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TORC1 regulates activity-dependent CREB-target gene transcription and dendritic growth of developing cortical neurons. Influence of temperature and humidity on laser in situ keratomileusis outcomes.

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Using high-resolution methylation profiles of erythroblasts and other tissue types, 3 genomic loci were found to be hypomethylated in erythroblasts but hypermethylated in other cell types. Synaptic differentiation of a single motor neuron: conjoint definition of transmitter release, presynaptic calcium signals, and ultrastructure. Production of the phytohormone indole-3-acetic acid by estuarine species of the genus Vibrio. When the technique has been mastered transfemoral cannulation of the renal vessels can be used in routinely in the clinic Critical consideration of the indications, however, is necessary. For example, the catalytic subunit of phosphoinositide 3-kinase (P13-K) was recently identified as an oncogenic protein.

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Muscle activation and deactivation dynamics: the governing properties in fast cyclical human movement performance? The data analysed were the evolution of the articles throughout the analysed period, languages of publication, index of authorship, countries according to author affiliation, subject matter, the ten most cited articles, Top Ten journals in which Psicothema is most cited, and the evolution of the Impact Factor, amongst others. Social isolation has profound effects on animal behavior and dopamine systems. Ischemia and subsequent reperfusion (IR) may induce local and remote organ reperfusion injury.

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For the first time, the cytotoxic activity of RTS11 against xenogeneic targets has been demonstrated, although this was modest relative to HKLs. In this review we discuss the role of different diagnostic methods with respect to patient selection and surgical outcome. The indications for the procedure were infertility (21), swelling (3), pain and discomfort (9) and asymptomatic varicoceles (5). In human CRC tissues, SNAIL regulates expression of IL-8 and other genes to induce cancer stem cell activities. Trace metal ratios in human bones were examined to determine if there were ratios that were sufficiently consistent within an individual yet varying sufficiently from the bones of another individual so that bones in a mixed grave could be reassembled.

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Oral vitamin A as an adjunct treatment for canine sebaceous adenitis. In conclusion, peripheral injection of CCK-8 and ceruletide may affect directly or indirectly dopamine function producing behavioral changes that resemble those of neuroleptics in some respects. Utility of the pp65 direct antigenemia test in the diagnosis of cytomegalovirus (CMV) in renal transplant recipients.

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Plasma samples for determination of HMGB1 and sRAGE levels were collected on admission and on days 1 and 2, days 3 and 4, and days 7 and 12 after admission. We examined the effects of ibotenic acid induced unilateral lesion of the nucleus basalis magnocellularis (nBM) on carbachol- and serotonin-stimulated phosphoinositide (PI) breakdown in miniprisms obtained from rat fronto-parietal cortex 1 week following the lesion.

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Care plans are perceived to be a useful tool to both health care providers and parents of CMC. Throughout the urethra the distribution of AChE-positive nerve fibres was uniform, but the number was clearly less than in the urinary bladder. An increase in the level of lipid peroxidation products in liposomal suspension as the consequence of the earlier oxidation of liposomal lipid leads to a considerable increase in the antibacterial activity of liposomes. This study was to seek evidence for splicing factors that might direct formation of the exon 4 minus ENOX2 splice variant. Research was carried out to determine whether the likelihood of obtaining a positive Acid Phosphatase (AP) test result is affected by the make and type of paper used.

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After adjustment for age and gender, subjects in the PTSD-positive group had significantly higher scores for inter-group conflict, role ambiguity, and CES-D, as well as significantly lower scores for social support from their supervisors compared to those in the PTSD-negative group. Even therapeutic administration of flurbiprofen axetil after the onset of MTS has also effects on MTS by suppressing prostacyclin production.

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Conceptuses were collected on Days 11, 13, 15, 16, 17, 21, and 30 after mating. Ligand-induced phosphorylation of a subset of proteins was reduced in beta-PKC-depleted dHL60 cells. Having long been considered inert debris reflecting cellular activation or damage, MPs are now considered as cellular effectors involved in cell-cell crosstalk. In this study, we showed that the Arg-Gly-Asp-containing peptides (including naturally occurring polypeptides, triflavin, trigramin and rhodostomin, synthetic peptides GRGDS, GRGDSPK, GRGDF, and GRGD and monoclonal antibodies, 7E3, 10E5 and AP2, raised against glycoprotein IIb/IIIa complex, inhibited the adhesion of activated-platelets to fibronectin and vitronectin-coated plates in a dose-dependent manner.

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Although guidelines for the diagnosis and clinical staging of diabetic neuropathy have been proposed, only nerve conduction studies can provide a reliable diagnosis of the condition. Different processes used to fractionate the sediment sample were compared using solvents with different polarities. Behavior of the glucose-6-phosphate dehydrogenases and reduced glutathione of the erythrocytes of the newborn at term and of prematures

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Prevalence of sexual activity and associated factors in hypertensive males and females in China: a cross-sectional study. Biomechanical investigations were performed on human menisci using 6 commonly used biodegradable implants for meniscal repair to compare them with horizontal mattress suture using 2/0 Ethibond (Ethicon, Norderstedt, Germany). Diarrhea-predominant irritable bowel syndrome: creation of an electronic version of a patient-reported outcome instrument by conversion from a pen-and-paper version and evaluation of their equivalence. We review here the fundamentals of Fourier analysis with emphasis on the analysis of transient signals. Conserved sequence motifs were observed which may mediate the effect of high light intensity and/or low oxygen tension on bop gene expression.

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Drug resistance mutations were examined in the integrase gene by sequence analysis. Magnification ratios of the dimensions at standard and alternative head positions were calculated. Adoption was facilitated with national partners and designing branded materials. To evaluate three different strategies (without or with mydriasis) for community based screening for sight threatening diabetic retinopathy (STDR). In the range of 50 to 100 micro g/d, effects may be dose-related.

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This article presents our experience on teaching biochemical sciences through an innovative approach that integrates concepts of molecular cell biology and protein chemistry. Specific adsorptive capacity of the emulsion enhanced gradually after emulsion injection and reached its maximum (3.5-5 mg of proteins per 1 ml of the emulsion) after 24 hours. It is unknown how cost-effectiveness of this intervention is affected by suboptimal S.

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The acellular dermal matrix (ADM) loaded with KGF-ADM was constructed by means of phacoemulsification solvent evaporation and low temperature drying. At the departments of gynaecology, Herning Central Hospital and Holstebro Central Hospital, approximately one third of all hysterectomies are performed vaginally.

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Peak incidence was recorded in the early 1980s and the incidence is seasonal with most cases occurring in winter. The ability to find image similarities between two distinct endoscopic views is known as feature matching, and is essential in many robotic-assisted minimally-invasive surgery (MIS) applications.

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Three-day old poults were inoculated orally with approximately 10(6) cfu/bird (one group with PT8 and the other with PT4). Add-on therapy with nimodipine in intractable epilepsy of childhood. Loss, humiliation and entrapment among women developing depression: a patient and non-patient comparison.

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We investigated the localization of IAPP mRNA by means of in situ hybridization in tissue sections of rat pancreas. In contrast, mRNAs for other IGFBP superfamily members, IGFBP-rP1 (mac 25) and IGFBP-3, were not up-regulated by AGE. Here, we show that hippocampal apoptosis, synaptotagmin-1, and PSD-95 are involved in the synaptic impairment following developmental ID. Here we develop a method for partially-automated particle image selection when an initial 3D map of the protein under investigation is already available.

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Hospital-acquired malnutrition in children with mild clinical conditions. Failure to diagnose phaeochromocytoma preoperatively: a case report and review of diagnostic criteria. To understand the mechanisms of integration of TN-X in the extracellular matrix, overlay blot assays were performed on skin extracts.

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Mongrel dogs had preconditioning of the latissimus dorsi by a vascular delay procedure followed by CMP 14-18 days later (group I VD). As the aging segment of society grows, the number of seniors diagnosed with macular degeneration will increase. In this paper, we examine how it might affect the cost-effectiveness of sustained vector control. Anatomic type and angiographic measurements of patent ductus arteriosus (PDA) are used to determine the suitability of transcatheter closure (TCC). Our results support a model of drug-induced autoimmunity in which abacavir alters the quantity and quality of self-peptide loading into HLA-B57:01.

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The correlation of the intracranial and arterial pressure signals, arteriolar diameter, and estimates of venous flow exhibit a dose-dependent characteristic by increasing monotonically with increasing progressive states of increasing hypercapnia. Regeneration myocardium by stem cell transplantartion has become a focus in research areas of cardial vascular disease. Outcome of Macular Hole Surgery in Bietti Crystalline Dystrophy. We provided a genetic database of the fungal ITS-D1(fLSU)s in the differently managed soils of upland rice fields. The cause of impaired nutrient absorption is not yet fully understood but may be related to small intestinal blood flow and/or mucosal factors.

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Glutathione reductase has a central role in glutathione metabolism and as such is a potential target for chemotherapy. a liberal transfusion strategy on new or progressive multiple organ dysfunction syndrome in children post cardiac surgery. As data from deep mutational scanning experiments become increasingly widespread, phydms will facilitate quantitative comparison of the experimental results to the actual selection pressures shaping evolution in nature. We have treated 42 consecutive complex ununited fractures of the femoral shaft by wave-plate osteosynthesis at five different medical centres.

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Fluphenazine, and particularly olanzapine are associated with an increased incidence ofdiabetes. Sixteen patients with biopsy-proven inactive IBD (8 with Crohn disease and 8 with ulcerative colitis), 9 patients with IBS, and 7 healthy controls completed the Pittsburgh Sleep Quality Index, Epworth Sleepiness Scale, Inflammatory Bowel Disease Questionnaire, SF-12, and a single overnight polysomnogram. The parasite was compared on the one hand with Encephalitozoon, which exhibits asynchronous intravacuolar development of merogonic and sporogonic stages and has spores with isofilar polar tubes and on the other hand with species reported from mammals, of which the sporogonic stages develop synchronously within sporophorous vesicles and the spores have anisofilar polar tubes.

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Clinical and morphological characteristics of gastrointestinal stromal tumors Conversely, mitochondrial transmembrane potential is impaired only when plasma membrane permeability starts to be altered, that is, in relatively later apoptotic cells, thereby reflecting the complexity of mitochondria demise during apoptosis.

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The recombinant scTCR will be used to identify ligands for the CDR3s from random peptide libraries to interfere with TCR binding to the MHC/peptide complex. These results suggest an association between the use of VPA and PCO, hyperandrogenism, obesity and menstrual abnormalities. Decreased degradation and increased biosynthesis play a role in its pathogenesis. Only sVCAM-1 and sE-selectin levels were significantly higher in women with IUGR compared to healthy pregnant women. Comparisons of craniofacial features in monozygous and dizygous triplets.

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The urine output, urinary excretion of sodium, potassium and chloride based on grams of kidney weight, and the diuretic, natriuretic and chloruretic efficiencies decreased significantly in water-deprived rats after both intravenous and oral administration of furosemide, suggesting that the dose of furosemide for water-deprived patients may require modification. Ureteric obstruction by retroperitoneal lymphoplasmacytic lymphoma. We observed abnormally short dynein arms and defective radial spokes.

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Development of an extended simulated annealing method: application to the modeling of complementary determining regions of immunoglobulins. Avoidance behavior and prolactin reactivity to novel environment remained associated in segregating crosses despite gene rearrangement. In vivo transformation of rat plasma very low density lipoprotein into higher density lipoproteins. Inhibition of mitK(ATP)-channels by pretreatment with 5-hydroxydecanoate (5 mg/kg) or MCC-134 (3 mg/kg) completely abolishes cardioprotection and antiarrhythmic effect of adaptation in the 7000 m regimen.

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BRONCHIAL SUPERINFECTIONS: Macrolides are first-line antibiotics for acute bronchitis and infectious complications of chronic bronchitis. Regional sciatic nerve and muscle blood flow in conscious and anesthetized rats. Thioguanine-resistant mutants were induced at similar frequencies in V79A-2 and V79/79 but more ouabain-resistant mutants were induced in V79A-2 than in V79/79.

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An instrument was developed to explore the educational environment that every professor creates for students with indirect technique, with double statements in accordance to the passive and participative focus of the education they approached of the type and frequency of activities carried on regularly in the educational process, validated by rounds of experts, with a final version of 60 statements and six indicators. Both hip and spine-fracture patients have vitamin D insufficiency, with similar results found in elderly patients in four areas of Japan. The chemical quality of this soil C pool reflected ecosystem-specific changes in microbial community composition. The only cells that seem to be directly infected by HIV are the microglia/monocyte and the giant cells derived from fusion of monocytes.

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On the relationship of scores on certain psychological tests with a number of anthropometric characters and birth order in twins. Insurability of the adolescent and young adult with heart disease. The control group consisted of 14 patients receiving donor lungs without surfactant instillation in randomized order. All aneurysms showed a decreased size at 3 months, in spite of 3 small persisting leaks. To determine the expression of the p53 family member p73 in vestibular schwannoma (VS) and to determine the potential role of this tumor suppressor in regulating the proliferation of HEI193, a human papillomavirus E6-E7 immortalized VS cell line.

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The results of this study suggest that airway inflammation and bronchial hyperresponsiveness still persisted during total control of asthma. Drosophila activated Cdc42 kinase has an anti-apoptotic function. Although there is evidence of angina relief and quality of life enhancement, there is little information concerning improvement in myocardial contractility.

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A support group programme for relatives during the late palliative phase. The present review is designed to provide an insight into how SLN are finding a niche as promising nanovectors and forms a sound basis to troubleshoot the existing problems associated with traditional systems. Hierarchical ZSM-5 monoliths with nanotube (90 nm), micropore (0.55 nm), mesopore (2 nm) and macropore (700 nm) exhibit superior catalytic performance in the methanol-to-hydrocarbon (MTH) conversion compared to conventional ZSM-5. We investigate the conversion between two stable configurations (cis and trans) of the CH3S-Au-SCH3 complex on Au(111) by applying density functional theory.

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This, coupled with the observations of greater apparent DNA damage in mammary cells, may be of primary importance in the drug-induced carcinogenicity in the rat mammary tissue. The structure, replication, and expression of the Py viral genome in permissive and nonpermissive infections has been studied extensively in various cell culture systems.

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4) In the presence of SC-26196, controlled refeeding of arachidonic acid, but not oleic acid, reversed the changes resulting from desaturase inhibition. In order to reduce these side effects, especially the immuno-suppressive activity when used to cure cancer, a novel polymeric micelle system containing TP (TP-PM) was constructed. Chromosomal abnormalities in men with pregestational and gestational infertility in northeast China. bicolor MCOs interact with substrates different from those of saprotrophic fungi.

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On logit confidence intervals for the odds ratio with small samples. An interdisciplinary group analyzed the study data using content analysis techniques. Attention process training (APT) reduces attention deficits after traumatic brain injury.

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Furthermore, we show that the Clr3 protein, when mutated, alleviates recombination block at mat region as well as silencing at donor loci and at centromeres and telomeres, also shares strong homology to known histone deacetylases. A potent and novel class of product-like inhibitors of the HCV NS3 protease was discovered by employing a phosphinic acid as a carboxylate isostere. Magnetic resonance imaging (MR imaging) provides a sensitive method for mapping the normal and pathological distribution of iron in the brain. This, in conjunction with previous findings, indicates that ectodermal determinants are localized to the cell cortex in the animal hemisphere of the zygote.