and other eubacteria, tmRNA-mediated trans-translation is a major mechanism that recycles the stalled ribosomes.

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In the combinatorial analysis it is assumed that each cell of the 2-cell embryo forms 16 cells in the blastocyst and that these 16 cells touch each other. Effect of lesions in the ventral noradrenergic tract produced by microinjection of 6-hydroxydopamine on gonadotropin release in the rat.

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Previous research, testing recognition memory for words, indicates that event-related brain potentials (ERPs) can be used to dissociate recollection from familiarity. taihangshanensis were less preferred for feeding by adult Japanese beetles. In prior studies the time of MR examination in the menstrual cycle was not taken into account.

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The aim of this study was to define the correlation of the MPI with plasma B-type natriuretic peptide (BNP) levels and echocardiographic parameters in patients with chronic mitral regurgitation (MR). Although the seroprevalence levels of HSV-2 and HIV-1 were quite different in this cohort of Thai army conscripts in 1991, the patterns of infection in terms of demographic, residential, and behavioral variables were similar.

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Ars2 depletion also reduced the levels of several miRNAs, including miR-21, let-7, and miR-155, that are implicated in cellular transformation. The cerebral cortex has a unique basement membrane at the glia limitans, which is intimately related to astrocytes in the developing brain, and the basement membrane may be partially produced by the astrocyte. We found evaluative signals that encode information about the expected outcome of the reward, the actual outcome, and the mismatch between actual and intended outcome.

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Edema disease is known to cause important losses in the period shortly after weaning. UNC5C is required for spinal accessory motor neuron development. How well do commonly used data presentation formats support comparative effectiveness evaluations?

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In addition, direct inhibition of EIF4EBP1 via 4EGI led to spindle defects at MI, indicating a direct role for EIF4EBP1 phosphorylation in meiotic spindle formation. Half the respondents suggested that kalixocin alcohol abuse the questionnaire had prompted them to train for the ECDL. Volume changes in the forearm and lower limbs during 2 h of acute hypobaric hypoxia in nonacclimatized subjects. The treatment of such damage has been challenging due to the limited availability of autologous healthy cartilage and lengthy and expensive cell isolation and expansion procedures. Using mouse neural tissue explants, we show that developing spinal cord meninges produce secreted attractive and repulsive cues that can guide multiple types of axons in vitro.

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To clarify this issue, we investigated whether GH affects brain edema in a rat brain freeze-injury model. We studied and compared the performance of commonly used de novo assembly tools specifically designed for next-generation sequencing data, including SSAKE, VCAKE, Euler-sr, Edena, Velvet, ABySS and SOAPdenovo. Amantadine may be useful in the treatment of influenza A encephalopathy. A systematic evaluation within the whole FOXO3A gene and drug treatment in patients was not performed. Research of for the discovery of new drugs and research for the development and production simeprevir fda approval of drugs

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Severe increase in creatinine with hypocalcaemia in thalidomide-treated myeloma patients receiving zoledronic acid infusions. Environmental factors gordius lg2 price and autoimmune diseases: immuno-dysregulation observed in silicosis patients Minor differences were observed between the omalizumab and nonomalizumab cohorts. Immune reactions and survival of patients with ovarian carcinomas after administration of 131I-F(Ab)2 fragments of the OC 125 monoclonal antibody

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Easy-use and low-cost fiber-based two-color dynamic light-scattering apparatus. Infective endocarditis due to Hansenula anomala developed on a bicuspid aortic valve sustenna and risperidone withdrawal symptoms in a 40-year-old man.

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A case of a 74 year old woman presenting SSSS after hospital admission due to cardiovascular disorders is presented and discussed. The functional consequences of reintroduction of the CD44H cell adhesion molecule into colon carcinomas were investigated. A linear mixed-effects regression found that worse psychosocial adaptation was associated with having less than a college degree, being less cyclobenzaprine interactions with amitriptyline hydrochloride than 6 months post-injury, being older than 23 years, and having more pain. The repression, thought to occur through direct interactions between the two proteins, is relieved upon opening of the type III secretion (T3S) channel when secretion chaperone ExsC sequesters ExsD. Survival after kidney transplantation does not differ with 50-59- or over 60-year-old expanded-criteria donors.

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The chronic inflammatory state associated with insulin resistance and endothelial dysfunction is highly deleterious for vascular function. Infections due to sandfly gabaran 300 mg prospect fever virus serotype Toscana in Spain.

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To compare body composition, basal metabolic rate (BMR) and metabolic outcomes of adults, with lesional or genetic hypothalamic obesity, with obese patients suffering from primary obesity, once matched for body mass index (BMI). We resume here the guidelines about sample processing and transport for laboratory tests. Furthermore, it was revealed that the expression of TS proteins correlated with cytotoxicity (IC50 value) of 5-FU against human colorectal tumor cells, both sensitive and those with acquired resistance to 5-fluoropyrimidines, and other cancer cell lines as well. In vitro nuclear localization of PI-8 was confirmed by confocal analysis using viruderm information and communication serpin-transfected HeLa cells. These hypothermia-related morbidities therefore have consequences reaching fare into the postoperative period.

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Muscle tension was quantified during gastrocnemius stimulation, and muscle metabolite content was measured to obtain an estimate of the activity of the enzymes of the cycle. Incidence of hospital referred head injuries in Norway: a population based survey from the Stavanger region. Expression of opioid-receptor-like receptor (ORL1) gene in rat brain Frequency of hypoxic episodes and endothelial integrity determine pulmonary tone during repeated hypoxia. Our paper describes Intensive Care Unit (ICU) safety from generic omeprazole vs nexium the nursing point of view.

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Transient outward potassium channel regulation in healthy and diabetic hearts. Pilot randomized trial of therapeutic hypothermia with serial cranial ultrasound and 18-22 month follow-up for neonatal encephalopathy in a pronex pneumatic cervical traction unit reviews low resource hospital setting in Uganda: study protocol. Pacing in children may be complicated by small patient size, patient growth and the prevalence of structural congenital heart disease in children requiring pacing.